YRC Public Data Repository - Protein Structure Prediction

Protein:	THRC_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	469 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for THRC_PSEAE.

Description	E-value	Query Range	Subject Range
gi\|71736410, gi\|... - gi\|71736410\|ref\|YP_273619.1\| threonine synthase [Pseudomonas syringae pv. phaseolicola 1448A], gi\|71...	0.0	[1..469]	[15..483]
gi\|70728486, gi\|... - gi\|70728486\|ref\|YP_258235.1\| threonine synthase [Pseudomonas fluorescens Pf-5], gi\|68342785\|gb\|AAY90...	0.0	[1..469]	[1..469]
gi\|77381258, gi\|... - gi\|77457255\|ref\|YP_346760.1\| threonine synthase [Pseudomonas fluorescens Pf0-1], gi\|77381258\|gb\|ABA7...	0.0	[1..469]	[1..469]
gi\|28851927, gi\|... - gi\|28868688\|ref\|NP_791307.1\| threonine synthase [Pseudomonas syringae pv. tomato str. DC3000], gi\|28... tr\|Q886U5\|Q886U5... - Threonine synthase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=thrC PE=4 SV=1	0.0	[1..469]	[1..469]
tr\|F3G1T5\|F3G1T5... - Threonine synthase OS=Pseudomonas syringae pv. pisi str. 1704B GN=PSYPI_00795 PE=4 SV=1 gi\|66044539, gi\|... - gi\|66044539\|ref\|YP_234380.1\| threonine synthase [Pseudomonas syringae pv. syringae B728a], gi\|632552...	0.0	[1..469]	[1..469]
gi\|107103250 - gi\|107103250\|ref\|ZP_01367168.1\| hypothetical protein PaerPA_01004319 [Pseudomonas aeruginosa PACS2] gi\|84319534, gi\|... - gi\|84319534\|ref\|ZP_00967929.1\| COG0498: Threonine synthase [Pseudomonas aeruginosa C3719], gi\|254236... gi\|126195804, gi... - gi\|84325462\|ref\|ZP_00973497.1\| COG0498: Threonine synthase [Pseudomonas aeruginosa 2192], gi\|2542424... gi\|218889987, gi... - gi\|218889987\|ref\|YP_002438851.1\| threonine synthase [Pseudomonas aeruginosa LESB58], gi\|218770210\|em... gi\|116051733, gi... - gi\|46164425\|ref\|ZP_00137129.2\| COG0498: Threonine synthase [Pseudomonas aeruginosa UCBPP-PA14], gi\|1...	0.0	[1..469]	[1..469]
gi\|95112211 - gi\|95112211\|emb\|CAK16938.1\| threonine synthase [Pseudomonas entomophila L48] gi\|95112211, gi\|... - gi\|95112211\|emb\|CAK16938.1\| threonine synthase [Pseudomonas entomophila L48], gi\|104783224\|ref\|YP_60...	0.0	[1..469]	[1..469]
gi\|82714908, gi\|... - gi\|82738017\|ref\|ZP_00900858.1\| Threonine synthase [Pseudomonas putida F1], gi\|82714908\|gb\|EAP49981.1...	0.0	[1..469]	[1..469]
gi\|24982942, gi\|... - gi\|26988204\|ref\|NP_743629.1\| threonine synthase [Pseudomonas putida KT2440], gi\|24982942\|gb\|AAN67093...	0.0	[1..469]	[1..469]
gi\|53612515 - ref\|ZP_00342590.1\| COG0498: Threonine synthase [Azotobacter vinelandii] gi\|226945989, gi... - gi\|67156460\|ref\|ZP_00418053.1\| Threonine synthase [Azotobacter vinelandii AvOP], gi\|67086219\|gb\|EAM0...	0.0	[1..469]	[1..469]

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Predicted Domain #1

Region A:
Residues: [1-469]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRYISTRGQA PALNFEDVLL AGLASDGGLY VPENLPRFTL EEIASWVGLP YHELAFRVMR  60
   61 PFVAGSIADA DFKKILEETY GVFAHDAVAP LRQLNGNEWV LELFHGPTLA FKDFALQLLG 120
  121 RLLDHVLAKR GERVVIMGAT SGDTGSAAIE GCRRCDNVDI FIMHPHNRVS EVQRRQMTTI 180
  181 LGDNIHNIAI EGNFDDCQEM VKASFADQGF LKGTRLVAVN SINWARIMAQ IVYYFHAALQ 240
  241 LGAPHRSVAF SVPTGNFGDI FAGYLARNMG LPVSQLIVAT NRNDILHRFM SGNRYDKDTL 300
  301 HPSLSPSMDI MVSSNFERLL FDLHGRNGKA VAELLDAFKA SGKLSVEDQR WTEARKLFDS 360
  361 LAVSDEQTCE TIAEVYRSSG ELLDPHTAIG VRAARECRRS LSVPMVTLGT AHPVKFPEAV 420
  421 EKAGIGQAPA LPAHLADLFE REERCTVLPN ELAKVQAFVS QHGNRGKPL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.39794
Match:	1kl7A
Description:	Threonine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
threonine synthase activity	3.59927532963055	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	2.61572425646119	bayes_pls_golite062009
catalytic activity	2.38994231321972	bayes_pls_golite062009
lyase activity	1.87743897464083	bayes_pls_golite062009
cysteine synthase activity	1.31641967296632	bayes_pls_golite062009
binding	1.19751827446411	bayes_pls_golite062009
tryptophan synthase activity	1.04832999357666	bayes_pls_golite062009
carbon-oxygen lyase activity	0.923824749425553	bayes_pls_golite062009
ammonia-lyase activity	0.476674617721478	bayes_pls_golite062009
L-threonine ammonia-lyase activity	0.37325071016009	bayes_pls_golite062009
protein binding	0.251404253093929	bayes_pls_golite062009
carbon-nitrogen lyase activity	0.249761226675912	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: