YRC Public Data Repository - Protein Structure Prediction

Protein:	RNH2_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	201 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNH2_PSEAE.

Description	E-value	Query Range	Subject Range
RNH2_PSEA8 - Ribonuclease HII OS=Pseudomonas aeruginosa (strain LESB58) GN=rnhB PE=3 SV=1 gi\|107103156 - gi\|107103156\|ref\|ZP_01367074.1\| hypothetical protein PaerPA_01004225 [Pseudomonas aeruginosa PACS2] gi\|84319622, gi\|... - gi\|84319622\|ref\|ZP_00968016.1\| COG0164: Ribonuclease HII [Pseudomonas aeruginosa C3719], gi\|25423655... gi\|84325648, gi\|... - gi\|84325648\|ref\|ZP_00973682.1\| COG0164: Ribonuclease HII [Pseudomonas aeruginosa 2192], gi\|254242340...	3.0E-83	[1..201]	[1..201]
RNH2_PSEA7 - Ribonuclease HII OS=Pseudomonas aeruginosa (strain PA7) GN=rnhB PE=3 SV=1	7.0E-83	[1..201]	[1..201]
gi\|49082728 - gi\|49082728\|gb\|AAT50764.1\| PA3642 [synthetic construct]	1.0E-82	[1..201]	[1..201]
RNH2_PSEAB - Ribonuclease HII OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=rnhB PE=3 SV=1	2.0E-82	[1..201]	[1..201]
gi\|67156398 - gi\|67156398\|ref\|ZP_00417991.1\| Ribonuclease H [Azotobacter vinelandii AvOP] gi\|67086157, gi\|... - gi\|67156398\|ref\|ZP_00417991.1\| Ribonuclease H [Azotobacter vinelandii AvOP], gi\|67086157\|gb\|EAM05627...	3.0E-79	[1..197]	[30..226]
RNH2_VIBPA - Ribonuclease HII OS=Vibrio parahaemolyticus GN=rnhB PE=3 SV=1 RNH2_VIBPA - Ribonuclease HII OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=rnhB PE=3 SV=1	6.0E-79	[5..198]	[17..210]
gi\|91223487, gi\|... - gi\|91223487\|ref\|ZP_01258752.1\| ribonuclease HII [Vibrio alginolyticus 12G01], gi\|91191573\|gb\|EAS7783...	1.0E-78	[5..199]	[17..211]
RNH2_VIBVU - Ribonuclease HII OS=Vibrio vulnificus (strain CMCP6) GN=rnhB PE=3 SV=1 RNH2_VIBVU - Ribonuclease HII OS=Vibrio vulnificus GN=rnhB PE=3 SV=1 RNH2_VIBVY - Ribonuclease HII OS=Vibrio vulnificus (strain YJ016) GN=rnhB PE=3 SV=1	1.0E-78	[5..200]	[12..207]
gi\|254228402, gi... - gi\|75856808\|ref\|ZP_00764431.1\| COG0164: Ribonuclease HII [Vibrio sp. Ex25], gi\|254228402\|ref\|ZP_0492...	1.0E-78	[5..199]	[17..211]
RNH2_PSEU2 - Ribonuclease HII OS=Pseudomonas syringae pv. syringae (strain B728a) GN=rnhB PE=3 SV=1	6.0E-78	[1..200]	[2..201]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLGLDFNLV EDLVAGVDEV GRGPLCGPVV TAAVILDPSR PILGLNDSKK LSEARREALF  60
   61 EEIREKALAW CIARAEVEEI DRLNILHATM LAMQRAVEGL SVIPRLALID GNRCPKLAVP 120
  121 CAPVVKGDSQ VPAIAAASIL AKVSRDREMV ELDRVYPGYG MAGHKGYPTA VHLEALSRLG 180
  181 PTPIHRRSFA PVRELLDVSV Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.0
Match:	2etjA
Description:	Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	3.91517707500372	bayes_pls_golite062009
endoribonuclease activity	3.00008907756136	bayes_pls_golite062009
ribonuclease H activity	2.37346218921366	bayes_pls_golite062009
hydrolase activity	2.30893115816458	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.26022264830742	bayes_pls_golite062009
nuclease activity	1.81796593394339	bayes_pls_golite062009
endonuclease activity	1.79009816048707	bayes_pls_golite062009
catalytic activity	1.62277843225829	bayes_pls_golite062009
exoribonuclease activity	1.48827607538468	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.34153791988846	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.8085201347205	bayes_pls_golite062009
exonuclease activity	0.39213900591465	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	0.13187450705887	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: