YRC Public Data Repository - Protein Structure Prediction

Protein:	LPXH_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	240 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LPXH_PSEAE.

Description	E-value	Query Range	Subject Range
gi\|107101223 - gi\|107101223\|ref\|ZP_01365141.1\| hypothetical protein PaerPA_01002255 [Pseudomonas aeruginosa PACS2] gi\|126166817, gi... - gi\|84321253\|ref\|ZP_00969611.1\| COG2908: Uncharacterized protein conserved in bacteria [Pseudomonas a...	2.0E-68	[1..240]	[1..240]
gi\|49082126 - gi\|49082126\|gb\|AAT50463.1\| PA1792 [synthetic construct]	7.0E-68	[1..240]	[1..240]
LPXH_VIBVY - UDP-2,3-diacylglucosamine hydrolase OS=Vibrio vulnificus (strain YJ016) GN=lpxH PE=3 SV=1	9.0E-68	[1..239]	[1..239]
LPXH_SHISS - UDP-2,3-diacylglucosamine hydrolase OS=Shigella sonnei (strain Ss046) GN=lpxH PE=3 SV=1	1.0E-67	[1..239]	[1..239]
LPXH_VIBVU - UDP-2,3-diacylglucosamine hydrolase OS=Vibrio vulnificus GN=lpxH PE=3 SV=2 LPXH_VIBVU - UDP-2,3-diacylglucosamine hydrolase OS=Vibrio vulnificus (strain CMCP6) GN=lpxH PE=3 SV=2	2.0E-67	[1..239]	[1..239]
gi\|24111892, gi\|... - gi\|24111892\|ref\|NP_706402.1\| UDP-2,3-diacylglucosamine hydrolase [Shigella flexneri 2a str. 301], gi... gi\|75228702, gi\|... - gi\|75228702\|ref\|ZP_00715319.1\| COG2908: Uncharacterized protein conserved in bacteria [Escherichia c... LPXH_SHIF8 - UDP-2,3-diacylglucosamine hydrolase OS=Shigella flexneri serotype 5b (strain 8401) GN=lpxH PE=3 SV=1 LPXH_ECO24 - UDP-2,3-diacylglucosamine hydrolase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=lpxH PE=... LPXH_SHIB3 - UDP-2,3-diacylglucosamine hydrolase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=l... gi\|30040252, gi\|... - gi\|30062008\|ref\|NP_836179.1\| UDP-2,3-diacylglucosamine hydrolase [Shigella flexneri 2a str. 2457T], ... gi\|194437461, gi... - gi\|83587025\|ref\|ZP_00925655.1\| COG2908: Uncharacterized protein conserved in bacteria [Escherichia c... LPXH_SHIBS - UDP-2,3-diacylglucosamine hydrolase OS=Shigella boydii serotype 4 (strain Sb227) GN=lpxH PE=3 SV=1 gi\|193067525, gi... - gi\|75238985\|ref\|ZP_00722967.1\| COG2908: Uncharacterized protein conserved in bacteria [Escherichia c... LPXH_SHIFL - UDP-2,3-diacylglucosamine hydrolase OS=Shigella flexneri GN=lpxH PE=3 SV=1 LPXH_ECO55 - UDP-2,3-diacylglucosamine hydrolase OS=Escherichia coli (strain 55989 / EAEC) GN=lpxH PE=3 SV=1 LPXH_ECO8A - UDP-2,3-diacylglucosamine hydrolase OS=Escherichia coli O8 (strain IAI1) GN=lpxH PE=3 SV=1	3.0E-67	[1..239]	[1..239]
LPXH_AZOVD - UDP-2,3-diacylglucosamine hydrolase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=lpxH PE... gi\|23103557, gi\|... - gi\|67153445\|ref\|ZP_00415190.1\| UDP-2,3-diacylglucosamine hydrolase [Azotobacter vinelandii AvOP], re...	6.0E-67	[1..240]	[1..240]
gi\|89075762, gi\|... - gi\|89075762\|ref\|ZP_01162150.1\| UDP-2,3-diacylglucosamine hydrolase [Photobacterium sp. SKA34], gi\|89...	6.0E-67	[1..238]	[1..238]
LPXH_XANCP - UDP-2,3-diacylglucosamine hydrolase OS=Xanthomonas campestris pv. campestris GN=lpxH PE=3 SV=1 LPXH_XANC8 - UDP-2,3-diacylglucosamine hydrolase OS=Xanthomonas campestris pv. campestris (strain 8004) GN=lpxH P... LPXH_XANCP - UDP-2,3-diacylglucosamine hydrolase OS=Xanthomonas campestris pv. campestris (strain ATCC 33913 / DS...	7.0E-67	[1..240]	[1..247]
gi\|188487603, gi... - gi\|75514642\|ref\|ZP_00736897.1\| COG2908: Uncharacterized protein conserved in bacteria [Escherichia c... LPXH_ECOSE - UDP-2,3-diacylglucosamine hydrolase OS=Escherichia coli (strain SE11) GN=lpxH PE=3 SV=1 LPXH_ECOSM - UDP-2,3-diacylglucosamine hydrolase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=lpxH PE=3 SV=1	7.0E-67	[1..239]	[1..239]

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Predicted Domain #1

Region A:
Residues: [1-240]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVLFISDLH LEAERPDITR AFLSFLDERA RRAEALYILG DFFEAWIGDD GMDAFQRSIA  60
   61 QSLRQVADGG TRIYLMHGNR DFLIGKAFCR EAGCTLLPDP SVIDLYGEPV LLMHGDSLCT 120
  121 RDEAYMRLRR WLRNPLTLWV LRHLPLATRH KLARKLRKES RAQTRMKAVD IIDVTPEEVP 180
  181 RVMRGHGVRT LIHGHTHRPA EHPLDIDGQP ARRIVLGDWD RQGWALEIDA NGHRQAPFPL 240
  241

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.522879
Match:	1ii7A
Description:	Mre11
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39852585255405	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.08477762279171	bayes_pls_golite062009
phosphoprotein phosphatase activity	1.05109559862153	bayes_pls_golite062009
protein serine/threonine phosphatase activity	0.877022343553428	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.762880369401283	bayes_pls_golite062009
phosphatase activity	0.638806808750323	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: