YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11351998
Organism:	Pseudomonas aeruginosa
Length:	237 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11351998.

Description	E-value	Query Range	Subject Range
gi\|94417993, gi\|... - gi\|94417993\|ref\|ZP_01297809.1\| hypothetical protein PaerP_01000142 [Pseudomonas aeruginosa PA7], gi\|...	5.0E-36	[1..237]	[1..237]
gi\|49081996 - gi\|49081996\|gb\|AAT50398.1\| PA0906 [synthetic construct]	1.0E-35	[1..237]	[1..237]
gi\|68544779, gi\|... - gi\|68544779\|ref\|ZP_00584383.1\| Helix-turn-helix motif:Peptidase S24, S26A and S26B [Shewanella balti...	2.0E-32	[2..237]	[3..233]
gi\|254222472, gi... - gi\|75822998\|ref\|ZP_00752538.1\| COG2932: Predicted transcriptional regulator [Vibrio cholerae RC385],... gi\|229528221, gi... - gi\|229528221\|ref\|ZP_04417612.1\| hypothetical protein VCG_001301 [Vibrio cholerae 12129(1)], gi\|22933... tr\|D7HBR5\|D7HBR5... - Repressor protein CI OS=Vibrio cholerae GN=cI PE=4 SV=1, HTH-type transcriptional regulator PrtR OS=...	3.0E-32	[2..237]	[5..237]
gi\|117609813, gi... - gi\|69258750\|ref\|ZP_00607262.1\| Helix-turn-helix motif:Peptidase S24, S26A and S26B [Magnetococcus sp...	3.0E-32	[2..236]	[32..263]
gi\|160875134, gi... - gi\|160875134\|ref\|YP_001554450.1\| putative phage repressor [Shewanella baltica OS195], gi\|160860656\|g...	4.0E-32	[2..237]	[3..233]
gi\|91716618, gi\|... - gi\|91794616\|ref\|YP_564267.1\| transciptional regulator [Shewanella denitrificans OS217], gi\|91716618\|...	2.0E-31	[5..237]	[4..229]
gi\|115589560, gi... - gi\|53727242\|ref\|ZP_00141067.2\| COG2932: Predicted transcriptional regulator [Pseudomonas aeruginosa ...	2.0E-30	[2..236]	[11..246]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELKDRIKAA RKHAHLSQVQ LAQAVGMTQT SISDLERGKS RATSFVAQIA GACGVNPLWL  60
   61 AEGRGEMLAE RGQANAGPNA SWLGAVESWD DETPLDADEI ELPFYKEIEL SGGKGSTVIL 120
  121 QTGGRKLRFG KYTLRKKNID PASAACVTVS GNSMEPVLPD GSTVGVDTSA RTIKDGDMYA 180
  181 FDHDGQLRVK LLYRLPGGGL RIRSFNSDEH PDERYEPQEA AEHINVIGRV FWYSVLV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.39794
Match:	1jhfA
Description:	LexA repressor, N-terminal DNA-binding domain; LexA C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	2.13370593570418	bayes_pls_golite062009
nucleic acid binding	1.55694924162006	bayes_pls_golite062009
DNA binding	1.42504441648262	bayes_pls_golite062009
binding	1.26570271545147	bayes_pls_golite062009
transcription factor activity	0.911559854968835	bayes_pls_golite062009
protein binding	0.378066881516827	bayes_pls_golite062009
catalytic activity	0.0451617952658021	bayes_pls_golite062009
transcription repressor activity	0.0123300332408647	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: