YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11347535
Organism:	Pseudomonas aeruginosa
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11347535.

Description	E-value	Query Range	Subject Range
gi\|126171085, gi... - gi\|84316708\|ref\|ZP_00965177.1\| COG2513: PEP phosphonomutase and related enzymes [Pseudomonas aerugin...	5.0E-87	[1..298]	[1..298]
gi\|71737165, gi\|... - gi\|71737165\|ref\|YP_274275.1\| 2-methylisocitrate lyase [Pseudomonas syringae pv. phaseolicola 1448A],...	2.0E-86	[1..296]	[1..296]
gi\|70729244, gi\|... - gi\|70729244\|ref\|YP_258980.1\| 2-methylisocitrate lyase [Pseudomonas fluorescens Pf-5], gi\|68343543\|gb...	3.0E-86	[1..296]	[1..296]
tr\|Q883R3\|Q883R3... - Methylisocitrate lyase OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=prpB PE=4 SV=1 gi\|28869487, gi\|... - gi\|28869487\|ref\|NP_792106.1\| 2-methylisocitrate lyase [Pseudomonas syringae pv. tomato str. DC3000],... gi\|213927079, gi... - gi\|213968099\|ref\|ZP_03396244.1\| methylisocitrate lyase [Pseudomonas syringae pv. tomato T1], gi\|2139...	1.0E-85	[1..296]	[1..296]
gi\|46915335, gi\|... - gi\|54301915\|ref\|YP_131908.1\| 2-methylisocitrate lyase [Photobacterium profundum SS9], gi\|46915335\|em...	2.0E-85	[6..295]	[1..289]
gi\|66045325, gi\|... - gi\|66045325\|ref\|YP_235166.1\| 2-methylisocitrate lyase [Pseudomonas syringae pv. syringae B728a], gi\|...	2.0E-85	[1..296]	[1..296]
gi\|77381994, gi\|... - gi\|77457991\|ref\|YP_347496.1\| 2-methylisocitrate lyase [Pseudomonas fluorescens Pf0-1], gi\|77381994\|g...	3.0E-85	[1..296]	[1..296]
gi\|90409987, gi\|... - gi\|90409987\|ref\|ZP_01218004.1\| putative carboxyphosphonoenolpyruvate phosphonomutase [Photobacterium...	7.0E-85	[6..295]	[1..289]
gi\|17429018 - gi\|17429018\|emb\|CAD15702.1\| probable carboxyvinyl-carboxyphosphonate phosphorylmutase protein [Ralst... gi\|17546719 - gi\|17546719\|ref\|NP_520121.1\| 2-methylisocitrate lyase [Ralstonia solanacearum GMI1000]	1.0E-83	[4..296]	[10..302]
gi\|207742797, gi... - gi\|207742797\|ref\|YP_002259189.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase protein [Ralstonia... gi\|83748077, gi\|... - gi\|83748077\|ref\|ZP_00945106.1\| Methylisocitrate lyase [Ralstonia solanacearum UW551], gi\|83725263\|gb...	2.0E-83	[4..296]	[5..297]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQTSLTPGQ RFREAVATEH PLQVVGTINA NHALLAKRAG FKAIYLSGGG VAAGSLGLPD  60
   61 LGISGLDDVL TDVRRITDVC DLPLLVDVDT GFGSSAFNVA RTVKSMIKFG AAAMHIEDQV 120
  121 GAKRCGHRPN KEIVSQQEMV DRIKAAVDAR SDDSFVIMAR TDALAVEGLQ AAIDRACACV 180
  181 EAGADMIFPE AMTELAMYKE FAAAVKVPVL ANITEFGATP LFTTDELASA DVSLVLYPLS 240
  241 AFRAMNKAAE NVYTAIRRDG TQKNVIDTMQ TRMELYDRID YHSFEQKLDA LFAQKKNA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.522879
Match:	1o5qA
Description:	Crystal Structure of Pyruvate and Mg2+ bound 2-methylisocitrate lyase (PrpB) from Salmonella typhimurium
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.96882793316847	bayes_pls_golite062009
methylisocitrate lyase activity	2.09739770469711	bayes_pls_golite062009
citrate (pro-3S)-lyase activity	0.86095690814621	bayes_pls_golite062009
lyase activity	0.70986506551964	bayes_pls_golite062009
transferase activity	0.5687068385416	bayes_pls_golite062009
oxo-acid-lyase activity	0.404868472347919	bayes_pls_golite062009
carbon-carbon lyase activity	0.36217387205482	bayes_pls_golite062009
carboxyvinyl-carboxyphosphonate phosphorylmutase activity	0.2132734143313	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: