YRC Public Data Repository - Protein Structure Prediction

Protein:	TRPB_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	402 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRPB_PSEAE.

Description	E-value	Query Range	Subject Range
TRPB_PARDP - Tryptophan synthase beta chain OS=Paracoccus denitrificans (strain Pd 1222) GN=trpB PE=3 SV=1	0.0	[1..397]	[6..405]
TRPB_AZOVD - Tryptophan synthase beta chain OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=trpB PE=3 SV... gi\|67154984, gi\|... - gi\|67154984\|ref\|ZP_00416729.1\| Tryptophan synthase, beta chain [Azotobacter vinelandii AvOP], ref\|ZP...	0.0	[2..401]	[4..403]
gi\|115588978, gi... - gi\|53726923\|ref\|ZP_00347731.1\| COG0133: Tryptophan synthase beta chain [Pseudomonas aeruginosa UCBPP...	0.0	[1..402]	[1..402]
gi\|151616 - gi\|151616\|gb\|AAA88462.1\| tryptophan synthase beta subunit	0.0	[1..402]	[1..402]
gi\|154245637, gi... - gi\|89360657\|ref\|ZP_01198475.1\| Tryptophan synthase, beta chain [Xanthobacter autotrophicus Py2], gi\|...	0.0	[1..402]	[4..405]
TRPB_PSEF5 - Tryptophan synthase beta chain OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=trpB PE=3 ...	0.0	[4..398]	[6..400]
gi\|71739840, gi\|... - gi\|71839674\|ref\|ZP_00679418.1\| Tryptophan synthase, beta chain [Pelobacter propionicus DSM 2379], gi...	0.0	[5..397]	[1..393]
gi\|77970857, gi\|... - gi\|78062972\|ref\|YP_372880.1\| tryptophan synthase subunit beta [Burkholderia sp. 383], gi\|77970857\|gb...	0.0	[5..400]	[2..397]
TRPB_OCEIH - Tryptophan synthase beta chain OS=Oceanobacillus iheyensis GN=trpB PE=3 SV=1 TRPB_OCEIH - Tryptophan synthase beta chain OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954...	0.0	[1..399]	[1..398]
gi\|152988472, gi... - gi\|94417314\|ref\|ZP_01297133.1\| hypothetical protein PaerP_01001114 [Pseudomonas aeruginosa PA7], gi\|...	0.0	[1..402]	[1..402]

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Predicted Domain #1

Region A:
Residues: [1-402]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSYRNGPDA KGLFGRFGGQ YVAETLMPLI LDLAREYEKA KDDPAFQEEL AYFQRDYVGR  60
   61 PSPLYFAERL TEHCGGAKIY LKREELNHTG AHKINNCIGQ ILLARRMGKK RIIAETGAGM 120
  121 HGVATATVAA RFGLQCVIYM GTTDIDRQQA NVFRMKLLGA EVIPVTAGTG TLKDAMNEAL 180
  181 RDWVTNVDST FYLIGTVAGP HPYPAMVRDF QAVIGKETRE QLAEKEGRLP DSLVACIGGG 240
  241 SNAMGLFHPF LDDAGVQIVG VEAAGHGIDT GKHAASLNGG VPGVLHGNRT FLLQDADGQI 300
  301 IDAHSISAGL DYPGIGPEHA WLHDTGRVEY TSITDDEALE AFHTCCRLEG IIPALESSHA 360
  361 LAEVFKRAPS LPKEHIMVVN LSGRGDKDMQ TVMHHMQQES KA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	124.0
Match:	1v8zA
Description:	X-ray crystal structure of the Tryptophan Synthase b2 Subunit from Hyperthermophile, Pyrococcus furiosus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
tryptophan synthase activity	3.77857340461162	bayes_pls_golite062009
catalytic activity	2.76038225023173	bayes_pls_golite062009
lyase activity	2.54165185299539	bayes_pls_golite062009
carbon-oxygen lyase activity, acting on phosphates	1.82148750304597	bayes_pls_golite062009
cysteine synthase activity	1.54736143994982	bayes_pls_golite062009
carbon-oxygen lyase activity	1.52790731142158	bayes_pls_golite062009
ammonia-lyase activity	0.943946746392831	bayes_pls_golite062009
threonine synthase activity	0.86525519885835	bayes_pls_golite062009
carbon-nitrogen lyase activity	0.8463142805916	bayes_pls_golite062009
L-threonine ammonia-lyase activity	0.57533596285038	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: