YRC Public Data Repository - Protein Structure Prediction

Protein:	EFTS_AQUAE
Organism:	Aquifex aeolicus VF5
Length:	290 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EFTS_AQUAE.

Description	E-value	Query Range	Subject Range
gi\|133727060, gi... - gi\|254872766\|ref\|ZP_05245476.1\| elongation factor Ts [Listeria monocytogenes FSL N1-017], gi\|1531673... EFTS_LISMC - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=tsf PE=3 SV=1 EFTS_LISMH - Elongation factor Ts OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=tsf PE=3 SV=1 gi\|254852281 - gi\|254852281\|ref\|ZP_05241629.1\| elongation factor Ts [Listeria monocytogenes FSL R2-503] EFTS_LISMC - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=tsf PE=3 SV=1 gi\|254824282 - gi\|254824282\|ref\|ZP_05229283.1\| elongation factor Ts [Listeria monocytogenes FSL J1-194] gi\|255521679 - gi\|255521679\|ref\|ZP_05388916.1\| elongation factor Ts [Listeria monocytogenes FSL J1-175] gi\|254992981 - gi\|254992981\|ref\|ZP_05275171.1\| elongation factor Ts [Listeria monocytogenes FSL J2-064] EFTS_LISMF - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tsf PE=3 SV=1 gi\|47093766, gi\|... - gi\|47093766\|ref\|ZP_00231515.1\| translation elongation factor Ts [Listeria monocytogenes str. 4b H785...	343.0	[0..2]	[289..1]
gi\|25299529 - gi\|25299529\|pir\|\|F97526 elongation factor TS (ef-ts) [imported] - Agrobacterium tumefaciens (strain ... gi\|15156441, gi\|... - gi\|15888701\|ref\|NP_354382.1\| elongation factor Ts [Agrobacterium tumefaciens str. C58], gi\|15156441\|...	342.0	[0..2]	[289..72]
gi\|224501402 - gi\|224501402\|ref\|ZP_03669709.1\| elongation factor Ts [Listeria monocytogenes FSL R2-561] gi\|224499238 - gi\|224499238\|ref\|ZP_03667587.1\| elongation factor Ts [Listeria monocytogenes Finland 1988] EFTS_LISMO - Elongation factor Ts OS=Listeria monocytogenes GN=tsf PE=3 SV=1 EFTS_LISMO - Elongation factor Ts OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=tsf PE=... gi\|255026415 - gi\|255026415\|ref\|ZP_05298401.1\| elongation factor Ts [Listeria monocytogenes FSL J2-003] gi\|254936658 - gi\|254936658\|ref\|ZP_05268355.1\| elongation factor Ts [Listeria monocytogenes F6900] gi\|254898176, gi... - gi\|254898176\|ref\|ZP_05258100.1\| elongation factor Ts [Listeria monocytogenes J0161], gi\|153186011\|re... gi\|153191101, gi... - gi\|254912331\|ref\|ZP_05262343.1\| elongation factor Ts [Listeria monocytogenes J2818], gi\|153191101\|re... gi\|127633591, gi... - gi\|254832060\|ref\|ZP_05236715.1\| elongation factor Ts [Listeria monocytogenes 10403S], gi\|153196708\|r... gi\|254829461, gi... - gi\|254829461\|ref\|ZP_05234148.1\| elongation factor Ts [Listeria monocytogenes FSL N3-165], gi\|1531748...	342.0	[0..2]	[289..1]
EFTS_LISIN - Elongation factor Ts OS=Listeria innocua GN=tsf PE=3 SV=1 EFTS_LISIN - Elongation factor Ts OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=tsf PE=3 SV=1	342.0	[0..2]	[289..1]
gi\|114704875, gi... - gi\|114704875\|ref\|ZP_01437783.1\| translation elongation factor Ts protein [Fulvimarina pelagi HTCC250...	339.0	[0..3]	[289..17]
EFTS_NOSP7 - Elongation factor Ts OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=tsf PE=3 SV=1	337.0	[0..2]	[289..1]
EFTS_NOSS1 - Elongation factor Ts OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=tsf PE=3 SV=1 gi\|25299530 - pir\|\|AG2404 translation elongation factor Ts [imported] - Nostoc sp. (strain PCC 7120)	337.0	[0..2]	[289..1]
EFTS_MAGMM - Elongation factor Ts OS=Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) GN=tsf PE=3 ... sp\|A0L8Q6\|EFTS_MAGMM - Elongation factor Ts OS=Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1) GN=tsf PE=3 ...	337.0	[0..3]	[289..1]
EFTS_NITOC - Elongation factor Ts OS=Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848) GN=tsf PE=3 SV=1 gi\|207089820 - gi\|207089820\|gb\|EDZ67091.1\| translation elongation factor Ts [Nitrosococcus oceani AFC27] gi\|224410166, gi... - gi\|254433487\|ref\|ZP_05046995.1\| translation elongation factor Ts [Nitrosococcus oceani AFC27], gi\|22...	336.0	[0..3]	[289..1]
EFTS_ANAVT - Elongation factor Ts OS=Anabaena variabilis (strain ATCC 29413 / PCC 7937) GN=tsf PE=3 SV=1	336.0	[0..2]	[289..1]

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Predicted Domain #1

Region A:
Residues: [1-290]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRMAVSMEDV KKLREMTGAG MLDCKKALEE AGGDIEKAKE ILRVKGLAKA EKKAGRETKE  60
   61 GLIYVIVSED RKKGAMIELN CETDFVARNE EFRKLAERIT RHILEKDENK NKSGEGSEIL 120
  121 SQELYDEPGK TVETLIKEAI AKIGENIRLS RYCRYDTEDY LHSYVHGGGR IGVLLDFKAP 180
  181 ELNDQVLRLV QDVAMQIAAM RPEYVRIEDI PQEVLERERR ILREQALQEG KPEHIVDKIV 240
  241 EGKLKKFYQE KVLLEQPFIK EEKKQVKDVI KESGLNVEIK RFCRFELGGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.0
Match:	1efuB
Description:	Elongation factor Ts (EF-Ts), N-terminal domain; Elongation factor Ts (EF-Ts), dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation elongation factor activity	7.45583793023677	bayes_pls_golite062009
translation regulator activity	3.96278094372195	bayes_pls_golite062009
translation factor activity, nucleic acid binding	3.9473033844258	bayes_pls_golite062009
nucleic acid binding	3.24631360795453	bayes_pls_golite062009
binding	2.60366518310248	bayes_pls_golite062009
ubiquitin binding	0.83381750627184	bayes_pls_golite062009
small conjugating protein binding	0.643709242447801	bayes_pls_golite062009
transcription regulator activity	0.43285087811192	bayes_pls_golite062009
DNA binding	0.262676519883369	bayes_pls_golite062009
catalytic activity	0.25774924710417	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: