YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7451293
Organism:	Aquifex aeolicus
Length:	136 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7451293.

Description	E-value	Query Range	Subject Range
gi\|17430370 - gi\|17430370\|emb\|CAD17135.1\| probable transcription regulator protein [Ralstonia solanacearum GMI1000... gi\|17548064 - gi\|17548064\|ref\|NP_521466.1\| transcription regulator protein [Ralstonia solanacearum GMI1000]	113.0	[0..9]	[117..16]
gi\|69133946, gi\|... - gi\|69298712\|ref\|ZP_00620841.1\| regulatory protein, MerR [Silicibacter sp. TM1040], gi\|69133946\|gb\|EA...	109.0	[0..1]	[112..147]
HMRR_SINMW - HTH-type transcriptional regulator HmrR OS=Sinorhizobium medicae (strain WSM419) GN=hmrR PE=1 SV=1 HMRR_RHIME - HTH-type transcriptional regulator hmrR - Rhizobium meliloti (Sinorhizobium meliloti)	108.0	[0..8]	[117..1]
gi\|76578268, gi\|... - gi\|76808815\|ref\|YP_333781.1\| MerR family transcriptional regulator [Burkholderia pseudomallei 1710b]...	108.0	[0..4]	[120..100]
gi\|72120470, gi\|... - gi\|73543057\|ref\|YP_297577.1\| MerR family transcriptional regulator [Ralstonia eutropha JMP134], gi\|7...	107.0	[0..8]	[127..1]
gi\|76884528, gi\|... - gi\|77166214\|ref\|YP_344739.1\| Hg(II)-responsive transcriptional regulator [Nitrosococcus oceani ATCC ... gi\|207088140 - gi\|207088140\|gb\|EDZ65412.1\| Hg(II)-responsive transcriptional regulator [Nitrosococcus oceani AFC27] gi\|224408486, gi... - gi\|254435029\|ref\|ZP_05048536.1\| Hg(II)-responsive transcriptional regulator [Nitrosococcus oceani AF...	107.0	[0..1]	[119..1]
gi\|119374841, gi... - gi\|69936174\|ref\|ZP_00631034.1\| regulatory protein, MerR [Paracoccus denitrificans PD1222], gi\|691525...	107.0	[0..7]	[114..1]
gi\|134295875, gi... - gi\|67543761\|ref\|ZP_00421692.1\| regulatory protein, MerR [Burkholderia vietnamiensis G4], gi\|67534929...	106.0	[0..8]	[136..14]
gi\|85670045, gi\|... - gi\|85705620\|ref\|ZP_01036718.1\| Cu(I)-responsive transcriptional regulator [Roseovarius sp. 217], gi\|...	106.0	[0..8]	[113..1]
gi\|115281821, gi... - gi\|74019152\|ref\|ZP_00689770.1\| regulatory protein, MerR [Burkholderia ambifaria AMMD], gi\|72608139\|g...	106.0	[0..8]	[136..14]

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Predicted Domain #1

Region A:
Residues: [1-136]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKRKAYYTI GVVAKMYNIH PQTLRLYERE GLLKPSRSEG NTRLYTDEDL ERLEFILFLT  60
   61 RELGVNLAGV DIILNLKEQM EQMQKQIDQL MEFIQNELSK LQGEAYQRAI VKVPKTKVMK 120
  121 FEEVIVSRQK KSDEEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	15.522879
Match:	1exiA
Description:	Transcription activator BmrR; Multidrug-binding domain of transcription activator BmrR
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.40729334364274	bayes_pls_golite062009
DNA binding	2.05877861880033	bayes_pls_golite062009
nucleic acid binding	1.99474406643819	bayes_pls_golite062009
transcription factor activity	1.84836087644732	bayes_pls_golite062009
binding	1.32395331736751	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: