YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|17943390, gi\|...
Organism:	Pyrococcus horikoshii
Length:	180 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|17943390, gi|....

Description	E-value	Query Range	Subject Range
gi\|5458403, gi\|7... - pir\|\|F75073 pyrazinamidase/nicotinamidase PAB1720 - Pyrococcus abyssi (strain Orsay), gi\|5458403\|em... gi\|5458403, gi\|1... - gi\|5458403\|emb\|CAB49891.1\| Amidase related to nicotinamidase [Pyrococcus abyssi GE5], gi\|14521185\|re...	209.0	[0..1]	[180..1]
gi\|57159909, gi\|... - gi\|57641585\|ref\|YP_184063.1\| nicotinamidase [Thermococcus kodakarensis KOD1], gi\|57159909\|dbj\|BAD858...	206.0	[0..1]	[178..1]
gi\|18977477, gi\|... - gi\|18977477\|ref\|NP_578834.1\| pyrazinamidase/nicotinamidase pxnc [Pyrococcus furiosus DSM 3638], gi\|1...	201.0	[0..1]	[178..1]
gi\|82702035, gi\|... - gi\|82702035\|ref\|YP_411601.1\| isochorismatase hydrolase [Nitrosospira multiformis ATCC 25196], gi\|824...	175.0	[0..5]	[178..10]
gi\|15606301, gi\|... - gi\|2983496\|gb\|AAC07074.1\| pyrazinamidase/nicotinamidase [Aquifex aeolicus VF5], gi\|15606301\|ref\|NP_2... gi\|7445162 - pir\|\|B70386 pyrazinamidase/nicotinamidase - Aquifex aeolicus	173.0	[0..3]	[178..8]
gi\|19886895, gi\|... - gi\|20093942\|ref\|NP_613789.1\| nicotinamidase-like amidase [Methanopyrus kandleri AV19], gi\|19886895\|g...	173.0	[0..5]	[178..3]
gi\|53803102, gi\|... - gi\|53803102\|ref\|YP_115158.1\| pyrazinamidase/nicotinamidase, putative [Methylococcus capsulatus str. ...	172.0	[0..5]	[176..15]
gi\|27381262, gi\|... - gi\|27381262\|ref\|NP_772791.1\| isochorismatase family protein [Bradyrhizobium japonicum USDA 110], gi\|...	167.0	[0..3]	[176..23]
gi\|86606564, gi\|... - gi\|86606564\|ref\|YP_475327.1\| isochorismatase family protein [Synechococcus sp. JA-3-3Ab], gi\|8655510... gi\|86606564 - gi\|86606564\|ref\|YP_475327.1\| isochorismatase family protein [Cyanobacteria bacterium Yellowstone A-P...	164.0	[0..3]	[176..22]
gi\|7429496 - pir\|\|G69518 isochorismatase (entB) homolog - Archaeoglobus fulgidus gi\|11499734, gi\|... - gi\|2648379\|gb\|AAB89104.1\| isochorismatase (entB) [Archaeoglobus fulgidus DSM 4304], gi\|11499734\|ref\|...	163.0	[0..5]	[178..3]

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Predicted Domain #1

Region A:
Residues: [1-180]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEEALIVVD MQRDFMPGGA LPVPEGDKII PKVNEYIRKF KEKGALIVAT RDWHPENHIS  60
   61 FRERGGPWPR HCVQNTPGAE FVVDLPEDAV IISKATEPDK EAYSGFEGTD LAKILRGNGV 120
  121 KRVYICGVAT EYCVRATALD ALKHGFEVYL LRDAVKGIKP EDEERALEEM KSRGIKIVQF 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.69897
Match:	1ilwA
Description:	Pyrazinamidase/nicotinamidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinamidase activity	2.590271821288	bayes_pls_golite062009
binding	1.80707112356899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1.33901087189475	bayes_pls_golite062009
catalytic activity	0.992051062697807	bayes_pls_golite062009
protein binding	0.343971697425971	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: