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View Structure Prediction Details

Protein: gi|50914988, gi|...
Organism: Streptococcus pyogenes MGAS10394
Length: 565 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50914988, gi|....

Description E-value Query
Range
Subject
Range
gi|21905402, gi|... - gi|21911190|ref|NP_665458.1| PTS system, lactose-specific IIBC component [Streptococcus pyogenes MGA...
gi|28896564, gi|... - gi|28896564|ref|NP_802914.1| PTS system, lactose-specific IIBC component [Streptococcus pyogenes SSI...
350.0 [0..1] [565..1]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGLIAQIEK GKPFFEKISR NIYLRAIRDG FIAGMPVILF SSIFILIAYV PNAWGFHWSK  60
   61 DIENLLMTPY NYSMGILGLF VAGTTAKALT DSMNRSLPST NQINFISTML AAIVGFLLM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [120-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AANPAKDGGF LTGFMGTKGL LTAFIAAFIT VNVYKVCVKN NVTIRMPEEV PPNISQVFKD  60
   61 LIPFTLSVVL LYVIELIVHS TLGVNVAESI GKLLAPLFQA A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [221-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGYVGITIIF GAFALFWFVG IHGPSIVEPA IAAITYANAE TNLQLLQAGE HADKILTSGT  60
   61 QMFIVTMGGT GATLVVPFMF MWLTKSKRNK AIGRASVVPT FFGVNEPILF GAPLVLNPIF 120
  121 FIPFILAPIV NVWIFKFFID TLGMNSFTAN LPWTTPAPLG LILGTNFQVL AFILAALLIV 180
  181 VDVIIY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [407-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPFLKVYDEQ ILAEEAAGTN SSDVLKEKVA ANFDTKKADA ILEKSAAKET KEITDQTNVL  60
   61 VLCAGGGTSG LLANALNKAA KEYGAPVTAA AGSYGAHREI LPQYQLVILA PQVASNYEDM 120
  121 KVETDKLDIK LAKTEGAQYI KLTRDGQGAL DFVKEQMEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 1ggrA
Description: Glucose-specific factor III (glsIII)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity 3.63095060058431 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.68179471492286 bayes_pls_golite062009
binding 0.587569240975485 bayes_pls_golite062009
transporter activity 0.416424316903358 bayes_pls_golite062009
transmembrane transporter activity 0.245554686788991 bayes_pls_golite062009
active transmembrane transporter activity 0.00716122418063003 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle