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View Structure Prediction Details

Protein: gi|50914988, gi|...
Organism: Streptococcus pyogenes MGAS10394
Length: 565 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|50914988, gi|....

Description E-value Query
Range
Subject
Range
gi|21905402, gi|... - gi|21911190|ref|NP_665458.1| PTS system, lactose-specific IIBC component [Streptococcus pyogenes MGA...
gi|28896564, gi|... - gi|28896564|ref|NP_802914.1| PTS system, lactose-specific IIBC component [Streptococcus pyogenes SSI...
350.0 [0..1] [565..1]

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Predicted Domain #1
Region A:
Residues: [1-119]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGLIAQIEK GKPFFEKISR NIYLRAIRDG FIAGMPVILF SSIFILIAYV PNAWGFHWSK  60
   61 DIENLLMTPY NYSMGILGLF VAGTTAKALT DSMNRSLPST NQINFISTML AAIVGFLLM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [120-220]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AANPAKDGGF LTGFMGTKGL LTAFIAAFIT VNVYKVCVKN NVTIRMPEEV PPNISQVFKD  60
   61 LIPFTLSVVL LYVIELIVHS TLGVNVAESI GKLLAPLFQA A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [221-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGYVGITIIF GAFALFWFVG IHGPSIVEPA IAAITYANAE TNLQLLQAGE HADKILTSGT  60
   61 QMFIVTMGGT GATLVVPFMF MWLTKSKRNK AIGRASVVPT FFGVNEPILF GAPLVLNPIF 120
  121 FIPFILAPIV NVWIFKFFID TLGMNSFTAN LPWTTPAPLG LILGTNFQVL AFILAALLIV 180
  181 VDVIIY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [407-565]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPFLKVYDEQ ILAEEAAGTN SSDVLKEKVA ANFDTKKADA ILEKSAAKET KEITDQTNVL  60
   61 VLCAGGGTSG LLANALNKAA KEYGAPVTAA AGSYGAHREI LPQYQLVILA PQVASNYEDM 120
  121 KVETDKLDIK LAKTEGAQYI KLTRDGQGAL DFVKEQMEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.39794
Match: 1ggrA
Description: Glucose-specific factor III (glsIII)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity 3.63095060058431 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.68179471492286 bayes_pls_golite062009
binding 0.587569240975485 bayes_pls_golite062009
transporter activity 0.416424316903358 bayes_pls_golite062009
transmembrane transporter activity 0.245554686788991 bayes_pls_golite062009
active transmembrane transporter activity 0.00716122418063003 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle