YRC Public Data Repository - Protein Structure Prediction

Protein:	EFTS_STAAS
Organism:	Staphylococcus aureus subsp. aureus MSSA476
Length:	293 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EFTS_STAAS.

Description	E-value	Query Range	Subject Range
gi\|133727060, gi... - gi\|254872766\|ref\|ZP_05245476.1\| elongation factor Ts [Listeria monocytogenes FSL N1-017], gi\|1531673... EFTS_LISMC - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=tsf PE=3 SV=1 EFTS_LISMH - Elongation factor Ts OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=tsf PE=3 SV=1 gi\|254852281 - gi\|254852281\|ref\|ZP_05241629.1\| elongation factor Ts [Listeria monocytogenes FSL R2-503] EFTS_LISMC - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=tsf PE=3 SV=1 gi\|254824282 - gi\|254824282\|ref\|ZP_05229283.1\| elongation factor Ts [Listeria monocytogenes FSL J1-194] gi\|255521679 - gi\|255521679\|ref\|ZP_05388916.1\| elongation factor Ts [Listeria monocytogenes FSL J1-175] gi\|254992981 - gi\|254992981\|ref\|ZP_05275171.1\| elongation factor Ts [Listeria monocytogenes FSL J2-064] EFTS_LISMF - Elongation factor Ts OS=Listeria monocytogenes serotype 4b (strain F2365) GN=tsf PE=3 SV=1 gi\|47093766, gi\|... - gi\|47093766\|ref\|ZP_00231515.1\| translation elongation factor Ts [Listeria monocytogenes str. 4b H785...	400.0	[0..1]	[293..1]
gi\|224501402 - gi\|224501402\|ref\|ZP_03669709.1\| elongation factor Ts [Listeria monocytogenes FSL R2-561] gi\|224499238 - gi\|224499238\|ref\|ZP_03667587.1\| elongation factor Ts [Listeria monocytogenes Finland 1988] EFTS_LISMO - Elongation factor Ts OS=Listeria monocytogenes GN=tsf PE=3 SV=1 EFTS_LISMO - Elongation factor Ts OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=tsf PE=... gi\|255026415 - gi\|255026415\|ref\|ZP_05298401.1\| elongation factor Ts [Listeria monocytogenes FSL J2-003] gi\|254936658 - gi\|254936658\|ref\|ZP_05268355.1\| elongation factor Ts [Listeria monocytogenes F6900] gi\|254898176, gi... - gi\|254898176\|ref\|ZP_05258100.1\| elongation factor Ts [Listeria monocytogenes J0161], gi\|153186011\|re... gi\|153191101, gi... - gi\|254912331\|ref\|ZP_05262343.1\| elongation factor Ts [Listeria monocytogenes J2818], gi\|153191101\|re... gi\|127633591, gi... - gi\|254832060\|ref\|ZP_05236715.1\| elongation factor Ts [Listeria monocytogenes 10403S], gi\|153196708\|r... gi\|254829461, gi... - gi\|254829461\|ref\|ZP_05234148.1\| elongation factor Ts [Listeria monocytogenes FSL N3-165], gi\|1531748...	399.0	[0..1]	[293..1]
EFTS_LISIN - Elongation factor Ts OS=Listeria innocua GN=tsf PE=3 SV=1 EFTS_LISIN - Elongation factor Ts OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=tsf PE=3 SV=1	398.0	[0..1]	[293..1]
EFTS_STAS1 - Elongation factor Ts OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 2...	397.0	[0..3]	[293..2]
gi\|89098611, gi\|... - gi\|89098611\|ref\|ZP_01171493.1\| elongation factor Ts [Bacillus sp. NRRL B-14911], gi\|89086573\|gb\|EAR6...	389.0	[0..3]	[293..2]
EFTS_BACSK - Elongation factor Ts OS=Bacillus clausii (strain KSM-K16) GN=tsf PE=3 SV=1	387.0	[0..3]	[293..2]
EFTS_STAA2 - Elongation factor Ts OS=Staphylococcus aureus (strain JH1) GN=tsf PE=3 SV=1 gi\|255006044 - gi\|255006044\|ref\|ZP_05144645.2\| elongation factor Ts [Staphylococcus aureus subsp. aureus Mu50-omega... EFTS_STAA9 - Elongation factor Ts OS=Staphylococcus aureus (strain JH9) GN=tsf PE=3 SV=1 gi\|269202874\|ref... - elongation factor Ts [Staphylococcus aureus subsp. aureus ED98] EFTS_STAAN - Elongation factor Ts OS=Staphylococcus aureus (strain N315) GN=tsf PE=1 SV=1 EFTS_STAAM - Elongation factor Ts OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=tsf PE=3 SV=1 EFTS_STAA1 - Elongation factor Ts OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=tsf PE=3 SV=1 gi\|25299520 - pir\|\|D89899 elongation factor TS [imported] - Staphylococcus aureus (strain N315) gi\|253315613 - gi\|253315613\|ref\|ZP_04838826.1\| elongation factor Ts [Staphylococcus aureus subsp. aureus str. CF-Ma...	384.0	[0..1]	[293..1]
gi\|229329602, gi... - gi\|229499544\|ref\|ZP_04393228.1\| translation elongation factor Ts [Geobacillus sp. Y412MC52], gi\|2293... EFTS_GEOKA - Elongation factor Ts OS=Geobacillus kaustophilus GN=tsf PE=3 SV=1 EFTS_GEOKA - Elongation factor Ts OS=Geobacillus kaustophilus (strain HTA426) GN=tsf PE=3 SV=1 gi\|221088055, gi... - gi\|221088055\|ref\|ZP_03557589.1\| translation elongation factor Ts [Geobacillus sp. Y412MC61], gi\|2207...	382.0	[0..3]	[293..2]
EFTS_STAAB - Elongation factor Ts OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) GN=tsf PE=3 SV=1	378.0	[0..1]	[293..1]
gi\|221313852 - gi\|221313852\|ref\|ZP_03595657.1\| elongation factor Ts [Bacillus subtilis subsp. subtilis str. NCIB 36... EFTS_BACSU - Elongation factor Ts OS=Bacillus subtilis GN=tsf PE=1 SV=3 gi\|221318775 - gi\|221318775\|ref\|ZP_03600069.1\| elongation factor Ts [Bacillus subtilis subsp. subtilis str. JH642] EFTS_BACSU - Elongation factor Ts OS=Bacillus subtilis (strain 168) GN=tsf PE=1 SV=3 gi\|221323047 - gi\|221323047\|ref\|ZP_03604341.1\| elongation factor Ts [Bacillus subtilis subsp. subtilis str. SMY]	376.0	[0..3]	[293..2]

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Predicted Domain #1

Region A:
Residues: [1-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATISAKLVK ELREKTGAGM MDCKKALTET DGDIDKAIDY LREKGIAKAA KKADRIAAEG  60
   61 LVHVETKGND AVIVEINSET DFVARNEGFQ ELVKEIANQV LDTKAETVEA LMETTLPNGK 120
  121 SVDERIKEAI STIGEKLSVR RFAIRTKTDN DAFGAYLHMG GRIGVLTVVE GSTDEEAARD 180
  181 VAMHIAAINP KYVSSEQVSE EEINHEREVL KQQALNEGKP ENIVEKMVEG RLRKYLQEIC 240
  241 AVDQDFVKNP DVTVEAFLKT KGGKLVDFVR YEVGEGMEKR EENFADEVKG QMK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.522879
Match:	1efuB
Description:	Elongation factor Ts (EF-Ts), N-terminal domain; Elongation factor Ts (EF-Ts), dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation elongation factor activity	7.45583793023677	bayes_pls_golite062009
translation regulator activity	3.96278094372195	bayes_pls_golite062009
translation factor activity, nucleic acid binding	3.9473033844258	bayes_pls_golite062009
nucleic acid binding	3.82932150818666	bayes_pls_golite062009
binding	3.42735689097363	bayes_pls_golite062009
transcription regulator activity	1.03112855383055	bayes_pls_golite062009
DNA binding	0.853492612495239	bayes_pls_golite062009
ubiquitin binding	0.83381750627184	bayes_pls_golite062009
small conjugating protein binding	0.643709242447801	bayes_pls_golite062009
protein binding	0.259532204752794	bayes_pls_golite062009
catalytic activity	0.25774924710417	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: