YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264189, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	397 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264189, gi|....

Description	E-value	Query Range	Subject Range
RIBAB_AQUAE, RIB... - Riboflavin biosynthesis protein ribBA OS=Aquifex aeolicus GN=ribBA PE=3 SV=1, Riboflavin biosynthesi... RIBBA_AQUAE - Riboflavin biosynthesis protein RibBA OS=Aquifex aeolicus (strain VF5) GN=ribBA PE=3 SV=1	0.0	[2..395]	[9..406]
gi\|228648597, gi... - gi\|229134922\|ref\|ZP_04263729.1\| GTP cyclohydrolase-2 [Bacillus cereus BDRD-ST196], gi\|228648597\|gb\|E... RIBBA_BACWK - Riboflavin biosynthesis protein RibBA OS=Bacillus weihenstephanensis (strain KBAB4) GN=ribBA PE=3 SV...	0.0	[1..397]	[1..397]
gi\|228653998, gi... - gi\|229129393\|ref\|ZP_04258364.1\| GTP cyclohydrolase-2 [Bacillus cereus BDRD-Cer4], gi\|228653998\|gb\|EE... RIBBA_BACCR - Riboflavin biosynthesis protein RibBA OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NB...	0.0	[1..397]	[1..397]
gi\|28202834, gi\|... - gi\|28210397\|ref\|NP_781341.1\| riboflavin biosynthesis protein ribA [Clostridium tetani E88], gi\|28202...	0.0	[2..396]	[7..401]
gi\|47568172, gi\|... - gi\|47568172\|ref\|ZP_00238876.1\| 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II [...	0.0	[1..397]	[1..397]
RIBBA_BACCZ - Riboflavin biosynthesis protein RibBA OS=Bacillus cereus (strain ZK / E33L) GN=ribBA PE=3 SV=1	0.0	[1..397]	[1..397]
gi\|220931844, gi... - gi\|89210620\|ref\|ZP_01189007.1\| 3,4-Dihydroxy-2-butanone 4-phosphate synthase:GTP cyclohydrolase II [...	0.0	[3..397]	[2..396]
RIBBA_BACC1 - Riboflavin biosynthesis protein RibBA OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=ribBA PE=3...	0.0	[1..397]	[1..397]
gi\|89894410, gi\|... - gi\|89894410\|ref\|YP_517897.1\| GTP cyclohydrolase II [Desulfitobacterium hafniense Y51], gi\|89333858\|d...	0.0	[2..396]	[8..402]
gi\|53735199, gi\|... - gi\|67922265\|ref\|ZP_00515778.1\| 3,4-Dihydroxy-2-butanone 4-phosphate synthase:GTP cyclohydrolase II [...	0.0	[2..395]	[11..409]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFHRIEEALE DLKQGKVVIV CDDENRENEG DFIALAEYIT PETINFMITH GRGLVCVPIT  60
   61 EGYAERLQLE PMVSHNTDSH HTAFTVSIDH VSTTTGISAH ERATTIQQLL NPASKGADFN 120
  121 RPGHIFPLIA KEGGVLRRAG HTEAAVDLAQ LCGAEPAGVI CEIINEDGTM ARVPDLLQCA 180
  181 KQFDIKMITI EDLIAYRRHH E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.69897
Match:	1iezA
Description:	3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase, RibB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3,4-dihydroxy-2-butanone-4-phosphate synthase activity	7.56167968780416	bayes_pls_golite062009
GTP cyclohydrolase activity	2.51581618679202	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1.92717548101547	bayes_pls_golite062009
cyclohydrolase activity	1.48770406828775	bayes_pls_golite062009
binding	1.05088380360844	bayes_pls_golite062009
nucleic acid binding	0.637633326908211	bayes_pls_golite062009
catalytic activity	0.343636936190038	bayes_pls_golite062009
protein binding	0.291469273637145	bayes_pls_golite062009
DNA binding	0.21448652890147	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [202-397]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLVTREVEIT LPTDFGTFQA IGYSNSLDTK EHIALVKGDI STGEPVLVRV HSECLTGDVF  60
   61 GSCRCDCGPQ LHAALAQIER EGKGVLLYMR QEGRGIGLLN KLRAYKLQEE GFDTVEANEK 120
  121 LGFPADLRDY GIGAQILKDL GLQHLRLLTN NPRKIAGLQG YDLTVTERVP LQMPAKEENK 180
  181 TYLQTKVNKL GHLLNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.154902
Match:	2bz0A
Description:	Crystal Structure of E. coli GTP cyclohydrolase II in complex with GTP analogue, GMPcPP, and Zinc
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
GTP cyclohydrolase activity	4.36867535385235	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	3.7708397651039	bayes_pls_golite062009
cyclohydrolase activity	3.33696578638249	bayes_pls_golite062009
catalytic activity	1.40764037338379	bayes_pls_golite062009
binding	1.32693434551075	bayes_pls_golite062009
protein binding	0.418779722842637	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: