YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30256881, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	318 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30256881, gi|....

Description	E-value	Query Range	Subject Range
gi\|163862227, gi... - gi\|89209146\|ref\|ZP_01187602.1\| Thymidylate synthase [Bacillus weihenstephanensis KBAB4], gi\|89152920...	0.0	[1..318]	[1..318]
gi\|228807044, gi... - gi\|228952578\|ref\|ZP_04114654.1\| Thymidylate synthase [Bacillus thuringiensis serovar kurstaki str. T... gi\|206972712, gi... - gi\|206972712\|ref\|ZP_03233650.1\| thymidylate synthase [Bacillus cereus AH1134], gi\|206732367\|gb\|EDZ49... gi\|229091229, gi... - gi\|229091229\|ref\|ZP_04222449.1\| Thymidylate synthase [Bacillus cereus Rock3-42], gi\|228692127\|gb\|EEL... TYSY_BACCR - Thymidylate synthase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB ... gi\|218159915, gi... - gi\|218231958\|ref\|YP_002366936.1\| thymidylate synthase [Bacillus cereus B4264], gi\|218159915\|gb\|ACK59... gi\|229069766, gi... - gi\|229069766\|ref\|ZP_04203051.1\| Thymidylate synthase [Bacillus cereus F65185], gi\|228713387\|gb\|EEL65... gi\|228725361, gi... - gi\|229043979\|ref\|ZP_04191671.1\| Thymidylate synthase [Bacillus cereus AH676], gi\|228725361\|gb\|EEL766... gi\|228958506, gi... - gi\|228958506\|ref\|ZP_04120226.1\| Thymidylate synthase [Bacillus thuringiensis serovar pakistani str. ... gi\|228604763, gi... - gi\|229178605\|ref\|ZP_04305969.1\| Thymidylate synthase [Bacillus cereus 172560W], gi\|228604763\|gb\|EEK6... gi\|228638553, gi... - gi\|229144831\|ref\|ZP_04273228.1\| Thymidylate synthase [Bacillus cereus BDRD-ST24], gi\|228638553\|gb\|EE... gi\|228655712, gi... - gi\|229127635\|ref\|ZP_04256624.1\| Thymidylate synthase [Bacillus cereus BDRD-Cer4], gi\|228655712\|gb\|EE... gi\|228673720, gi... - gi\|229109679\|ref\|ZP_04239265.1\| Thymidylate synthase [Bacillus cereus Rock1-15], gi\|228673720\|gb\|EEL...	0.0	[1..318]	[1..318]
gi\|206743541, gi... - gi\|206978240\|ref\|ZP_03239119.1\| thymidylate synthase [Bacillus cereus H3081.97], gi\|206743541\|gb\|EDZ... gi\|217064386, gi... - gi\|217959749\|ref\|YP_002338301.1\| thymidylate synthase [Bacillus cereus AH187], gi\|217064386\|gb\|ACJ78... gi\|228939370, gi... - gi\|228939370\|ref\|ZP_04101961.1\| Thymidylate synthase [Bacillus thuringiensis serovar berliner ATCC 1... gi\|228972248, gi... - gi\|228972248\|ref\|ZP_04132862.1\| Thymidylate synthase [Bacillus thuringiensis serovar thuringiensis s... gi\|228851727, gi... - gi\|228907968\|ref\|ZP_04071819.1\| Thymidylate synthase [Bacillus thuringiensis IBL 200], gi\|228851727\|... TYSY_BACC1 - Thymidylate synthase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=thyA PE=3 SV=1 gi\|228780885, gi... - gi\|228978863\|ref\|ZP_04139231.1\| Thymidylate synthase [Bacillus thuringiensis Bt407], gi\|228780885\|gb...	0.0	[1..318]	[1..318]
TYSY_BACCN - Thymidylate synthase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) G...	0.0	[1..318]	[1..318]
TYSY_BACCZ - Thymidylate synthase OS=Bacillus cereus (strain ZK / E33L) GN=thyA PE=3 SV=1	0.0	[1..318]	[1..318]
gi\|228858754, gi... - gi\|228900828\|ref\|ZP_04065043.1\| Thymidylate synthase [Bacillus thuringiensis IBL 4222], gi\|228858754... gi\|75764380, gi\|... - gi\|75764380\|ref\|ZP_00743896.1\| Thymidylate synthase [Bacillus thuringiensis serovar israelensis ATCC...	0.0	[1..318]	[1..318]
gi\|47570165, gi\|... - gi\|47570165\|ref\|ZP_00240821.1\| thymidylate synthase [Bacillus cereus G9241], gi\|47553184\|gb\|EAL11579...	0.0	[1..318]	[1..318]
TYSY_ENTFA - Thymidylate synthase OS=Enterococcus faecalis (strain ATCC 700802 / V583) GN=thyA PE=1 SV=1 gi\|229550000, gi... - gi\|229550000\|ref\|ZP_04438725.1\| thymidylate synthase [Enterococcus faecalis ATCC 29200], gi\|22930491... gi\|227073762, gi... - gi\|227518767\|ref\|ZP_03948816.1\| thymidylate synthase [Enterococcus faecalis TX0104], gi\|227073762\|gb... TYSY_ENTFA - Thymidylate synthase OS=Enterococcus faecalis GN=thyA PE=3 SV=1 gi\|227553378, gi... - gi\|227553378\|ref\|ZP_03983427.1\| thymidylate synthase [Enterococcus faecalis HH22], gi\|227177483\|gb\|E...	0.0	[5..318]	[2..315]
gi\|227070060, gi... - gi\|227364913\|ref\|ZP_03848958.1\| thymidylate synthase [Lactobacillus reuteri MM2-3], gi\|227070060\|gb\|... TYSY_LACRD - Thymidylate synthase OS=Lactobacillus reuteri (strain DSM 20016) GN=thyA PE=3 SV=1 gi\|227531102, gi... - gi\|227531102\|ref\|ZP_03961151.1\| thymidylate synthase [Lactobacillus reuteri MM4-1A], gi\|227194312\|gb... gi\|148544000, gi... - gi\|89091235\|ref\|ZP_01164253.1\| Thymidylate synthase [Lactobacillus reuteri JCM 1112], gi\|89078948\|gb...	0.0	[5..318]	[7..320]
gi\|91803321, gi\|... - gi\|92089914\|ref\|ZP_01274835.1\| Thymidylate synthase [Lactobacillus reuteri 100-23], gi\|91803321\|gb\|E...	0.0	[5..318]	[7..320]

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Predicted Domain #1

Region A:
Residues: [1-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHAENEYLN LCRHVMEHGT KKEDRTGTGT VSVFGYQMRF DLSKGFPLLT TKRVPFRLVA  60
   61 SELLWFMKGD TNIRYLLQHN NNIWNEWAFK SWVESDEYTG PDMIDFGLRS QQDEEFKVQY 120
  121 DEQMELFKKN VLEDDEFSNK YGYLGDVYGK QWRAWKTTAG ETLDQLKDVI EMIKKTPDSR 180
  181 RLIVSAWNPE DVPSMALPPC HTLFQFYVAD GKLSCQLYQR SGDIFLGIPF NIASYSLLTH 240
  241 LIAHECGLEV GEFVHTIGDA HIYTNHFEQV EKQLAREPRP FPKLTLNPDV KSVFDFEMED 300
  301 LTIEGYDPHP AIKAPVAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	134.0
Match:	1lcaA
Description:	LACTOBACILLUS CASEI THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH DUMP AND CB3717
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thymidylate synthase activity	6.6988475347328	bayes_pls_golite062009
5,10-methylenetetrahydrofolate-dependent methyltransferase activity	6.29181090719132	bayes_pls_golite062009
binding	1.89072001556053	bayes_pls_golite062009
catalytic activity	1.73427871128495	bayes_pls_golite062009
transferase activity	1.72626940963556	bayes_pls_golite062009
methyltransferase activity	0.927096828883487	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.91282507161672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: