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View Structure Prediction Details

Protein: gi|30265292, gi|...
Organism: Bacillus anthracis str. Ames
Length: 549 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30265292, gi|....

Description E-value Query
Range
Subject
Range
ABCB4 - ATP-binding cassette, sub-family B (MDR/TAP), member 4
1.0E-77 [2..549] [374..914]
gi|114614720 - gi|114614720|ref|XP_001160982.1| PREDICTED: ATP-binding cassette, subfamily B, member 4 [Pan troglod...
2.0E-77 [2..549] [686..1226]
gi|46394986 - gi|46394986|gb|AAS91649.1| multidrug resistance protein 1a; P-glycoprotein [Rattus norvegicus]
1.0E-76 [1..549] [361..907]
MDR3_CRIGR - Phosphatidylcholine translocator ABCB4 OS=Cricetulus griseus GN=ABCB4 PE=2 SV=1
1.0E-76 [2..549] [374..916]
gi|60326712 - gi|60326712|gb|AAX18881.1| P-glycoprotein [Cercopithecus aethiops]
1.0E-76 [3..549] [373..915]
gi|31442763 - gi|31442763|gb|AAN07780.2| multidrug resistance p-glycoprotein [Macaca fascicularis]
2.0E-76 [3..549] [376..918]

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Predicted Domain #1
Region A:
Residues: [1-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYKVKFEHV TKKYKLYNKP FDKLKDLFFR SKDGEYHYAL NNISFEVPEG EIVGIVGLNG  60
   61 SGKSTLSNLI AGVTMPNKGT VDIKGSAALI AISSGLNGQL TGIENIELKG LMMGITKEKI 120
  121 KEIIPEIIDF ADIGKFMYQP VKTYSSGMKS RLGFAISVHI NPDILVIDEA LSVGDQTFTK 180
  181 KCLDKMNEFK EQGKTIFFIS HSLSQVKSFC TKALWLHYGQ VKEYGDIKEI VDHYDEFLKK 240
  241 YNQMSVEERK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.09691
Match: 2d62A
Description: No description for 2d62A was found.

Predicted Domain #2
Region A:
Residues: [251-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLRKEQISQF QHGLLQEDQT GRERKRKKGK KTSRKFKKKR VLITGVCIAL LTGIISTGYY  60
   61 YKNLLPFNSE NKYAEKVASK ENVTESKQMV KKEKGAAKYI VNS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.11
Match: 1griA
Description: Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ion transmembrane transporter activity 2.65908270074388 bayes_pls_golite062009
hydrolase activity 2.62407085847428 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.49725308559723 bayes_pls_golite062009
protein binding 2.4610205810239 bayes_pls_golite062009
binding 1.92514783797107 bayes_pls_golite062009
transporter activity 1.31240426494436 bayes_pls_golite062009
transmembrane transporter activity 1.09313194256023 bayes_pls_golite062009
signal transducer activity 0.939311498702736 bayes_pls_golite062009
molecular transducer activity 0.939311498702736 bayes_pls_golite062009
substrate-specific transporter activity 0.827625988755198 bayes_pls_golite062009
receptor binding 0.284818625085595 bayes_pls_golite062009
protein phosphorylated amino acid binding 0.155969011554977 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [354-549]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGISIREEAD ASSKRLAIAN FGDIFTISDS NKNEKKDVEW IQITLSNGEI GWISTKFIEP  60
   61 FKSNNNIIED AKLADVTALL KRVYGGNMVS APTYFGKTLN ELETTYPQPL NPLPSMTGKT 120
  121 IVKDGNIQFG ISQDKVVEVV FQDISMSIAK LHELLGKESL SNDAEKNYFY ETKSYYIAAR 180
  181 SDQTHKEIQS ISIVKK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 2hbwA
Description: No description for 2hbwA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle