YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30264532, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30264532, gi|....

Description	E-value	Query Range	Subject Range
HEM3_VIBVY - Porphobilinogen deaminase OS=Vibrio vulnificus (strain YJ016) GN=hemC PE=3 SV=1 HEM3_VIBVU - Porphobilinogen deaminase OS=Vibrio vulnificus GN=hemC PE=3 SV=1 HEM3_VIBVU - Porphobilinogen deaminase OS=Vibrio vulnificus (strain CMCP6) GN=hemC PE=3 SV=1	0.0	[3..309]	[6..312]
gi\|90324688, gi\|... - gi\|90414241\|ref\|ZP_01222221.1\| porphobilinogen deaminase [Photobacterium profundum 3TCK], gi\|9032468...	0.0	[2..305]	[35..338]
gi\|32033974 - gi\|32033974\|ref\|ZP_00134230.1\| COG0181: Porphobilinogen deaminase [Actinobacillus pleuropneumoniae s...	0.0	[1..308]	[6..314]
gi\|24115097, gi\|... - ref\|NP_709607.1\| porphobilinogen deaminase = hydroxymethylbilane synthase [Shigella flexneri 2a str.... gi\|110617055, gi... - gi\|110807507\|ref\|YP_691027.1\| porphobilinogen deaminase [Shigella flexneri 5 str. 8401], gi\|11061705...	0.0	[4..308]	[13..317]
gi\|86148167, gi\|... - gi\|86148167\|ref\|ZP_01066465.1\| porphobilinogen deaminase [Vibrio sp. MED222], gi\|85834014\|gb\|EAQ5217... HEM3_VIBTL - Porphobilinogen deaminase OS=Vibrio tasmaniensis (strain LGP32) GN=hemC PE=3 SV=1	0.0	[3..309]	[6..312]
gi\|194438640, gi... - gi\|83585946\|ref\|ZP_00924585.1\| COG0181: Porphobilinogen deaminase [Escherichia coli 101-1], gi\|19443...	0.0	[4..307]	[11..314]
HEM3_SHIFL - Porphobilinogen deaminase OS=Shigella flexneri GN=hemC PE=3 SV=2 gi\|30043162, gi\|... - gi\|30064902\|ref\|NP_839073.1\| porphobilinogen deaminase [Shigella flexneri 2a str. 2457T], gi\|3004316... gi\|56383990, gi\|... - gi\|56480439\|ref\|NP_709607.2\| porphobilinogen deaminase [Shigella flexneri 2a str. 301], gi\|56383990\|...	0.0	[4..308]	[6..310]
gi\|75512636 - gi\|75512636\|ref\|ZP_00735148.1\| COG0181: Porphobilinogen deaminase [Escherichia coli 53638]	0.0	[4..307]	[11..314]
gi\|15833989, gi\|... - gi\|15833989\|ref\|NP_312762.1\| porphobilinogen deaminase [Escherichia coli O157:H7], gi\|13364211\|dbj\|B... gi\|209753312, gi... - gi\|25292187\|pir\|\|A86067 porphobilinogen deaminase [imported] - Escherichia coli (strain O157:H7, su... gi\|15804393, gi\|... - gi\|15804393\|ref\|NP_290433.1\| porphobilinogen deaminase [Escherichia coli O157:H7 EDL933], gi\|1251866... gi\|15833989, gi\|... - gi\|15833989\|ref\|NP_312762.1\| porphobilinogen deaminase [Escherichia coli O157:H7 str. Sakai], gi\|133...	0.0	[4..307]	[13..316]
gi\|194434066, gi... - gi\|83569364\|ref\|ZP_00920819.1\| COG0181: Porphobilinogen deaminase [Shigella dysenteriae 1012], gi\|19...	0.0	[4..307]	[11..314]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKIIVGSRK SKLALTQTNW FIDQLKALGL PYEFEVKEIV TKGDVILDVT LSKVGGKGLF  60
   61 VKEIEHALLT KEIDMAVHSM KDMPAVLPEG LMIGCTPKRV DPRDAFISKS GASYKELAEG 120
  121 AILGTSSLRR SAQLLAARPD LQVKWIRGNI DTRLRKLKEE DYDAIILATA GLQRMGWDNE 180
  181 VITEHLDETL CVPAVGQGAL AIECREDDKD LLQLLAHIND AVTEKTVAAE RVFLHKLEGG 240
  241 CQVPIAGYAT ITENDAIELT ALVGSMDGSV LLKETVVGTD PEKVGLEAAD RLIKQGAKEL 300
  301 ILAANKGQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	128.0
Match:	1ah5A
Description:	REDUCED FORM SELENOMETHIONINE-LABELLED HYDROXYMETHYLBILANE SYNTHASE DETERMINED BY MAD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	3.22743737647397	bayes_pls_golite062009
DNA binding	2.86883926687971	bayes_pls_golite062009
transcription factor activity	2.7948293378347	bayes_pls_golite062009
nucleic acid binding	2.66637887681284	bayes_pls_golite062009
binding	2.63182502368928	bayes_pls_golite062009
hydroxymethylbilane synthase activity	2.03196514141563	bayes_pls_golite062009
catalytic activity	0.674312982669564	bayes_pls_golite062009
transcription activator activity	0.050905489018976	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: