YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263769, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	453 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263769, gi|....

Description	E-value	Query Range	Subject Range
gi\|47555094, gi\|... - gi\|47568266\|ref\|ZP_00238969.1\| sensor histidine kinase, putative [Bacillus cereus G9241], gi\|4755509...	1.0E-67	[1..453]	[1..453]
gi\|21401745, gi\|... - gi\|65321090\|ref\|ZP_00394049.1\| COG0642: Signal transduction histidine kinase [Bacillus anthracis str...	8.0E-67	[1..453]	[1..453]
gi\|28210359, gi\|... - gi\|28210359\|ref\|NP_781303.1\| subtilin biosynthesis sensor protein spaK [Clostridium tetani E88], gi\|...	1.0E-65	[1..452]	[1..452]
gi\|45358866, gi\|... - gi\|45358866\|ref\|NP_988423.1\| sensory transduction histidine kinase [Methanococcus maripaludis S2], g...	4.0E-65	[113..452]	[282..633]
gi\|20808918 - gi\|20808918\|ref\|NP_624089.1\| Sensory transduction histidine kinase [Thermoanaerobacter tengcongensis... gi\|20808918, gi\|... - gi\|20808918\|ref\|NP_624089.1\| sensory transduction histidine kinase [Thermoanaerobacter tengcongensis...	6.0E-65	[4..452]	[1..465]
gi\|82723689, gi\|... - gi\|82748422\|ref\|ZP_00910906.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	1.0E-64	[1..452]	[1..454]
gi\|68186676, gi\|... - gi\|91772668\|ref\|YP_565360.1\| PAS/PAC sensor signal transduction histidine kinase [Methanococcoides b...	8.0E-63	[57..452]	[47..448]
gi\|91203275 - gi\|91203275\|emb\|CAJ72914.1\| conserved hypothetical protein [Candidatus Kuenenia stuttgartiensis]	8.0E-63	[157..452]	[208..526]
gi\|166853488, gi... - gi\|167039248\|ref\|YP_001662233.1\| integral membrane sensor signal transduction histidine kinase [Ther... gi\|241904558, gi... - gi\|241904558\|ref\|ZP_04789245.1\| histidine kinase [Thermoanaerobacter brockii subsp. finnii Ako-1], g... gi\|76588655, gi\|... - gi\|76795887\|ref\|ZP_00778257.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	1.0E-62	[4..451]	[1..465]
gi\|229129951, gi... - gi\|229129951\|ref\|ZP_04258917.1\| hypothetical protein bcere0015_43910 [Bacillus cereus BDRD-Cer4], gi... gi\|30022741, gi\|... - gi\|30022741\|ref\|NP_834372.1\| two component system histidine kinase [Bacillus cereus ATCC 14579], gi\|...	7.0E-62	[2..451]	[1..476]

Back

Predicted Domain #1

Region A:
Residues: [1-133]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKVKKQVNL SKILIQYIFA FSIGTIALVT FFMILFQVGV NAEIILPANY YEKQIESQRD  60
   61 AIVKAEQEDD QILKQYKYAL YDFSGNVIQG SINKDYAGQI WNNIHNDEKG DSKYYYAIIE 120
  121 RDKDICVILY TLH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [134-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATFKNPILQK YVPSPEVCEI VLFILLFVAE VIFLSRSFGK SLSKEMMILR KVTDKIQKED  60
   61 LDFQVEQSKI KEVNEVLTSL VKMKDELNHS LR

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.34
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [226-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQWNMETNRR EQIAALAHDI KTPLTILRGN AELLNESMLD SNQKKCNEHI LKSIDEMEIY  60
   61 MKSLLDITKC EEGAPLQFMQ TDLRDFIHNI IEESAICVLG KQLNLIENVQ DIPNFIPIDE 120
  121 TALKRAIMNI MMNAIEYSPT KGDLMFSVEM ISEKLQFIVE DSGRGFTEEE MHSATEQFYR 180
  181 GDKSRNAKDH HGMGLYIAKS FAKQHGGNLY LSNSEKLHGA KVVLEISA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits