YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263769, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	453 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263769, gi|....

Description	E-value	Query Range	Subject Range
gi\|47555094, gi\|... - gi\|47568266\|ref\|ZP_00238969.1\| sensor histidine kinase, putative [Bacillus cereus G9241], gi\|4755509...	1.0E-67	[1..453]	[1..453]
gi\|21401745, gi\|... - gi\|65321090\|ref\|ZP_00394049.1\| COG0642: Signal transduction histidine kinase [Bacillus anthracis str...	8.0E-67	[1..453]	[1..453]
gi\|28210359, gi\|... - gi\|28210359\|ref\|NP_781303.1\| subtilin biosynthesis sensor protein spaK [Clostridium tetani E88], gi\|...	1.0E-65	[1..452]	[1..452]
gi\|45358866, gi\|... - gi\|45358866\|ref\|NP_988423.1\| sensory transduction histidine kinase [Methanococcus maripaludis S2], g...	4.0E-65	[113..452]	[282..633]
gi\|20808918 - gi\|20808918\|ref\|NP_624089.1\| Sensory transduction histidine kinase [Thermoanaerobacter tengcongensis... gi\|20808918, gi\|... - gi\|20808918\|ref\|NP_624089.1\| sensory transduction histidine kinase [Thermoanaerobacter tengcongensis...	6.0E-65	[4..452]	[1..465]
gi\|82723689, gi\|... - gi\|82748422\|ref\|ZP_00910906.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	1.0E-64	[1..452]	[1..454]
gi\|68186676, gi\|... - gi\|91772668\|ref\|YP_565360.1\| PAS/PAC sensor signal transduction histidine kinase [Methanococcoides b...	8.0E-63	[57..452]	[47..448]
gi\|91203275 - gi\|91203275\|emb\|CAJ72914.1\| conserved hypothetical protein [Candidatus Kuenenia stuttgartiensis]	8.0E-63	[157..452]	[208..526]
gi\|166853488, gi... - gi\|167039248\|ref\|YP_001662233.1\| integral membrane sensor signal transduction histidine kinase [Ther... gi\|241904558, gi... - gi\|241904558\|ref\|ZP_04789245.1\| histidine kinase [Thermoanaerobacter brockii subsp. finnii Ako-1], g... gi\|76588655, gi\|... - gi\|76795887\|ref\|ZP_00778257.1\| ATP-binding region, ATPase-like:Histidine kinase, HAMP region:Histidi...	1.0E-62	[4..451]	[1..465]
gi\|229129951, gi... - gi\|229129951\|ref\|ZP_04258917.1\| hypothetical protein bcere0015_43910 [Bacillus cereus BDRD-Cer4], gi... gi\|30022741, gi\|... - gi\|30022741\|ref\|NP_834372.1\| two component system histidine kinase [Bacillus cereus ATCC 14579], gi\|...	7.0E-62	[2..451]	[1..476]

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Predicted Domain #1

Region A:
Residues: [1-133]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKVKKQVNL SKILIQYIFA FSIGTIALVT FFMILFQVGV NAEIILPANY YEKQIESQRD  60
   61 AIVKAEQEDD QILKQYKYAL YDFSGNVIQG SINKDYAGQI WNNIHNDEKG DSKYYYAIIE 120
  121 RDKDICVILY TLH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [134-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATFKNPILQK YVPSPEVCEI VLFILLFVAE VIFLSRSFGK SLSKEMMILR KVTDKIQKED  60
   61 LDFQVEQSKI KEVNEVLTSL VKMKDELNHS LR

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.34
Match:	2f95B
Description:	M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [226-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQWNMETNRR EQIAALAHDI KTPLTILRGN AELLNESMLD SNQKKCNEHI LKSIDEMEIY  60
   61 MKSLLDITKC EEGAPLQFMQ TDLRDFIHNI IEESAICVLG KQLNLIENVQ DIPNFIPIDE 120
  121 TALKRAIMNI MMNAIEYSPT KGDLMFSVEM ISEKLQFIVE DSGRGFTEEE MHSATEQFYR 180
  181 GDKSRNAKDH HGMGLYIAKS FAKQHGGNLY LSNSEKLHGA KVVLEISA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits