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View Structure Prediction Details

Protein: gi|30263761, gi|...
Organism: Bacillus anthracis str. Ames
Length: 329 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263761, gi|....

Description E-value Query
Range
Subject
Range
PLC_BACCE - 1-phosphatidylinositol phosphodiesterase OS=Bacillus cereus PE=1 SV=1
3.0E-87 [1..329] [1..329]
gi|229047444, gi... - gi|229047444|ref|ZP_04193036.1| 1-phosphatidylinositol phosphodiesterase [Bacillus cereus AH676], gi...
gi|29897410, gi|... - gi|30021854|ref|NP_833485.1| 1-phosphatidylinositol phosphodiesterase precursor [Bacillus cereus ATC...
gi|228636966, gi... - gi|229146333|ref|ZP_04274704.1| 1-phosphatidylinositol phosphodiesterase [Bacillus cereus BDRD-ST24]...
gi|229129038, gi... - gi|229129038|ref|ZP_04258011.1| 1-phosphatidylinositol phosphodiesterase [Bacillus cereus BDRD-Cer4]...
1.0E-85 [1..329] [1..329]
PLC_BACTU - 1-phosphatidylinositol phosphodiesterase OS=Bacillus thuringiensis PE=1 SV=1
gi|228973759, gi... - gi|228973759|ref|ZP_04134337.1| 1-phosphatidylinositol phosphodiesterase [Bacillus thuringiensis ser...
gi|228940839, gi... - gi|228940839|ref|ZP_04103399.1| 1-phosphatidylinositol phosphodiesterase [Bacillus thuringiensis ser...
gi|228980315, gi... - gi|228980315|ref|ZP_04140626.1| 1-phosphatidylinositol phosphodiesterase [Bacillus thuringiensis Bt4...
1.0E-85 [1..329] [1..329]
gi|42782843, gi|... - gi|42782843|ref|NP_980090.1| 1-phosphatidylinositol phosphodiesterase [Bacillus cereus ATCC 10987], ...
2.0E-85 [1..329] [1..329]
gi|52141734, gi|... - gi|52141734|ref|YP_085095.1| glycosylphosphatidylinositol diacylglycerol-lyase [Bacillus cereus E33L...
7.0E-85 [1..329] [1..329]
gi|49479426, gi|... - gi|49479426|ref|YP_037821.1| glycosylphosphatidylinositol diacylglycerol-lyase [Bacillus thuringiens...
1.0E-84 [1..329] [1..329]
gi|218898862, gi... - gi|218898862|ref|YP_002447273.1| phosphatidylinositol diacylglycerol-lyase [Bacillus cereus G9842], ...
gi|228792988, gi... - gi|228966688|ref|ZP_04127733.1| 1-phosphatidylinositol phosphodiesterase [Bacillus thuringiensis ser...
gi|228902265, gi... - gi|228902265|ref|ZP_04066425.1| 1-phosphatidylinositol phosphodiesterase [Bacillus thuringiensis IBL...
gi|75760278, gi|... - gi|75760278|ref|ZP_00740329.1| 1-phosphatidylinositol phosphodiesterase precursor [Bacillus thuringi...
1.0E-83 [1..326] [1..326]

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Predicted Domain #1
Region A:
Residues: [1-329]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKKFILKL FICSTIFITF VFALHDKRVV AASSVNELEN WSRWMQPIPD NIPLARISIP  60
   61 GTHDSGTFKL QNPIKQVWGM TQEHDFRYQM EHGARIFDIR GRLTDDNTIV LHHGPLYLYV 120
  121 TLHEFINEAK QFLKDNPSET IIMSLKKEYE DMKGAEGSFS STFEKSYFVD PIFLKTEGNI 180
  181 KLGDARGKIV LLKRYSGSNE SGGYNNFYWP DNETFTTTVN QNVNVTVQDK YKVSYDEKVK 240
  241 SIKDTINETM NNSEDLHHLY INFASLSSGG TAWNSPYYYA SYINPEIANY IKQKSPTRVG 300
  301 WIIQDYINEK WSPLLYQEVI RANKSLIRD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.0
Match: 7ptdA
Description: PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT R163K
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glycerophosphodiester phosphodiesterase activity 4.27697417361287 bayes_pls_golite062009
phosphoric diester hydrolase activity 3.96663444882989 bayes_pls_golite062009
phospholipase C activity 3.23617371612061 bayes_pls_golite062009
phospholipase activity 3.13446628847723 bayes_pls_golite062009
phosphoric ester hydrolase activity 2.78581224243111 bayes_pls_golite062009
inositol or phosphatidylinositol phosphodiesterase activity 2.723593331359 bayes_pls_golite062009
phosphoinositide phospholipase C activity 2.723593331359 bayes_pls_golite062009
hydrolase activity 1.6037255441021 bayes_pls_golite062009
catalytic activity 1.22328099675039 bayes_pls_golite062009
lipase activity 1.19845754386405 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.753651903859164 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle