YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49180409, gi\|...
Organism:	Bacillus anthracis str. Sterne
Length:	269 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49180409, gi|....

Description	E-value	Query Range	Subject Range
gi\|51975318, gi\|... - gi\|52141849\|ref\|YP_084980.1\| LexA repressor [Bacillus cereus E33L], gi\|51975318\|gb\|AAU16868.1\| LexA ...	1.0E-93	[1..269]	[1..269]
gi\|65320962 - gi\|65320962\|ref\|ZP_00393921.1\| COG1974: SOS-response transcriptional repressors (RecA-mediated autop... gi\|229092669, gi... - gi\|229092669\|ref\|ZP_04223817.1\| LexA repressor [Bacillus cereus Rock3-42], gi\|228690696\|gb\|EEL44473.... gi\|229157270, gi... - gi\|229157270\|ref\|ZP_04285350.1\| LexA repressor [Bacillus cereus ATCC 4342], gi\|228626334\|gb\|EEK83081... gi\|229140342, gi... - gi\|229140342\|ref\|ZP_04268897.1\| LexA repressor [Bacillus cereus BDRD-ST26], gi\|228642903\|gb\|EEK99179...	8.0E-62	[55..269]	[1..215]
LEXA_BACCR - LexA repressor - Bacillus cereus (strain ATCC 14579 / DSM 31)	2.0E-60	[60..269]	[1..210]
gi\|254733655 - gi\|254733655\|ref\|ZP_05191371.1\| LexA repressor [Bacillus anthracis str. Western North America USA615... gi\|47569215, gi\|... - gi\|47569215\|ref\|ZP_00239901.1\| LexA repressor [Bacillus cereus G9241], gi\|47554089\|gb\|EAL12454.1\| Le... LEXA_BACAH - LexA repressor OS=Bacillus thuringiensis (strain Al Hakam) GN=lexA PE=3 SV=1 LEXA_BACAN - LexA repressor OS=Bacillus anthracis GN=lexA PE=3 SV=1 gi\|170125798, gi... - gi\|170709289\|ref\|ZP_02899707.1\| LexA repressor [Bacillus anthracis str. A0389], gi\|170125798\|gb\|EDS9... LEXA_BACC1 - LexA repressor OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=lexA PE=3 SV=1 gi\|177655861, gi... - gi\|177655861\|ref\|ZP_02937076.1\| LexA repressor [Bacillus anthracis str. A0174], gi\|172079958\|gb\|EDT6... gi\|206735697, gi... - gi\|206968656\|ref\|ZP_03229611.1\| LexA repressor [Bacillus cereus AH1134], gi\|206735697\|gb\|EDZ52855.1\|... gi\|206743507, gi... - gi\|206978303\|ref\|ZP_03239180.1\| LexA repressor [Bacillus cereus H3081.97], gi\|206743507\|gb\|EDZ54937.... LEXA_BACC0 - LexA repressor OS=Bacillus cereus (strain AH820) GN=lexA PE=3 SV=1 LEXA_BACCZ - LexA repressor OS=Bacillus cereus (strain ZK / E33L) GN=lexA PE=3 SV=2 LEXA_BACCQ - LexA repressor OS=Bacillus cereus (strain Q1) GN=lexA PE=3 SV=1 LEXA_BACHK - LexA repressor OS=Bacillus thuringiensis subsp. konkukian GN=lexA PE=3 SV=1 LEXA_BACCR - LexA repressor OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 /... gi\|165873206, gi... - gi\|165873206\|ref\|ZP_02217818.1\| LexA repressor [Bacillus anthracis str. A0488], gi\|164711043\|gb\|EDR1... gi\|167510074, gi... - gi\|167641981\|ref\|ZP_02400215.1\| LexA repressor [Bacillus anthracis str. A0193], gi\|167510074\|gb\|EDR8... LEXA_BACHK - LexA repressor OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=lexA PE=3 SV=1 gi\|47504192, gi\|... - gi\|47529044\|ref\|YP_020393.1\| LexA repressor [Bacillus anthracis str. 'Ames Ancestor'], gi\|47504192\|g... gi\|30263637, gi\|... - gi\|30263637\|ref\|NP_846014.1\| LexA repressor [Bacillus anthracis str. Ames], gi\|30258272\|gb\|AAP27500.... gi\|21401610 - ref\|NP_657595.1\| Peptidase_S24, Peptidase family S24 [Bacillus anthracis str. A2012]	1.0E-59	[64..269]	[1..206]
LEXA_BACCN - LexA repressor OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) GN=lexA...	4.0E-59	[64..269]	[1..206]
LEXA_BACWK - LexA repressor OS=Bacillus weihenstephanensis (strain KBAB4) GN=lexA PE=3 SV=1	2.0E-58	[64..269]	[1..204]
LEXA_BACHD - LexA repressor OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-12... LEXA_BACHD - LexA repressor OS=Bacillus halodurans GN=lexA PE=3 SV=1	2.0E-56	[64..269]	[1..207]
gi\|221323190 - gi\|221323190\|ref\|ZP_03604484.1\| LexA repressor [Bacillus subtilis subsp. subtilis str. SMY] gi\|221318916 - gi\|221318916\|ref\|ZP_03600210.1\| LexA repressor [Bacillus subtilis subsp. subtilis str. JH642] gi\|221313994 - gi\|221313994\|ref\|ZP_03595799.1\| LexA repressor [Bacillus subtilis subsp. subtilis str. NCIB 3610] LEXA_BACSU - LexA repressor OS=Bacillus subtilis (strain 168) GN=lexA PE=1 SV=1 LEXA_BACSU - LexA repressor OS=Bacillus subtilis GN=lexA PE=1 SV=1	2.0E-56	[64..269]	[1..205]
LEXA_BACLD - LexA repressor OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB...	2.0E-55	[64..269]	[1..207]
LEXA_GEOKA - LexA repressor OS=Geobacillus kaustophilus (strain HTA426) GN=lexA PE=3 SV=1 LEXA_GEOKA - LexA repressor OS=Geobacillus kaustophilus GN=lexA PE=3 SV=1 gi\|220706617, gi... - gi\|221089449\|ref\|ZP_03558967.1\| transcriptional repressor, LexA family [Geobacillus sp. Y412MC61], g... gi\|229328639, gi... - gi\|229500460\|ref\|ZP_04394122.1\| SOS-response transcriptional repressor, LexA [Geobacillus sp. Y412MC...	2.0E-55	[64..266]	[1..204]

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Predicted Domain #1

Region A:
Residues: [1-269]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRFFRCTHTC INNCIHYEPL FLTIISLQCN INSPFVRTYV CRMFFHMLYL LIRKMKENEV  60
   61 LENMEKLTKR QQDILDFIKL KVQEKGYPPS VREIGQAVGL ASSSTVHGHL SRLEEKGYIR 120
  121 RDPTKPRAIE ILGEDRMDTE TQSVIQVPIV GKVTAGLPIT AVESVEEHFP LPASIVAGAD 180
  181 QVFMLRISGD SMIEAGIFDG DLVVVRQQQS AYNGEIVVAL TEDNEATVKR FYKEKDHFRL 240
  241 QPENSSLEPI ILKQVSVIGK VIGVYRDLH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.522879
Match:	1jhhA
Description:	LexA repressor, N-terminal DNA-binding domain; LexA C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.30784351115827	bayes_pls_golite062009
nucleic acid binding	0.603302373860066	bayes_pls_golite062009
DNA binding	0.452668330421957	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
binding	0.355412070907203	bayes_pls_golite062009
transcription factor activity	0.0554645717043947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: