YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30257979, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	335 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257979, gi|....

Description	E-value	Query Range	Subject Range
gi\|29897039, gi\|... - gi\|30021484\|ref\|NP_833115.1\| quinone oxidoreductase [Bacillus cereus ATCC 14579], gi\|29897039\|gb\|AAP... gi\|228654852, gi... - gi\|229128659\|ref\|ZP_04257637.1\| Oxidoreductase, zinc-binding dehydrogenase [Bacillus cereus BDRD-Cer...	2.0E-88	[1..335]	[1..331]
gi\|52142155, gi\|... - gi\|52142155\|ref\|YP_084674.1\| quinone oxidoreductase (NADPH:quinone reductase) [Bacillus cereus E33L]...	3.0E-88	[1..335]	[1..331]
gi\|49479262, gi\|... - gi\|49479262\|ref\|YP_037491.1\| quinone oxidoreductase (NADPH:quinone reductase) [Bacillus thuringiensi...	5.0E-88	[1..335]	[1..331]
gi\|47558675, gi\|... - gi\|47564523\|ref\|ZP_00235568.1\| alcohol dehydrogenase, zinc-containing [Bacillus cereus G9241], gi\|47...	2.0E-87	[1..335]	[1..331]
gi\|86134306, gi\|... - gi\|86134306\|ref\|ZP_01052888.1\| zinc-binding dehydrogenase [Polaribacter sp. MED152], gi\|85821169\|gb\|...	9.0E-85	[1..331]	[12..333]
gi\|28872343, gi\|... - gi\|28872343\|ref\|NP_794962.1\| oxidoreductase, zinc-binding [Pseudomonas syringae pv. tomato str. DC30... tr\|Q87UR5\|Q87UR5... - Oxidoreductase, zinc-binding protein OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_523...	5.0E-82	[1..333]	[1..324]
gi\|2983768, gi\|1... - gi\|2983768\|gb\|AAC07327.1\| alcohol dehydrogenase [Aquifex aeolicus VF5], gi\|15606558\|ref\|NP_213938.1\|... gi\|7427649 - pir\|\|C70418 probable alcohol dehydrogenase (EC 1.1.1.-) - Aquifex aeolicus	2.0E-80	[1..333]	[1..342]
gi\|71733591, gi\|... - gi\|71733591\|ref\|YP_272602.1\| quinone oxidoreductase [Pseudomonas syringae pv. phaseolicola 1448A], g...	3.0E-80	[1..333]	[1..324]
gi\|75812768, gi\|... - gi\|75812768\|ref\|YP_320385.1\| zinc-containing alcohol dehydrogenase superfamily protein [Anabaena var...	4.0E-80	[1..332]	[321..635]
gi\|77385669, gi\|... - gi\|77461666\|ref\|YP_351173.1\| zinc-containing alcohol dehydrogenase superfamily protein [Pseudomonas ...	9.0E-80	[1..333]	[1..324]

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Predicted Domain #1

Region A:
Residues: [1-335]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAQIIHSFG DSSVFQLEEV SKPKLLPGHV LIDVKATSVN PIDTKMRSGA VSAVAPEFPA  60
   61 ILHGDVAGIV IEVGEGVSKF KCGDEVYGCA GGFKETGGAL AEFMLADARL IAHKPNNITM 120
  121 EEAAALPLVA ITAWESLFDR ANIKSGQNVL IHGATGGVGH VAIQLAKWAG ANVFTTASQQ 180
  181 NKMEIAHRLG ADVAINYKEE SVQESVQEYV QKHTNGNGFE VIFDTVGGKN LDNSFEAAAV 240
  241 NGTVVTIAAR STHDLSPLHA KGLSLHVTFM ALKILHTDKR NDCGEILTKI TKIVEEGKLR 300
  301 PLLDSKSFTF DEVAQAHEYL ESNKAIGKIV LKNVW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.09691
Match:	1rjwA
Description:	CRYSTAL STRUCTURE OF NAD(+)-DEPENDENT ALCOHOL DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS STRAIN LLD-R
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.72453765142308	bayes_pls_golite062009
protein binding	2.40625250158019	bayes_pls_golite062009
oxidoreductase activity	2.38343643417648	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	2.12541893067778	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	1.9802813264034	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	1.44179293407232	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1.34145234546943	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	1.22416351603098	bayes_pls_golite062009
chaperone binding	1.04678886151518	bayes_pls_golite062009
retinol dehydrogenase activity	1.04497968922284	bayes_pls_golite062009
DNA binding	0.940078857029005	bayes_pls_golite062009
transcription regulator activity	0.854100257756792	bayes_pls_golite062009
RNA binding	0.843556706364142	bayes_pls_golite062009
transporter activity	0.793769336118517	bayes_pls_golite062009
nucleic acid binding	0.787328837435283	bayes_pls_golite062009
transmembrane transporter activity	0.635891484075352	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.576163737662951	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.51503848775098	bayes_pls_golite062009
L-iditol 2-dehydrogenase activity	0.472271922915951	bayes_pls_golite062009
coenzyme binding	0.46570602169425	bayes_pls_golite062009
NAD or NADH binding	0.46286018152257	bayes_pls_golite062009
transcription factor activity	0.35056694435192	bayes_pls_golite062009
substrate-specific transporter activity	0.300373102236296	bayes_pls_golite062009
active transmembrane transporter activity	0.239024094835991	bayes_pls_golite062009
catalytic activity	0.217171374336363	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.165260811069909	bayes_pls_golite062009
ion transmembrane transporter activity	0.0257250793986203	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: