YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263231, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	390 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263231, gi|....

Description	E-value	Query Range	Subject Range
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	9.0E-94	[1..386]	[1..391]
serA2 - serA2 putative phosphoglycerate dehydrogenase 4858096:4859685 reverse MW:56215 gi\|192293149, gi... - gi\|192293149\|ref\|YP_001993754.1\| D-3-phosphoglycerate dehydrogenase [Rhodopseudomonas palustris TIE-...	1.0E-89	[2..386]	[4..394]
gi\|78518910, gi\|... - gi\|78693355\|ref\|ZP_00857869.1\| D-3-phosphoglycerate dehydrogenase [Bradyrhizobium sp. BTAi1], gi\|785...	1.0E-89	[2..386]	[4..394]
gi\|22294046, gi\|... - gi\|22297868\|ref\|NP_681115.1\| D-3-phosphoglycerate dehydrogenase [Thermosynechococcus elongatus BP-1]...	2.0E-89	[1..386]	[1..392]
gi\|69274819, gi\|... - gi\|69274819\|ref\|ZP_00610731.1\| D-3-phosphoglycerate dehydrogenase [Mesorhizobium sp. BNC1], gi\|68193...	2.0E-89	[2..386]	[3..393]
gi\|26345686 - gi\|26345686\|dbj\|BAC36494.1\| unnamed protein product [Mus musculus]	2.0E-89	[3..386]	[8..397]
gi\|86748440, gi\|... - gi\|86748440\|ref\|YP_484936.1\| D-3-phosphoglycerate dehydrogenase [Rhodopseudomonas palustris HaA2], g...	3.0E-89	[2..386]	[4..394]
gi\|47564398, gi\|... - gi\|47564398\|ref\|ZP_00235443.1\| D-isomer specific 2-hydroxyacid dehydrogenase family protein [Bacillu...	3.0E-89	[1..390]	[1..390]
gi\|77652824, gi\|... - gi\|91978368\|ref\|YP_571027.1\| D-3-phosphoglycerate dehydrogenase [Rhodopseudomonas palustris BisB5], ...	6.0E-89	[2..386]	[4..394]

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Predicted Domain #1

Region A:
Residues: [1-390]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRVQTLNQI AEKGLQVLGG ERYEVGERIN HPDGILLRSY SLHQEEFSKD LKAIARAGAG  60
   61 VNNIPVERCT EKGIVVFNTP GANANAVKEL IIASLIMSSR NIINGVSWTK NLEGEEVPQL 120
  121 VESGKKQFVG SEIAGKRLGV IGLGAIGALV ANDALALGMD VVGYDPYISV ETAWRLSTHV 180
  181 QRAFSLDEIF ATCDYITLHI PLTNQTKGMI GEHAVEKMKK GMRLFNFSRG ELVDEKVLQK 240
  241 ALEEEIIAHY VTDFPNENVI KMKNVTATPH LGASTSESEE NCAVMAARQL REYLETGNIR 300
  301 NSVNYPNVEL PYIGKKRITI MHQNVPNMVG QITGCLAEHH INIADMINRS KHSWAYTMID 360
  361 IDNGIDDIIK ENIVENISKI TGVVAVRMIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.30103
Match:	1psdA
Description:	Phosphoglycerate dehydrogenase; Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	3.48670706716817	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.1980358206838	bayes_pls_golite062009
oxidoreductase activity	1.69771604880532	bayes_pls_golite062009
binding	1.09846595911524	bayes_pls_golite062009
catalytic activity	0.645256181736122	bayes_pls_golite062009
phosphoglycerate dehydrogenase activity	0.639509916626856	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
transcription regulator activity	0.402429890233999	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
protein binding	0.219210115869644	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: