YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30257174, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	262 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30257174, gi|....

Description	E-value	Query Range	Subject Range
gi\|20807045, gi\|... - gi\|20807045\|ref\|NP_622216.1\| 3-hydroxybutyryl-CoA dehydratase [Thermoanaerobacter tengcongensis MB4]... gi\|20807045 - gi\|20807045\|ref\|NP_622216.1\| enoyl-CoA hydratase [Thermoanaerobacter tengcongensis MB4]	6.0E-83	[2..261]	[1..259]
gi\|88926146, gi\|... - gi\|88944140\|ref\|ZP_01147473.1\| putative crotonase [Desulfotomaculum reducens MI-1], gi\|88926146\|gb\|E...	3.0E-80	[2..262]	[1..260]
gi\|77997022, gi\|... - gi\|78044907\|ref\|YP_360429.1\| 3-hydroxybutyryl-CoA dehydratase [Carboxydothermus hydrogenoformans Z-2...	6.0E-80	[2..262]	[1..260]
gi\|18145966, gi\|... - gi\|18311283\|ref\|NP_563217.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens str. 13], gi\|... gi\|110673862, gi... - gi\|110799215\|ref\|YP_696975.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens ATCC 13124],... gi\|182625533, gi... - gi\|182625533\|ref\|ZP_02953304.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens D str. JGS... gi\|170715197, gi... - gi\|170715197\|gb\|EDT27379.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens CPE str. F4969...	4.0E-79	[2..262]	[1..260]
gi\|1903327 - gi\|1903327\|emb\|CAB07495.1\| crotonase [Thermoanaerobacterium thermosaccharolyticum] gi\|1903327\|emb\|C... - crotonase [Thermoanaerobacterium thermosaccharolyticum]	6.0E-79	[2..262]	[1..259]
gi\|110683900, gi... - gi\|110803399\|ref\|YP_699562.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens SM101], gi\|1...	9.0E-79	[2..262]	[1..260]
gi\|28202663, gi\|... - gi\|28210227\|ref\|NP_781171.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium tetani E88], gi\|28202663\|...	1.0E-78	[4..261]	[1..257]
gi\|170710479, gi... - gi\|170710479\|gb\|EDT22661.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens B str. ATCC 36... gi\|169342207, gi... - gi\|169342207\|ref\|ZP_02863292.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens C str. JGS... gi\|110675768, gi... - gi\|110801121\|ref\|YP_694554.1\| 3-hydroxybutyryl-CoA dehydratase [Clostridium perfringens ATCC 13124],...	6.0E-77	[4..262]	[1..258]

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Predicted Domain #1

Region A:
Residues: [1-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQLQNISVD YATPHVVKIS LNRERQANSL SLALLEELQN ILTQINEEAN TRVVILTGAG  60
   61 EKAFCAGADL KERAGMNEEQ VRHAVSMIRT TMEMVEQLPQ PVIAAINGIA LGGGTELSLA 120
  121 CDFRIAAESA SLGLTETTLA IIPGAGGTQR LPRLIGVGRA KELIYTGRRI SAQEAKEYGL 180
  181 VEFVVPVHLL EEKAIEIAEK IASNGPIAVR LAKEAISNGI QVDLHTGLQM EKQAYEGVIH 240
  241 TKDRLEGLQA FKEKRTPMYK GE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.39794
Match:	1dubA
Description:	Enoyl-CoA hydratase (crotonase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
enoyl-CoA hydratase activity	3.92947460544831	bayes_pls_golite062009
CoA carboxylase activity	3.59076614105466	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	3.4980371783229	bayes_pls_golite062009
acetyl-CoA carboxylase activity	3.34692152434862	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	2.44182589784656	bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity	1.80820904754223	bayes_pls_golite062009
catalytic activity	1.46154163027498	bayes_pls_golite062009
propionyl-CoA carboxylase activity	1.20853698666984	bayes_pls_golite062009
ligase activity	0.98581896521131	bayes_pls_golite062009
binding	0.578223105269736	bayes_pls_golite062009
3-hydroxybutyryl-CoA epimerase activity	0.241955774397835	bayes_pls_golite062009
racemase and epimerase activity, acting on hydroxy acids and derivatives	0.099208209617217	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds	0.0918189681606029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: