YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30256987, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	302 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30256987, gi|....

Description	E-value	Query Range	Subject Range
gi\|229133183, gi... - gi\|229133183\|ref\|ZP_04262016.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus BD... gi\|163862320, gi... - gi\|89205510\|ref\|ZP_01184079.1\| Isocitrate lyase and phosphorylmutase [Bacillus weihenstephanensis KB...	1.0E-83	[1..302]	[1..302]
gi\|74489528, gi\|... - gi\|75762982\|ref\|ZP_00742779.1\| Methylisocitrate lyase [Bacillus thuringiensis serovar israelensis AT...	2.0E-83	[1..302]	[1..302]
gi\|47557342, gi\|... - gi\|47565706\|ref\|ZP_00236746.1\| methylisocitrate lyase [Bacillus cereus G9241], gi\|47557342\|gb\|EAL156... gi\|217066446, gi... - gi\|217959849\|ref\|YP_002338405.1\| methylisocitrate lyase [Bacillus cereus AH187], gi\|217066446\|gb\|ACJ... gi\|228644398, gi... - gi\|229139043\|ref\|ZP_04267620.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus BD...	2.0E-83	[1..302]	[1..302]
gi\|118477757, gi... - gi\|118477757\|ref\|YP_894908.1\| 2,3-dimethylmalate lyase [Bacillus thuringiensis str. Al Hakam], gi\|11... gi\|228927408, gi... - gi\|228927408\|ref\|ZP_04090465.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus thuringie... gi\|49479982, gi\|... - gi\|49479982\|ref\|YP_036454.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus thuringiensi... gi\|225864315, gi... - gi\|225864315\|ref\|YP_002749693.1\| methylisocitrate lyase [Bacillus cereus 03BB102], gi\|225790387\|gb\|A... gi\|218536956, gi... - gi\|218903485\|ref\|YP_002451319.1\| methylisocitrate lyase [Bacillus cereus AH820], gi\|218536956\|gb\|ACK... gi\|196025954, gi... - gi\|196043645\|ref\|ZP_03110883.1\| methylisocitrate lyase [Bacillus cereus 03BB108], gi\|196025954\|gb\|ED... gi\|196039879, gi... - gi\|196039879\|ref\|ZP_03107182.1\| methylisocitrate lyase [Bacillus cereus NVH0597-99], gi\|196029138\|gb... gi\|228661548, gi... - gi\|229121899\|ref\|ZP_04251118.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus 95... gi\|195993557, gi... - gi\|196033877\|ref\|ZP_03101288.1\| methylisocitrate lyase [Bacillus cereus W], gi\|195993557\|gb\|EDX57514... gi\|228691957, gi... - gi\|229091328\|ref\|ZP_04222543.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus Ro... gi\|228945956, gi... - gi\|228945956\|ref\|ZP_04108298.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus thuringie... gi\|228826100, gi... - gi\|228933640\|ref\|ZP_04096490.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus thuringie... gi\|229184562, gi... - gi\|229184562\|ref\|ZP_04311764.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus BG... gi\|51976593, gi\|... - gi\|52143124\|ref\|YP_083704.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus E33L]...	2.0E-83	[1..302]	[1..302]
gi\|42781441, gi\|... - gi\|42781441\|ref\|NP_978688.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus ATCC ...	3.0E-83	[1..302]	[1..302]
gi\|206971672, gi... - gi\|206971672\|ref\|ZP_03232622.1\| methylisocitrate lyase [Bacillus cereus AH1134], gi\|206733657\|gb\|EDZ... gi\|218233893, gi... - gi\|218233893\|ref\|YP_002367034.1\| methylisocitrate lyase [Bacillus cereus B4264], gi\|218161850\|gb\|ACK... gi\|229109773, gi... - gi\|229109773\|ref\|ZP_04239358.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus Ro... gi\|229083242, gi... - gi\|229083242\|ref\|ZP_04215616.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus Ro... gi\|228838596, gi... - gi\|228921050\|ref\|ZP_04084385.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus thuringie... gi\|229178696, gi... - gi\|229178696\|ref\|ZP_04306060.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus 17... gi\|229150553, gi... - gi\|229150553\|ref\|ZP_04278768.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus m1... gi\|228638648, gi... - gi\|229144926\|ref\|ZP_04273323.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus BD... gi\|229127728, gi... - gi\|229127728\|ref\|ZP_04256717.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Bacillus cereus BD... gi\|30020419, gi\|... - gi\|30020419\|ref\|NP_832050.1\| methylisocitrate lyase [Bacillus cereus ATCC 14579], gi\|29895970\|gb\|AAP...	3.0E-83	[1..302]	[1..302]
gi\|89152077, gi\|... - gi\|89199802\|ref\|ZP_01178559.1\| Isocitrate lyase and phosphorylmutase [Bacillus cereus subsp. cytotox...	3.0E-83	[1..302]	[1..302]
gi\|23099722, gi\|... - gi\|23099722\|ref\|NP_693188.1\| carboxyvinyl-carboxyphosphonate phosphorylmutase [Oceanobacillus iheyen...	4.0E-80	[1..300]	[1..300]
PRPB_BACSU - 2-methylisocitrate lyase OS=Bacillus subtilis (strain 168) GN=prpB PE=3 SV=1 gi\|221323855 - gi\|221323855\|ref\|ZP_03605149.1\| hypothetical protein BsubsS_13197 [Bacillus subtilis subsp. subtilis... CPPM_BACSU, PRPB... - Methylisocitrate lyase OS=Bacillus subtilis GN=prpB PE=3 SV=1, Putative carboxyvinyl-carboxyphosphon... gi\|221314656 - gi\|221314656\|ref\|ZP_03596461.1\| hypothetical protein BsubsN3_13147 [Bacillus subtilis subsp. subtili... gi\|221319579 - gi\|221319579\|ref\|ZP_03600873.1\| hypothetical protein BsubsJ_13068 [Bacillus subtilis subsp. subtilis...	5.0E-80	[1..301]	[1..301]
gi\|46915335, gi\|... - gi\|54301915\|ref\|YP_131908.1\| 2-methylisocitrate lyase [Photobacterium profundum SS9], gi\|46915335\|em...	6.0E-80	[13..288]	[2..280]

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Predicted Domain #1

Region A:
Residues: [1-302]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAWVVNKQST QEELANRFRA LVEANEILQI PGAHDAMAAL VARNTGFLAL YLSGAAYTAS  60
   61 KGLPDLGIVT STEVAERARD LVRATDLPVL VDIDTGFGGV LNVARTAVEM VEAKVAAVQI 120
  121 EDQQLPKKCG HLNGKKLVTT EELVQKIKAI KEVAPSLYIV ARTDARGVEG LDEAIERANA 180
  181 YVKAGADAIF PEALQSEEEF RLFNSKVNAP LLANMTEFGK TPYYSAEEFA NMGFQMVIYP 240
  241 VTSLRVAAKA YENVFTLIKE TGSQKDALSN MQTRSELYET ISYHDFEELD TGIAKTVLSE 300
  301 DQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.0
Match:	1mumA
Description:	2-methylisocitrate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.96882793316847	bayes_pls_golite062009
methylisocitrate lyase activity	2.09739770469711	bayes_pls_golite062009
citrate (pro-3S)-lyase activity	0.86095690814621	bayes_pls_golite062009
lyase activity	0.70986506551964	bayes_pls_golite062009
transferase activity	0.5687068385416	bayes_pls_golite062009
oxo-acid-lyase activity	0.404868472347919	bayes_pls_golite062009
carbon-carbon lyase activity	0.36217387205482	bayes_pls_golite062009
carboxyvinyl-carboxyphosphonate phosphorylmutase activity	0.2132734143313	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: