YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261833, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	446 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261833, gi|....

Description	E-value	Query Range	Subject Range
SDHD_BACHK - Probable D-serine dehydratase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=dsdA PE=3... SDHD_BACHK - Probable D-serine dehydratase OS=Bacillus thuringiensis subsp. konkukian GN=dsdA PE=3 SV=1	2.0E-90	[1..446]	[1..446]
SDHD_BACCZ - Probable D-serine dehydratase OS=Bacillus cereus (strain ZK / E33L) GN=dsdA PE=3 SV=1	2.0E-90	[1..446]	[1..446]
gi\|229144445, gi... - gi\|229144445\|ref\|ZP_04272850.1\| D-serine dehydratase [Bacillus cereus BDRD-ST24], gi\|228639076\|gb\|EE... gi\|229127156, gi... - gi\|229127156\|ref\|ZP_04256153.1\| D-serine dehydratase [Bacillus cereus BDRD-Cer4], gi\|228656272\|gb\|EE... SDHD_BACCR - Probable D-serine dehydratase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305...	3.0E-90	[1..443]	[1..443]
gi\|74489262, gi\|... - gi\|75763250\|ref\|ZP_00743005.1\| D-serine dehydratase [Bacillus thuringiensis serovar israelensis ATCC... gi\|228900414, gi... - gi\|228900414\|ref\|ZP_04064642.1\| D-serine dehydratase [Bacillus thuringiensis IBL 4222], gi\|228859212...	2.0E-89	[1..443]	[1..443]
SDHD_BACC1 - Probable D-serine dehydratase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=dsdA PE=3 SV=1	4.0E-89	[1..443]	[1..443]
gi\|47557504, gi\|... - gi\|47565514\|ref\|ZP_00236555.1\| D-serine dehydratase [Bacillus cereus G9241], gi\|47557504\|gb\|EAL15831...	1.0E-88	[1..442]	[1..442]
gi\|229132658, gi... - gi\|229132658\|ref\|ZP_04261505.1\| D-serine dehydratase [Bacillus cereus BDRD-ST196], gi\|228650785\|gb\|E... SDHD_BACWK - Probable D-serine dehydratase OS=Bacillus weihenstephanensis (strain KBAB4) GN=dsdA PE=3 SV=1	7.0E-86	[1..442]	[1..443]
SDHD_BACHD - Probable D-serine dehydratase OS=Bacillus halodurans GN=dsdA PE=3 SV=1 SDHD_BACHD - Probable D-serine dehydratase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / ...	6.0E-84	[1..442]	[1..442]
gi\|189366338, gi... - gi\|189366338\|gb\|EDU84754.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4501], gi\|168763... gi\|188017246, gi... - gi\|188017246\|gb\|EDU55368.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4113], gi\|168748... gi\|13362715, gi\|... - gi\|15832499\|ref\|NP_311272.1\| D-serine dehydratase [Escherichia coli O157:H7 str. Sakai], gi\|13362715... gi\|254593728, gi... - gi\|254794328\|ref\|YP_003079165.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. TW14359], gi\|... gi\|189372865, gi... - gi\|189372865\|gb\|EDU91281.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC869], gi\|1687872... gi\|168780326, gi... - gi\|189001880\|gb\|EDU70866.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4076], gi\|168780... gi\|168772802, gi... - gi\|187771214\|gb\|EDU35058.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4196], gi\|168772... gi\|168770934, gi... - gi\|189360248\|gb\|EDU78667.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4486], gi\|168770... gi\|209747728, gi... - pir\|\|G85878 D-serine dehydratase (deaminase) [imported] - Escherichia coli (strain O157:H7, substrai... gi\|15802909, gi\|... - gi\|15802909\|ref\|NP_288936.1\| D-serine dehydratase [Escherichia coli O157:H7 EDL933], gi\|12516733\|gb\|... SDHD_ECO57 - D-serine dehydratase OS=Escherichia coli O157:H7 GN=dsdA PE=3 SV=1 gi\|208740136, gi... - gi\|208820013\|ref\|ZP_03260333.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4042], gi\|20... gi\|208813879, gi... - gi\|208813879\|ref\|ZP_03255208.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4045], gi\|20... gi\|208727157, gi... - gi\|208807356\|ref\|ZP_03249693.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4206], gi\|20... gi\|195938719 - gi\|195938719\|ref\|ZP_03084101.1\| D-serine dehydratase [Escherichia coli O157:H7 str. EC4024] gi\|217326787, gi... - gi\|217326787\|ref\|ZP_03442870.1\| D-serine ammonia-lyase [Escherichia coli O157:H7 str. TW14588], gi\|2... SDHD_ECO5E - D-serine dehydratase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=dsdA PE=3 SV=1	1.0E-82	[1..439]	[1..442]
gi\|194428614, gi... - gi\|75210158\|ref\|ZP_00710330.1\| COG3048: D-serine dehydratase [Escherichia coli B171], gi\|194428614\|r...	3.0E-82	[1..439]	[1..442]

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Predicted Domain #1

Region A:
Residues: [1-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEIEKLKEE YPLLNKLIEI EEVFWVNPNM EKYETAIKDS PLSEENVKDA EERLKRFASY  60
   61 IAKVFPETKD TGGIIESPLV KIPSMKQSLE KNYEQPILGE LLLKCDSHLP ISGSIKARGG 120
  121 IYEVLKHAEQ LALQQGMLTE EDDYSILDSD TCREFFATYS IAVGSTGNLG LSIGIMSAKL 180
  181 GFNVTVHMSA DAKQWKKDLL RSKGVNVIEY EADYSKAVEE GRRQADADPS CYFVDDENSH 240
  241 DLFLGYAVAA SRLQKQLEEL EIIVDEEHPL FVYLPCGVGG GPGGVAFGLK LLYKDNVHCF 300
  301 FAEPTHSPCM LIGLMTGLHD KIAVQDIGID NVTDADGLAV GRPSGFVGKT MEPFLSGNYT 360
  361 VSDEELYRLL KELADTENIY LEPSALAGMI GPVKVCKEDA YLQEQQLMEK MKKGTHIVWG 420
  421 TGGSMVPEDV MNGYYKTGEA LTILEK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.221849
Match:	1jbqA
Description:	Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cysteine synthase activity	3.05516621034881	bayes_pls_golite062009
catalytic activity	2.76038225023173	bayes_pls_golite062009
lyase activity	2.54165185299539	bayes_pls_golite062009
carbon-oxygen lyase activity	1.52790731142158	bayes_pls_golite062009
ammonia-lyase activity	0.943946746392831	bayes_pls_golite062009
carbon-nitrogen lyase activity	0.8463142805916	bayes_pls_golite062009
L-threonine ammonia-lyase activity	0.57533596285038	bayes_pls_golite062009
tryptophan synthase activity	0.44169275450925	bayes_pls_golite062009
threonine synthase activity	0.19129755094699	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: