YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30255363, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30255363, gi|....

Description	E-value	Query Range	Subject Range
gi\|91204079 - gi\|91204079\|emb\|CAJ71732.1\| strongly similar to 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methy...	3.0E-45	[1..235]	[1..235]
gi\|133727944, gi... - gi\|153165862\|ref\|ZP_01926527.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... gi\|254853236 - gi\|254853236\|ref\|ZP_05242584.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... HIS4_LISMF - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|254879539 - gi\|254879539\|ref\|ZP_05252249.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|254993158 - gi\|254993158\|ref\|ZP_05275348.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi...	5.0E-45	[1..235]	[1..235]
gi\|254824163 - gi\|254824163\|ref\|ZP_05229164.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... HIS4_LISMC - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|47018824, gi\|... - gi\|47092829\|ref\|ZP_00230613.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomera... gi\|255521468 - gi\|255521468\|ref\|ZP_05388705.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... HIS4_LISMC - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... gi\|133736118, gi... - gi\|254932161\|ref\|ZP_05265520.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi...	6.0E-45	[1..235]	[1..235]
gi\|114547761, gi... - gi\|114771689\|ref\|ZP_01449093.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|114771689 - gi\|114771689\|ref\|ZP_01449093.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi...	8.0E-45	[1..237]	[1..239]
HIS4_PROM9 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	8.0E-45	[1..236]	[1..239]
HIS4_THEP3 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O... HIS4_THEET - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase -...	1.0E-44	[1..237]	[1..237]
gi\|254911243 - gi\|254911243\|ref\|ZP_05261255.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|47016938, gi\|... - gi\|47094798\|ref\|ZP_00232413.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomera... gi\|153183998, gi... - gi\|254900203\|ref\|ZP_05260127.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|153195198, gi... - gi\|254830451\|ref\|ZP_05235106.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi... gi\|133733370, gi... - gi\|254935571\|ref\|ZP_05267268.1\| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imi...	1.0E-44	[1..235]	[1..235]
HIS4_GEOUR - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	1.0E-44	[1..239]	[1..242]
gi\|45528492, gi\|... - gi\|67920558\|ref\|ZP_00514078.1\| Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomera...	2.0E-44	[1..236]	[1..239]
gi\|196252976, gi... - gi\|196252976\|ref\|ZP_03151621.1\| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomer... HIS4_CLOTH - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase O...	2.0E-44	[1..237]	[1..237]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIFPAIDLK EGRCVRLYQG EFSKETVMNE DPVAQAIIFE KFGAKRLHIV DLDGAVAGES  60
   61 LNLSVIERIC KAVRIPVQVG GGIRSLVAVE KLFSVGVDKV ILGTAALYDK TFLEEAVLLY 120
  121 KEKIIVGIDA KNGFVATRGW LDVSEISYID LAKQMEKIGV QTIVFTDISK DGTLAGPNIE 180
  181 QLELLQKSVA IRLIASGGVA SIQDVKKLND MNIYGVIIGK ALYEKTIDLE EVVEVTKLC

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.0
Match:	1vzwA
Description:	Crystal structure of the bifunctional protein Pria
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.63799159510181	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	1.13340776845419	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	0.549444136526559	bayes_pls_golite062009
tryptophan synthase activity	0.426391242491024	bayes_pls_golite062009
lyase activity	0.258652421339738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: