YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30255360, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	429 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30255360, gi|....

Description	E-value	Query Range	Subject Range
HISX_BACCR - Histidinol dehydrogenase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NC... gi\|229043247, gi... - gi\|229043247\|ref\|ZP_04190969.1\| Histidinol dehydrogenase [Bacillus cereus AH676], gi\|228726108\|gb\|EE... gi\|228656761, gi... - gi\|229126821\|ref\|ZP_04255833.1\| Histidinol dehydrogenase [Bacillus cereus BDRD-Cer4], gi\|228656761\|g...	0.0	[1..429]	[1..429]
HISX_BACCZ - Histidinol dehydrogenase OS=Bacillus cereus (strain ZK / E33L) GN=hisD PE=3 SV=1	0.0	[1..429]	[1..429]
HISX_BACHK - Histidinol dehydrogenase OS=Bacillus thuringiensis subsp. konkukian GN=hisD PE=3 SV=1 HISX_BACHK - Histidinol dehydrogenase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=hisD PE=3 SV=1	0.0	[1..429]	[1..429]
gi\|47556848, gi\|... - gi\|47566295\|ref\|ZP_00237323.1\| histidinol dehydrogenase [Bacillus cereus G9241], gi\|47556848\|gb\|EAL1...	0.0	[1..429]	[1..429]
HISX_BACC1 - Histidinol dehydrogenase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=hisD PE=3 SV=1	0.0	[1..429]	[1..429]
gi\|163861516, gi... - gi\|89207828\|ref\|ZP_01186359.1\| Histidinol dehydrogenase [Bacillus weihenstephanensis KBAB4], gi\|8915...	0.0	[1..429]	[1..429]
gi\|218540585, gi... - gi\|218896437\|ref\|YP_002444848.1\| histidinol dehydrogenase [Bacillus cereus G9842], gi\|218540585\|gb\|A... gi\|75759736, gi\|... - gi\|75759736\|ref\|ZP_00739816.1\| Histidinol dehydrogenase [Bacillus thuringiensis serovar israelensis ... gi\|228859493, gi... - gi\|228900087\|ref\|ZP_04064320.1\| Histidinol dehydrogenase [Bacillus thuringiensis IBL 4222], gi\|22885... gi\|228964473, gi... - gi\|228964473\|ref\|ZP_04125585.1\| Histidinol dehydrogenase [Bacillus thuringiensis serovar sotto str. ...	0.0	[1..429]	[1..429]
gi\|149902664, gi... - gi\|82746331\|ref\|ZP_00908838.1\| Histidinol dehydrogenase [Clostridium beijerincki NCIMB 8052], gi\|827...	0.0	[1..426]	[5..428]
gi\|134052894, gi... - gi\|88945237\|ref\|ZP_01148451.1\| Histidinol dehydrogenase [Desulfotomaculum reducens MI-1], gi\|8892511...	0.0	[1..427]	[1..430]
HISX_CLOAB - Histidinol dehydrogenase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5... HISX_CLOAB - Histidinol dehydrogenase OS=Clostridium acetobutylicum GN=hisD PE=3 SV=1	0.0	[1..426]	[5..431]

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Predicted Domain #1

Region A:
Residues: [1-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIVCEDFQK ALTKIKLLRE NANIIEETVQ RSVREIVQNV RESRDEALSF YTKKFDGVEI  60
   61 KDVRVSEEEI KQASMFVESS FLEALQEAKK NIISYHEKQK RQSMFDCTSK GIIRGQIIRP 120
  121 LENIGVYVPG GTASYPSSVL MNVLPAKLAG VKKIVMVTPP RAGGIDPHIL VAASLAGVDE 180
  181 IYMIGGAQAI AALAYGTESI PKVDKIVGPG NLYVALAKRE VYGIVNIDMI AGPSEIVVIA 240
  241 DETGNAKYIA ADLLSQAEHD ERATAICITT NIELAKEVEK EIERQLETLP RSEIARESIN 300
  301 RNGAIFIVPS IDEALQLSNE IAPEHLELHI KEPMNALAYV KHAGSIFLGP YAPEPLGDYL 360
  361 AGPNHVLPTS GTARFFSPLS VDDFVKKSSF LSYTEGALRD VKHHIVELAN KEGLHAHARA 420
  421 IQIRFGEEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	168.0
Match:	1k75A
Description:	L-histidinol dehydrogenase HisD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.80804701752928	bayes_pls_golite062009
histidinol dehydrogenase activity	2.32012109012499	bayes_pls_golite062009
oxidoreductase activity	2.31275077585879	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.24875477727877	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2.22720948878196	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: