YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30261504, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	420 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30261504, gi|....

Description	E-value	Query Range	Subject Range
gi\|86608180 - gi\|86608180\|ref\|YP_476942.1\| histidyl-tRNA synthetase [Cyanobacteria bacterium Yellowstone B-Prime] gi\|86556722, gi\|... - gi\|86608180\|ref\|YP_476942.1\| histidyl-tRNA synthetase [Synechococcus sp. JA-2-3B'a(2-13)], gi\|865567...	3.0E-66	[5..420]	[3..413]
SYH_SYNEL - Histidyl-tRNA synthetase OS=Synechococcus elongatus GN=hisS PE=3 SV=1 SYH_THEEB - Histidine--tRNA ligase OS=Thermosynechococcus elongatus (strain BP-1) GN=hisS PE=3 SV=1	1.0E-65	[4..419]	[1..410]
SYH_SYNJA - Histidine--tRNA ligase OS=Synechococcus sp. (strain JA-3-3Ab) GN=hisS PE=3 SV=1 gi\|86555657, gi\|... - gi\|86607115\|ref\|YP_475878.1\| histidyl-tRNA synthetase [Cyanobacteria bacterium Yellowstone A-Prime],...	4.0E-65	[5..420]	[3..413]
SYH_SYNE7 - Histidine--tRNA ligase OS=Synechococcus elongatus (strain PCC 7942) GN=hisS PE=3 SV=1	1.0E-63	[1..419]	[1..411]
SYH_PYRAB - Histidyl-tRNA synthetase OS=Pyrococcus abyssi GN=hisS PE=3 SV=1 SYH_PYRAB - Histidine--tRNA ligase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=hisS PE=3 SV=1	7.0E-63	[5..419]	[1..422]
SYH_SYNP6 - Histidine--tRNA ligase OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=hisS PE=...	1.0E-62	[1..419]	[1..411]
SYH_PYRHO - Histidyl-tRNA synthetase OS=Pyrococcus horikoshii GN=hisS PE=3 SV=1 SYH_PYRHO - Histidine--tRNA ligase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 10...	3.0E-62	[5..419]	[1..422]
gi\|114552212, gi... - gi\|114777430\|ref\|ZP_01452427.1\| histidyl-tRNA synthetase [Mariprofundus ferrooxydans PV-1], gi\|11455...	3.0E-62	[1..414]	[1..403]
gi\|45523931, gi\|... - gi\|67924802\|ref\|ZP_00518201.1\| Histidyl-tRNA synthetase, class IIa [Crocosphaera watsonii WH 8501], ...	9.0E-62	[5..418]	[3..410]
SYH_KORVE - Histidine--tRNA ligase OS=Koribacter versatilis (strain Ellin345) GN=hisS PE=3 SV=1	3.0E-61	[5..418]	[1..419]

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Predicted Domain #1

Region A:
Residues: [1-420]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKWKRANPN GTRDYLFEEC TLIEEVEQKL RRTFLERGYE EIRTPTIEFY DVFAFQSRPI  60
   61 DEEKMYKFFD EKGRIIVLRP DMTIPLARVV GTQRCDTPLK VTYSGNVFRA NESLAGKYNE 120
  121 IVQSGIEVIG IDNVRAEIEC VISVIQSLQK LRVQSFTIEI GQVQLYKCIV KKLSIHEEEE 180
  181 KFLRTYIESK NYASLSNFIR DKKLDRCDET VKLLEKLPRL FGNLEVIEEA EKLASSNEMK 240
  241 MAITRVKEIY EAIEKLGYGS YISIDLGTIQ HLDYYTGVIF KGYIYEIGEE IVSGGRYDEL 300
  301 IGNFGEMLPA VGLAVQVNQI VKALQEQQEP YERKRIDIMI HYELNRLAEA ERLRNLLQKD 360
  361 GKKVALSLFS NLNDTFQFAR KNQIVTVVEA KSESLVEYVW KEKWVVQKEG ETSCVTFKLR 420
  421

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.09691
Match:	1kmmA
Description:	Histidyl-tRNA synthetase (HisRS), C-terminal domain; Histidyl-tRNA synthetase (HisRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	7.20130208252979	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.20130208252979	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.18884532579969	bayes_pls_golite062009
ligase activity	6.46734856052643	bayes_pls_golite062009
histidine-tRNA ligase activity	5.63786970034739	bayes_pls_golite062009
catalytic activity	2.36416267096403	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	1.82630084735103	bayes_pls_golite062009
serine-tRNA ligase activity	1.67995723068335	bayes_pls_golite062009
threonine-tRNA ligase activity	1.61348476813499	bayes_pls_golite062009
alanine-tRNA ligase activity	1.37855221028045	bayes_pls_golite062009
lysine-tRNA ligase activity	1.2286808923607	bayes_pls_golite062009
glycine-tRNA ligase activity	1.22845858760023	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.50755166961092	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: