YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30255241, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	455 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30255241, gi|....

Description	E-value	Query Range	Subject Range
gi\|52785994, gi\|... - gi\|52785994\|ref\|YP_091823.1\| DhaS [Bacillus licheniformis ATCC 14580], gi\|52348496\|gb\|AAU41130.1\| Dh...	0.0	[2..433]	[61..498]
gi\|20372798 - gi\|20372798\|emb\|CAD30313.1\| aldehyde dehydrogenase [Geobacillus stearothermophilus]	0.0	[2..429]	[58..491]
gi\|56684572, gi\|... - gi\|56684572\|gb\|AAW21985.1\| RALDH3 [Xenopus laevis], gi\|213626544\|gb\|AAI69603.1\| RALDH3 [Xenopus laev...	0.0	[2..436]	[70..512]
gi\|45382777, gi\|... - gi\|45382777\|ref\|NP_990000.1\| aldehyde dehydrogenase 1A3 [Gallus gallus], gi\|11596123\|gb\|AAG38487.1\| ...	0.0	[2..433]	[70..509]
gi\|221319075 - gi\|221319075\|ref\|ZP_03600369.1\| aldehyde dehydrogenase [Bacillus subtilis subsp. subtilis str. JH642... gi\|221323349 - gi\|221323349\|ref\|ZP_03604643.1\| aldehyde dehydrogenase [Bacillus subtilis subsp. subtilis str. SMY] ALDH4_BACSU - Putative aldehyde dehydrogenase DhaS OS=Bacillus subtilis (strain 168) GN=dhaS PE=3 SV=1 ALDH4_BACSU - Putative aldehyde dehydrogenase dhaS OS=Bacillus subtilis GN=dhaS PE=3 SV=1	0.0	[2..433]	[58..495]
AL1A1_SHEEP - Retinal dehydrogenase 1 OS=Ovis aries GN=ALDH1A1 PE=1 SV=2	0.0	[2..433]	[59..498]
gi\|114659188 - gi\|114659188\|ref\|XP_510621.2\| PREDICTED: aldehyde dehydrogenase 1A3 isoform 5 [Pan troglodytes]	0.0	[2..433]	[42..481]
gi\|2183299 - gi\|2183299\|gb\|AAC51652.1\| aldehyde dehydrogenase 1 [Homo sapiens]	0.0	[2..433]	[59..498]
AL1A1_BOVIN - Retinal dehydrogenase 1 OS=Bos taurus GN=ALDH1A1 PE=2 SV=3	0.0	[2..433]	[59..498]
gi\|197100827 - gi\|197100827\|ref\|NP_001127609.1\| aldehyde dehydrogenase 1A1 [Pongo abelii] gi\|55732507 - gi\|55732507\|emb\|CAH92954.1\| hypothetical protein [Pongo abelii]	0.0	[2..433]	[59..498]

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Predicted Domain #1

Region A:
Residues: [1-455]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVSSIVNKQ KAYFYNGHTR SVEVRKNNLK KLYEGIQRFE EEIFQALKLD LNKSVHESFT  60
   61 TEVGYVLKEI SFQLKHMSSW SKPKRVRTAL THFGSKGKVV PEPYGVTLII APWNYPFQLA 120
  121 IAPLVGALAA GNTIVLKPSE LTPNVSKVIT RMLAELFQEE LVAVVEGGVE ESTALLKEPF 180
  181 DYIFFTGSVG VGKVVMEAAA KQLTPLTLEL GGKSPCIVHK DAKVDVTARR IVWGKFLNAG 240
  241 QTCVAPDYLY VHASVKEQLI EALRHEIAEQ YGNEPLQNEN YVRIVSERHF ERLCRFLQDG 300
  301 QVAIGGNYKR DTLHIEPTVV KDITWQDAVM EDEIFGPILP IIEYENIEEV IDTIQQHPKP 360
  361 LALYVFSEDK EMQKKVTSNI SYGGGCVNDV VYHLATPYLP FGGVGSSGLG SYHGEESFRT 420
  421 FSHYKSILAQ STAFDMKIRY SSTKSALKFI RKLLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	118.0
Match:	1ad3A
Description:	Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	4.47226217021998	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	4.34495776828926	bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity	3.87605237828483	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity	3.64672165191647	bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity	3.37049090049734	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	3.2867555127991	bayes_pls_golite062009
benzaldehyde dehydrogenase activity	2.99564252244797	bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity	2.81851373615334	bayes_pls_golite062009
catalytic activity	2.80804701752928	bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity	2.71501590413507	bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity	2.6673036327943	bayes_pls_golite062009
aldehyde dehydrogenase [NAD(P)+] activity	2.43250909158896	bayes_pls_golite062009
malonate-semialdehyde dehydrogenase (acetylating) activity	1.75951883819887	bayes_pls_golite062009
retinal dehydrogenase activity	1.42867174920845	bayes_pls_golite062009
binding	1.06673666884196	bayes_pls_golite062009
retinoid binding	0.983782635681687	bayes_pls_golite062009
isoprenoid binding	0.900374761028287	bayes_pls_golite062009
protein binding	0.894945263794726	bayes_pls_golite062009
glutamate-5-semialdehyde dehydrogenase activity	0.882678635212924	bayes_pls_golite062009
electron carrier activity	0.869224905025397	bayes_pls_golite062009
hydrolase activity	0.799513645745266	bayes_pls_golite062009
histidinol dehydrogenase activity	0.258030369394064	bayes_pls_golite062009
benzaldehyde dehydrogenase (NAD+) activity	0.23487570676521	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: