YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30254728, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	111 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30254728, gi|....

Description	E-value	Query Range	Subject Range
gi\|189025768, gi... - gi\|189025768\|ref\|YP_001933540.1\| anti-sigma F factor antagonist [Treponema pallidum subsp. pallidum ... gi\|7520906 - pir\|\|A71312 probable anti-sigma F factor antagonist (spoIIAA-2) - syphilis spirochete gi\|15639529, gi\|... - gi\|3322830\|gb\|AAC65524.1\| anti-sigma F factor antagonist (spoIIAA-2) [Treponema pallidum subsp. pall...	3.0E-22	[1..111]	[1..111]
gi\|15895575, gi\|... - gi\|15895575\|ref\|NP_348924.1\| anti-anti-sigma factor (antagonist of SpoIIAB) [Clostridium acetobutyli... gi\|25299040 - pir\|\|E97184 anti-anti-sigma factor (antagonist of SpoIIAB) [imported] - Clostridium acetobutylicum	5.0E-22	[3..109]	[1..108]
gi\|88931500, gi\|... - gi\|88931500\|ref\|ZP_01137194.1\| Anti-sigma factor antagonist [Acidothermus cellulolyticus 11B], gi\|88...	7.0E-22	[1..110]	[1..110]
gi\|111153440, gi... - gi\|111225908\|ref\|YP_716702.1\| anti-sigma-B factor antagonist (anti-anti-sigma-B factor) [Frankia aln...	8.0E-22	[1..110]	[1..110]
gi\|86569839, gi\|... - gi\|86742977\|ref\|YP_483377.1\| anti-sigma-factor antagonist domain-containing protein [Frankia sp. CcI...	9.0E-22	[1..110]	[1..110]
gi\|158312176, gi... - gi\|68229180\|ref\|ZP_00568377.1\| Anti-sigma factor antagonist [Frankia sp. EAN1pec], gi\|68203136\|gb\|EA...	2.0E-21	[1..110]	[1..110]
gi\|220931544, gi... - gi\|89210648\|ref\|ZP_01189035.1\| Anti-sigma factor antagonist [Halothermothrix orenii H 168], gi\|89159...	2.0E-21	[3..110]	[1..109]
gi\|48835211 - ref\|ZP_00292212.1\| COG1366: Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) [The... gi\|71914258, gi\|... - gi\|72160526\|ref\|YP_288183.1\| anti-sigma factor antagonist [Thermobifida fusca YX], gi\|71914258\|gb\|AA...	5.0E-21	[1..111]	[1..111]
SP2AA_BACME - Anti-sigma F factor antagonist OS=Bacillus megaterium GN=spoIIAA PE=3 SV=1	5.0E-21	[1..111]	[1..112]
gi\|29831157, gi\|... - gi\|29831157\|ref\|NP_825791.1\| anti-sigma factor antagonist [Streptomyces avermitilis MA-4680], gi\|296...	5.0E-21	[1..110]	[1..110]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLGINILQN DVGYTVQLNG EIDAYTASDL KNKIMPIASE KEVRIVVDFN KVDYMDSTGL  60
   61 GVFIALLKAV KKNDGKLEFI GVSKRLKRLF DITGLTEILN LNSDFEKVER R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.221849
Match:	1th8B
Description:	Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.51984028488182	bayes_pls_golite062009
protein binding	0.99113615143823	bayes_pls_golite062009
transcription regulator activity	0.893093767470901	bayes_pls_golite062009
antisigma factor binding	0.52065892308738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: