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View Structure Prediction Details

Protein: gi|30254223, gi|...
Organism: Bacillus anthracis str. Ames
Length: 396 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30254223, gi|....

Description E-value Query
Range
Subject
Range
gi|89098413, gi|... - gi|89098413|ref|ZP_01171297.1| 8-amino-7-oxononanoate synthase [Bacillus sp. NRRL B-14911], gi|89086...
3.0E-84 [1..396] [1..396]
BIKB_OCEIH, KBL_... - 2-amino-3-ketobutyrate coenzyme A ligase OS=Oceanobacillus iheyensis GN=kbl PE=3 SV=1, Putative 8-am...
PPAT_OCEIH - Putative pyridoxal phosphate-dependent acyltransferase OS=Oceanobacillus iheyensis (strain DSM 14371...
4.0E-81 [1..396] [1..396]
BIOF_THEPX - 8-amino-7-oxononanoate synthase OS=Thermoanaerobacter sp. (strain X514) GN=Teth514_0779 PE=3 SV=1
gi|242258126, gi... - gi|242258126|ref|ZP_04802958.1| pyridoxal phosphate-dependent acyltransferase [Thermoanaerobacter sp...
1.0E-80 [1..396] [1..395]
gi|221238428, gi... - gi|222094371|ref|YP_002528430.1| 8-amino-7-oxononanoate synthase (7-keto-8-amino-pelargonic acid syn...
gi|42779766, gi|... - gi|42779766|ref|NP_977013.1| 2-amino-3-ketobutyrate coenzyme A ligase [Bacillus cereus ATCC 10987], ...
1.0E-80 [1..396] [1..396]
gi|241884087, gi... - gi|241903572|ref|ZP_04788294.1| pyridoxal phosphate-dependent acyltransferase [Thermoanaerobacter br...
BIOF_THEP3 - 8-amino-7-oxononanoate synthase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) GN=...
1.0E-80 [1..396] [1..395]
gi|152974361, gi... - gi|89201547|ref|ZP_01180286.1| Pyridoxal phosphate-dependent acyltransferase, putative [Bacillus cer...
3.0E-80 [1..396] [1..396]
gi|85695191, gi|... - gi|85710787|ref|ZP_01041848.1| 2-amino-3-ketobutyrate coenzyme A ligase [Idiomarina baltica OS145], ...
4.0E-80 [1..396] [1..396]
PPAT_STAAN - Putative pyridoxal phosphate-dependent acyltransferase OS=Staphylococcus aureus (strain N315) GN=SA0...
gi|255005344 - gi|255005344|ref|ZP_05143945.2| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subs...
PPAT_STAAW - Putative pyridoxal phosphate-dependent acyltransferase OS=Staphylococcus aureus (strain MW2) GN=MW05...
PPAT_STAAM - Putative pyridoxal phosphate-dependent acyltransferase OS=Staphylococcus aureus (strain Mu50 / ATCC ...
gi|269202173|ref... - 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subsp. aureus ED98]
gi|251803001, gi... - gi|251813499|ref|ZP_04827972.1| glycine C-acetyltransferase [Staphylococcus aureus subsp. aureus TCH...
gi|253315660 - gi|253315660|ref|ZP_04838873.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subs...
PPAT_STAAS - Putative pyridoxal phosphate-dependent acyltransferase OS=Staphylococcus aureus (strain MSSA476) GN=...
gi|150393057, gi... - gi|90582724|ref|ZP_01238487.1| Pyridoxal phosphate-dependent acyltransferase, putative [Staphylococc...
gi|253731155, gi... - gi|253731155|ref|ZP_04865320.1| glycine C-acetyltransferase [Staphylococcus aureus subsp. aureus USA...
gi|90585436, gi|... - gi|90585436|ref|ZP_01241146.1| Pyridoxal phosphate-dependent acyltransferase, putative [Staphylococc...
gi|253729487, gi... - gi|253732558|ref|ZP_04866723.1| glycine C-acetyltransferase [Staphylococcus aureus subsp. aureus TCH...
5.0E-80 [4..396] [3..395]
gi|47458743, gi|... - gi|47459413|ref|YP_016275.1| 2-amino-3-ketobutyrate coenzyme A ligase [Mycoplasma mobile 163K], gi|4...
6.0E-80 [2..396] [4..398]
gi|87162079|ref|... - putative pyridoxal phosphate-dependent acyltransferase [Staphylococcus aureus subsp. aureus USA300],...
gi|88194312, gi|... - gi|88194312|ref|YP_499104.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subsp. ...
gi|151220724, gi... - gi|151220724|ref|YP_001331546.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus sub...
gi|87162079, gi|... - gi|87162079|ref|YP_493238.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subsp. ...
gi|221141013 - gi|221141013|ref|ZP_03565506.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subs...
gi|221139622 - gi|221139622|ref|ZP_03564421.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus subs...
PPAT_STAAC - Putative pyridoxal phosphate-dependent acyltransferase OS=Staphylococcus aureus (strain COL) GN=SACO...
gi|160367598, gi... - gi|161508789|ref|YP_001574448.1| 2-amino-3-ketobutyrate coenzyme A ligase [Staphylococcus aureus sub...
6.0E-80 [4..396] [3..395]

Back

Predicted Domain #1
Region A:
Residues: [1-396]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKTLAKFL EENLEDLKSK GLYNVIDPLE SSNGPIITIG GKEYINLSSN NYLGLATDSR  60
   61 LQEAAIGAIH KYGVGAGAVR TINGTLDLHI KLEETIAKFK HTEAAIAYQS GFNCNMAAIS 120
  121 AVMDKNDAIL SDELNHASII DGSRLSKAKI IVYKHSDMED LRQKAIAAKE SGLYNKLMVI 180
  181 TDGVFSMDGD VAKLPEIVEI AEELDLMTYV DDAHGSGVLG KGAGTVKHFG LSDKVDFQIG 240
  241 TLSKAIGVIG GYVAGKQNLI DWLKVRSRPF LFSTAVTPAD AAACMRSIEI LMESTELHDR 300
  301 LWENGRYLKQ GLKELGFNIG ESETPITPCI IGDEVLTQEF SKRLNEEGVY AKSIVFPTVA 360
  361 KGTGRVRNMP TAAHTKEMLD EAIRKYEKVG KEMGII

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 73.30103
Match: 1fc4A
Description: 2-amino-3-ketobutyrate CoA ligase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
5-aminolevulinate synthase activity 3.15163480353521 bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity 2.82458180884712 bayes_pls_golite062009
catalytic activity 2.29878871754893 bayes_pls_golite062009
N-succinyltransferase activity 1.81799375593294 bayes_pls_golite062009
threonine aldolase activity 1.80396420390785 bayes_pls_golite062009
adenosylmethionine-8-amino-7-oxononanoate transaminase activity 1.74778109525713 bayes_pls_golite062009
glycine dehydrogenase (decarboxylating) activity 1.63055151623667 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.63055151623667 bayes_pls_golite062009
transferase activity, transferring nitrogenous groups 1.28316822767388 bayes_pls_golite062009
transaminase activity 1.24990480711889 bayes_pls_golite062009
glycine C-acetyltransferase activity 0.935794708043259 bayes_pls_golite062009
transferase activity 0.737426388870721 bayes_pls_golite062009
carbon-sulfur lyase activity 0.698312655247044 bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups 0.659071155545801 bayes_pls_golite062009
transferase activity, transferring acyl groups 0.319452731970428 bayes_pls_golite062009
cystathionine beta-lyase activity 0.15938456446406 bayes_pls_golite062009
sulfurtransferase activity 0.0450490929307473 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle