YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS7_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	195 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS7_GEOSL.

Description	E-value	Query Range	Subject Range
HIS5B_ARATH - Imidazoleglycerol-phosphate dehydratase 2, chloroplastic OS=Arabidopsis thaliana GN=HISN5B PE=1 SV=2	333.0	[0..2]	[195..75]
HIS7_CLOTH - Imidazoleglycerol-phosphate dehydratase OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / ... gi\|196252973, gi... - gi\|196252973\|ref\|ZP_03151618.1\| Imidazoleglycerol-phosphate dehydratase [Clostridium thermocellum DS...	329.0	[0..1]	[195..1]
gi\|75909492, gi\|... - gi\|75909492\|ref\|YP_323788.1\| imidazoleglycerol-phosphate dehydratase [Anabaena variabilis ATCC 29413...	328.0	[0..1]	[195..39]
HIS7_GEOMG - Imidazoleglycerol-phosphate dehydratase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DS...	328.0	[0..1]	[195..1]
gi\|3982576, gi\|1... - gi\|3982576\|gb\|AAC83458.1\| imidazoleglycerol phosphate dehydratase [Thlaspi goesingense], pir\|\|T48893...	326.0	[0..2]	[195..77]
HIS7_GEOUR - Imidazoleglycerol-phosphate dehydratase OS=Geobacter uraniireducens (strain Rf4) GN=hisB PE=3 SV=1	326.0	[0..1]	[195..1]
HIS7_CHESB - Imidazoleglycerol-phosphate dehydratase OS=Chelativorans sp. (strain BNC1) GN=hisB PE=3 SV=1	326.0	[0..3]	[195..7]
gi\|91070624 - gi\|91070624\|gb\|ABE11523.1\| imidazoleglycerol-phosphate dehydratase [uncultured Prochlorococcus marin...	325.0	[0..3]	[195..22]
HIS7_AZOVD - Imidazoleglycerol-phosphate dehydratase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=his... gi\|67154757, gi\|... - gi\|67154757\|ref\|ZP_00416502.1\| Imidazoleglycerol-phosphate dehydratase [Azotobacter vinelandii AvOP]...	324.0	[0..3]	[195..4]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRKATIERV TKETQIKLSL EIDGTGEAKI CTSVPFLDHM LDLFARHGLF NLQVDATGDI  60
   61 DIDFHHTVED IGIVLGQALK EALGDKKGIR RYGQATVPMD ETLASVAVDI SGRPYLVYHV 120
  121 SLPKVKIGEF DVELVREFFQ AVVNNLGANI HVNVMYGDNV HHIVEACFKA FARAVDQATQ 180
  181 VDSRIQGVMS TKGKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	87.154902
Match:	2f1dA
Description:	X-Ray Structure of imidazoleglycerol-phosphate dehydratase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate dehydratase activity	1.6337728630325	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
nucleic acid binding	0.369771518688522	bayes_pls_golite062009
structural constituent of ribosome	0.325699575011026	bayes_pls_golite062009
transcription regulator activity	0.212099606954236	bayes_pls_golite062009
structural molecule activity	2.19428886088058E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: