YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39998085, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39998085, gi|....

Description	E-value	Query Range	Subject Range
CBIF_METJA - Cobalt-precorrin-4 C(11)-methyltransferase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM... CBIF_METJA - Probable cobalt-precorrin-4 C(11)-methyltransferase OS=Methanocaldococcus jannaschii GN=cbiF PE=3 SV...	265.0	[0..4]	[260..1]
gi\|29895119, gi\|... - gi\|30019575\|ref\|NP_831206.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 14579], gi\|2... gi\|229043267, gi... - gi\|229043267\|ref\|ZP_04190989.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus AH676], gi... gi\|229144126, gi... - gi\|229144126\|ref\|ZP_04272541.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus BDRD-ST24]... gi\|229126841, gi... - gi\|229126841\|ref\|ZP_04255853.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus BDRD-Cer4]... gi\|228674452, gi... - gi\|229108983\|ref\|ZP_04238584.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus Rock1-15],...	264.0	[0..8]	[246..3]
gi\|42736543, gi\|... - gi\|42780623\|ref\|NP_977870.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus ATCC 10987], gi\|4...	262.0	[0..8]	[246..2]
gi\|228651038, gi... - gi\|229132332\|ref\|ZP_04261186.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus BDRD-ST196... gi\|89154233, gi\|... - gi\|89207808\|ref\|ZP_01186339.1\| Uroporphyrin-III C-methyltransferase, C-terminal [Bacillus weihenstep...	262.0	[0..8]	[246..2]
gi\|75760415, gi\|... - gi\|75760415\|ref\|ZP_00740458.1\| Uroporphyrin-III C-methyltransferase [Bacillus thuringiensis serovar ...	261.0	[0..8]	[246..3]
gi\|196158491, gi... - gi\|88794338\|ref\|ZP_01110047.1\| uroporphyrin-III C-methyltransferase [Alteromonas macleodii 'Deep eco...	260.0	[0..8]	[245..236]
gi\|47566316, gi\|... - gi\|47566316\|ref\|ZP_00237344.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus G9241], gi\|4755...	260.0	[0..8]	[246..2]
gi\|172082779, gi... - gi\|177651501\|ref\|ZP_02934290.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A0174]... gi\|190568070, gi... - gi\|190568070\|ref\|ZP_03020980.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis Tsiankovski... gi\|49481078, gi\|... - gi\|49481078\|ref\|YP_035642.1\| uroporphyrin-III C-methyltransferase [Bacillus thuringiensis serovar ko... gi\|195992114, gi... - gi\|196035437\|ref\|ZP_03102842.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus W], gi\|1959921... gi\|49184352, gi\|... - gi\|49184352\|ref\|YP_027604.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Sterne], ... gi\|196021838, gi... - gi\|196047327\|ref\|ZP_03114541.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus 03BB108], gi\|1... gi\|218902634, gi... - gi\|218902634\|ref\|YP_002450468.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus AH820], gi\|21... gi\|165870438, gi... - gi\|165870438\|ref\|ZP_02215093.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A0488]... gi\|47501868, gi\|... - gi\|47526720\|ref\|YP_018069.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. 'Ames Anc... gi\|167530326, gi... - gi\|167634438\|ref\|ZP_02392759.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A0442]... gi\|30261524, gi\|... - gi\|30261524\|ref\|NP_843901.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Ames], gi... gi\|167512791, gi... - gi\|167639352\|ref\|ZP_02397624.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A0193]... gi\|65318791, gi\|... - gi\|65318791\|ref\|ZP_00391750.1\| COG0007: Uroporphyrinogen-III methylase [Bacillus anthracis str. A201... gi\|170686835, gi... - gi\|170686835\|ref\|ZP_02878055.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A0465]... gi\|170706209, gi... - gi\|170706209\|ref\|ZP_02896670.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A0389]... gi\|227006993, gi... - gi\|227815726\|ref\|YP_002815735.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. CDC 6... gi\|228845553, gi... - gi\|228914100\|ref\|ZP_04077720.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus thuringiensis ser... gi\|228814568, gi... - gi\|228945124\|ref\|ZP_04107484.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus thuringiensis ser... gi\|228599764, gi... - gi\|229183721\|ref\|ZP_04310941.1\| Uroporphyrinogen-III C-methyltransferase [Bacillus cereus BGSC 6E1],... gi\|229603342, gi... - gi\|229603342\|ref\|YP_002865937.1\| uroporphyrinogen-III C-methyltransferase [Bacillus anthracis str. A... gi\|254682411 - gi\|254682411\|ref\|ZP_05146272.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. CNEVA-... gi\|254726075 - gi\|254726075\|ref\|ZP_05187857.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. A1055] gi\|254733827 - gi\|254733827\|ref\|ZP_05191541.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Wester... gi\|254740481 - gi\|254740481\|ref\|ZP_05198172.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Kruger... gi\|254753872 - gi\|254753872\|ref\|ZP_05205907.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Vollum... gi\|254758967 - gi\|254758967\|ref\|ZP_05210994.1\| uroporphyrin-III C-methyltransferase [Bacillus anthracis str. Austra...	260.0	[0..8]	[246..2]
gi\|51977390, gi\|... - gi\|52143921\|ref\|YP_082908.1\| uroporphyrin-III C-methyltransferase [Bacillus cereus E33L], gi\|5197739...	260.0	[0..8]	[246..2]
gi\|27316645, gi\|... - gi\|27469096\|ref\|NP_765733.1\| uroporphyrin-III C-methyltransferase [Staphylococcus epidermidis ATCC 1...	258.0	[0..4]	[245..1]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSVADNPIV HFVGAGPGDA ELITVKGARL LREAKVVVYA GSLVDRELVR TYAPGAEVHD  60
   61 SAALTLEETT ALLARAVADG RRAVRLHTGD PSIYGAIQEQ MVELDRLGIG YEVVPGVTSA 120
  121 FAAAASLKQE LTLPEVSQTV IITRLAGRTP VPERERLAEI ARIGATLVIY LSVGMIEQVV 180
  181 AELLQGAYTP ATPAAVVSRA SWPDEQAVEG TLADIADKVR SSGIGKQAII LVGDVLKARR 240
  241 EGLKARSLLY DGGFSHEFRT GIIT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.221849
Match:	2cbfA
Description:	THE X-RAY STRUCTURE OF A COBALAMIN BIOSYNTHETIC ENZYME, COBALT PRECORRIN-4 METHYLTRANSFERASE, CBIF, FROM BACILLUS MEGATERIUM, WITH THE HIS-TAG CLEAVED OFF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uroporphyrin-III C-methyltransferase activity	3.573271502205	bayes_pls_golite062009
C-methyltransferase activity	3.35393353163232	bayes_pls_golite062009
precorrin-4 C11-methyltransferase activity	2.18371138649366	bayes_pls_golite062009
catalytic activity	1.48349578618275	bayes_pls_golite062009
transferase activity	0.912524944496351	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.431791521097299	bayes_pls_golite062009
methyltransferase activity	0.424918406685891	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.28351517300952	bayes_pls_golite062009
uroporphyrinogen-III synthase activity	0.00871858903098705	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: