YRC Public Data Repository - Protein Structure Prediction

Protein:	FABZ_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	150 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABZ_GEOSL.

Description	E-value	Query Range	Subject Range
FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum GN=fabZ PE=3 SV=1 FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum (strain SS9) GN=fa...	196.0	[0..2]	[146..5]
gi\|90413540, gi\|... - gi\|90413540\|ref\|ZP_01221531.1\| (3R)-hydroxymyristoyl ACP dehydratase [Photobacterium profundum 3TCK]...	196.0	[0..2]	[146..5]
FABZ_VIBFM - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio fischeri (strain MJ11) GN=fabZ PE=3 ... FABZ_VIBF1 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio fischeri (strain ATCC 700601 / ES114...	194.0	[0..2]	[146..5]
gi\|84376882, gi\|... - gi\|84389781\|ref\|ZP_00991333.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio splendidus 12B01], gi\|8...	193.0	[0..2]	[146..5]
gi\|89075409, gi\|... - gi\|89075409\|ref\|ZP_01161826.1\| (3R)-hydroxymyristoyl ACP dehydratase [Photobacterium sp. SKA34], gi\|...	193.0	[0..2]	[145..5]
FABZ_VIBTL - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio tasmaniensis (strain LGP32) GN=fabZ ... gi\|86146878, gi\|... - gi\|86146878\|ref\|ZP_01065197.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio sp. MED222], gi\|8583533...	193.0	[0..2]	[146..5]
gi\|91191570, gi\|... - gi\|91223484\|ref\|ZP_01258749.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio alginolyticus 12G01], g...	193.0	[0..2]	[146..5]
gi\|254225762, gi... - gi\|75820858\|ref\|ZP_00750896.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ... FABZ_VIBCM - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae serotype O1 (strain M66-2) ... FABZ_VIBC3 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae serotype O1 (strain ATCC 39... gi\|229349072, gi... - gi\|229513891\|ref\|ZP_04403353.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229355182, gi... - gi\|229507677\|ref\|ZP_04397182.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229524251, gi... - gi\|229524251\|ref\|ZP_04413656.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229522195, gi... - gi\|229522195\|ref\|ZP_04411612.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229332522, gi... - gi\|229528748\|ref\|ZP_04418138.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|121549521, gi... - gi\|121586255\|ref\|ZP_01676045.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|124119779, gi... - gi\|153221250\|ref\|ZP_01952265.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|183012862, gi... - gi\|183179451\|ref\|ZP_02957662.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|153213814, gi... - gi\|153213814\|ref\|ZP_01949022.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|126512347, gi... - gi\|153817079\|ref\|ZP_01969746.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|153825348, gi... - gi\|153825348\|ref\|ZP_01978015.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... tr\|B2D710\|B2D710... - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae MZO-3 GN=fabZ PE=3 SV=1, 3-...	192.0	[0..2]	[146..8]
gi\|90437860, gi\|... - gi\|90580982\|ref\|ZP_01236783.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio angustum S14], gi\|90437...	192.0	[0..2]	[145..5]
FABZ_VIBCH - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae serotype O1 (strain ATCC 39... gi\|254845084, gi... - gi\|75831252\|ref\|ZP_00760517.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ... FABZ_VIBCH - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Vibrio cholerae GN=fabZ PE=3 SV=1 gi\|229512128, gi... - gi\|229512128\|ref\|ZP_04401607.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229369836, gi... - gi\|229607181\|ref\|YP_002877829.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio ch... gi\|229519263, gi... - gi\|229519263\|ref\|ZP_04408706.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho...	191.0	[0..2]	[146..8]

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Predicted Domain #1

Region A:
Residues: [1-150]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METVFDINEI MKILPHRYPF LLVDRIVEYV AGERIVGIKN VSINEPFFQG HFPGHPVMPG  60
   61 VLIVEAMAQV GGIYAYVTLG DEVRDKVCYF ASIDNVKFRK PVVPGDQLRI EVTISGCKRG 120
  121 IWCFSARATV NGKLVTEAEL KATFADKEKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.0
Match:	1u1zA
Description:	The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
CoA hydrolase activity	1.75530090056705	bayes_pls_golite062009
catalytic activity	1.11649534052993	bayes_pls_golite062009
thiolester hydrolase activity	0.65794221902015	bayes_pls_golite062009
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.24094527143225	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: