YRC Public Data Repository - Protein Structure Prediction

Protein:	APT_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	171 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APT_GEOSL.

Description	E-value	Query Range	Subject Range
APT1_WHEAT - Adenine phosphoribosyltransferase 1 OS=Triticum aestivum GN=APT1 PE=2 SV=1	173.0	[0..1]	[170..7]
gi\|9711921 - gi\|9711921\|dbj\|BAB08003.1\| Adenine phosphoribosyltransferase [Hordeum vulgare subsp. vulgare]	172.0	[0..1]	[170..7]
APT_RAT - Adenine phosphoribosyltransferase OS=Rattus norvegicus GN=Aprt PE=1 SV=1	170.0	[0..1]	[171..6]
APT_MASHI - Adenine phosphoribosyltransferase OS=Mastomys hildebrandtii GN=APRT PE=3 SV=1	170.0	[0..1]	[171..6]
APT_CRIGR - Adenine phosphoribosyltransferase OS=Cricetulus griseus GN=APRT PE=3 SV=2 APT_CRILO - (P47952) Adenine phosphoribosyltransferase (EC 2.4.2.7) (APRT)	169.0	[0..1]	[171..6]
APT_STOLO - Adenine phosphoribosyltransferase OS=Stochomys longicaudatus GN=APRT PE=3 SV=1	169.0	[0..1]	[171..6]
APT_HAEIN - Adenine phosphoribosyltransferase OS=Haemophilus influenzae GN=apt PE=3 SV=1 APT_HAEIG - Adenine phosphoribosyltransferase OS=Haemophilus influenzae (strain PittGG) GN=apt PE=3 SV=1 gi\|42631865 - gi\|42631865\|ref\|ZP_00157403.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-... gi\|145271773, gi... - gi\|145639211\|ref\|ZP_01794818.1\| adenine phosphoribosyltransferase [Haemophilus influenzae PittII], g... APT_HAEI8 - Adenine phosphoribosyltransferase OS=Haemophilus influenzae (strain 86-028NP) GN=apt PE=3 SV=1 gi\|144978790, gi... - gi\|145629287\|ref\|ZP_01785086.1\| adenine phosphoribosyltransferase [Haemophilus influenzae 22.1-21], ... APT_HAEIN - Adenine phosphoribosyltransferase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / ... gi\|229810356, gi... - gi\|229846867\|ref\|ZP_04466974.1\| adenine phosphoribosyltransferase [Haemophilus influenzae 7P49H1], g...	169.0	[0..1]	[171..5]
gi\|222523585, gi... - gi\|222523585\|ref\|YP_002568055.1\| adenine phosphoribosyltransferase [Chloroflexus sp. Y-400-fl], gi\|2... APT_CHLAA - Adenine phosphoribosyltransferase OS=Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl...	169.0	[0..2]	[171..4]
APT4_ARATH - Adenine phosphoribosyltransferase 4 OS=Arabidopsis thaliana GN=APT4 PE=1 SV=1	168.0	[0..1]	[171..11]
gi\|42629427 - gi\|42629427\|ref\|ZP_00154974.1\| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-...	168.0	[0..1]	[171..5]

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Predicted Domain #1

Region A:
Residues: [1-171]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDELKNIIRD VPDFPKKGII FKDITTLLAD APSFQRMVDL IAHRYVGKKI SKVVVVEARG  60
   61 FVIGAALAYK LGAGVVLVRK PGKLPSETYS KTYQLEYGSD TLEIHTDAIA KGERVIIADD 120
  121 ILATGGTMAA VVDMVEALGG EIVECCFMAE LEFLGGRKRL PEGKVYSLLT F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.39794
Match:	1oreA
Description:	Human Adenine Phosphoribosyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	4.07252508868782	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
transferase activity	3.88709784255536	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	2.36237864658341	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.6596316647688	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.45489477082258	bayes_pls_golite062009
purine binding	1.3774977535406	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
transcription regulator activity	1.09798789282825	bayes_pls_golite062009
nucleic acid binding	1.07284130528063	bayes_pls_golite062009
DNA binding	0.854593555814443	bayes_pls_golite062009
adenine binding	0.817887117933035	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.691442295634288	bayes_pls_golite062009
transcription factor activity	0.339219342075596	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: