YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39996322, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39996322, gi|....

Description	E-value	Query Range	Subject Range
gi\|125973324, gi... - gi\|67876007\|ref\|ZP_00505065.1\| PAS [Clostridium thermocellum ATCC 27405], gi\|67850331\|gb\|EAM45912.1\|...	234.0	[0..4]	[275..517]
gi\|119865539, gi... - gi\|119946935\|ref\|YP_944615.1\| hybrid sensor and regulator fused [Psychromonas ingrahamii 37], gi\|119...	229.0	[0..7]	[270..540]
gi\|71676531, gi\|... - gi\|71676531\|ref\|ZP_00674272.1\| Guanylate cyclase:Response regulator receiver:ATP-binding region, ATP...	224.0	[0..7]	[277..551]
gi\|82945896, gi\|... - gi\|83311055\|ref\|YP_421319.1\| Signal transduction histidine kinase [Magnetospirillum magneticum AMB-1...	224.0	[0..1]	[272..244]
gi\|71906060, gi\|... - gi\|71906060\|ref\|YP_283647.1\| PAS [Dechloromonas aromatica RCB], gi\|71845681\|gb\|AAZ45177.1\| PAS [Dech...	224.0	[0..1]	[276..503]
gi\|83646376, gi\|... - gi\|83646376\|ref\|YP_434811.1\| Signal transduction histidine kinase [Hahella chejuensis KCTC 2396], gi...	222.0	[0..1]	[270..548]
gi\|93451740, gi\|... - gi\|94268066\|ref\|ZP_01291073.1\| Response regulator receiver [delta proteobacterium MLMS-1], gi\|934517...	221.0	[0..4]	[273..197]
gi\|114566853, gi... - gi\|71541312\|ref\|ZP_00663086.1\| PAS [Syntrophomonas wolfei str. Goettingen], gi\|71492116\|gb\|EAO24426....	220.0	[0..7]	[274..381]

Back

Predicted Domain #1

Region A:
Residues: [1-136]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDKKQLGDL LVEAGIITMK TLERALERQK GSGKRLGQVL EEMGVINGDE LIDALSKQFA  60
   61 FKTVRGFADY AFPPELLALV PQDIAVQKQV FPIKQKDNML ALAVNDPFDV ETIDFLAKKN 120
  121 GVQIIPVLAT RQDLLA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.0
Match:	2c2aA
Description:	Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [137-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIEKHYLHGK AKDSQRQKIL VVEDTPPVAT IIQVALHKEG FDVLLAGDGV EGLKTAVVEK  60
   61 PDLIICDSVM PRMDGFSLMR AVRSNPTIAD TPMILLTSKA TGEDEQRALE AGFIDFIAKP 120
  121 VQPIRIVTRV RRAFDLLKRF K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.0
Match:	1mvoA
Description:	PhoP receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: