YRC Public Data Repository - Protein Structure Prediction

Protein:	RUVC_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	164 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RUVC_GEOSL.

Description	E-value	Query Range	Subject Range
gi\|76811143, gi\|... - gi\|76811143\|ref\|YP_334776.1\| Holliday junction resolvase [Burkholderia pseudomallei 1710b], gi\|76580...	232.0	[0..1]	[163..96]
RUVC_RALSO - Crossover junction endodeoxyribonuclease RuvC OS=Ralstonia solanacearum (strain GMI1000) GN=ruvC PE=... RUVC_RALSO - Crossover junction endodeoxyribonuclease ruvC OS=Ralstonia solanacearum GN=ruvC PE=3 SV=1	231.0	[0..1]	[163..1]
RUVC_VIBVU - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio vulnificus GN=ruvC PE=3 SV=1 RUVC_VIBVU - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio vulnificus (strain CMCP6) GN=ruvC PE=3 SV=1	231.0	[0..2]	[163..3]
RUVC_VIBVY - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio vulnificus (strain YJ016) GN=ruvC PE=3 SV=1	231.0	[0..2]	[163..3]
RUVC_GEOMG - Crossover junction endodeoxyribonuclease RuvC OS=Geobacter metallireducens (strain GS-15 / ATCC 5377...	231.0	[0..1]	[164..1]
RUVC_CUPPJ - Crossover junction endodeoxyribonuclease RuvC OS=Cupriavidus pinatubonensis (strain JMP 134 / LMG 11...	231.0	[0..1]	[163..1]
gi\|83652274, gi\|... - gi\|83718449\|ref\|YP_441796.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia thailandens...	230.0	[0..1]	[163..133]
RUVC_CUPMC - Crossover junction endodeoxyribonuclease RuvC OS=Cupriavidus metallidurans (strain ATCC 43123 / DSM ...	230.0	[0..1]	[163..1]
RUVC_CUPNH - Crossover junction endodeoxyribonuclease RuvC OS=Cupriavidus necator (strain ATCC 17699 / H16 / DSM ...	229.0	[0..1]	[163..1]
gi\|229343533, gi... - gi\|229518844\|ref\|ZP_04408287.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio cholerae RC9],... gi\|229607617, gi... - gi\|229607617\|ref\|YP_002878265.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio cholerae MJ-1... gi\|254848933, gi... - gi\|75828633\|ref\|ZP_00757999.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Vibrio ... RUVC_VIBC3 - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Cl... gi\|75814053, gi\|... - gi\|75814053\|ref\|ZP_00744705.1\| COG0817: Holliday junction resolvasome, endonuclease subunit [Vibrio ... gi\|121591338, gi... - gi\|121591338\|ref\|ZP_01678626.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio cholerae 2740-... gi\|153225607, gi... - gi\|153225607\|ref\|ZP_01954802.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio cholerae MAK 7... gi\|229351670, gi... - gi\|229511705\|ref\|ZP_04401184.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio cholerae B33],... RUVC_VIBCH - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio cholerae GN=ruvC PE=3 SV=1 RUVC_VIBCM - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio cholerae serotype O1 (strain M66-2) GN=ruvC ... RUVC_VIBCH - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El... gi\|229508056, gi... - gi\|229508056\|ref\|ZP_04397561.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio cholerae BX 33...	229.0	[0..3]	[163..4]

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Predicted Domain #1

Region A:
Residues: [1-164]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLGIDPGS RITGYGIIEK IGNRLVHVDN GAIHTDSHRE FALRLHKIYE GLSRVIEEYR  60
   61 PDAMAVEQVF LAHNAQSALK LGQARGAAIV AGVSAGLPVS EYTAMQVKQA VVGYGHARKE 120
  121 QVQQMVKSLL NLPEIAQADA SDALAVAVCH ANSAVMKSVL RSIR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.522879
Match:	1hjrA
Description:	RuvC resolvase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nuclease activity	1.81796593394339	bayes_pls_golite062009
exonuclease activity	1.64964907710028	bayes_pls_golite062009
catalytic activity	1.62277843225829	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.58702937619673	bayes_pls_golite062009
hydrolase activity	1.41857676124086	bayes_pls_golite062009
ribonuclease activity	0.71352601607444	bayes_pls_golite062009
deoxyribonuclease activity	0.63299586096139	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	0.62821439153618	bayes_pls_golite062009
endonuclease activity	0.150927275899469	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: