YRC Public Data Repository - Protein Structure Prediction

Protein:	TRMD_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	245 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRMD_GEOSL.

Description	E-value	Query Range	Subject Range
TRMD_PHOLL - tRNA (guanine-N(1)-)-methyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=trmD PE=3 SV=... TRMD_PHOLL - tRNA (guanine-N(1)-)-methyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 1513...	435.0	[0..1]	[243..1]
TRMD_VIBVU - tRNA (guanine-N(1)-)-methyltransferase OS=Vibrio vulnificus (strain CMCP6) GN=trmD PE=3 SV=1 TRMD_VIBVU - tRNA (guanine-N(1)-)-methyltransferase OS=Vibrio vulnificus GN=trmD PE=3 SV=1 TRMD_VIBVY - tRNA (guanine-N(1)-)-methyltransferase OS=Vibrio vulnificus (strain YJ016) GN=trmD PE=3 SV=1	424.0	[0..1]	[242..1]
TRMD_SHELP - tRNA (guanine-N(1)-)-methyltransferase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=trmD P...	424.0	[0..1]	[239..1]
gi\|228960057, gi... - gi\|228960057\|ref\|ZP_04121721.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus thuringiensis serov... gi\|228805683, gi... - gi\|228954117\|ref\|ZP_04116146.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus thuringiensis serov... gi\|206972754, gi... - gi\|206972754\|ref\|ZP_03233684.1\| tRNA (guanine-N1)-methyltransferase [Bacillus cereus AH1134], gi\|206... gi\|228837024, gi... - gi\|228922595\|ref\|ZP_04085895.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus thuringiensis serov... TRMD_BACC4 - tRNA (guanine-N(1)-)-methyltransferase OS=Bacillus cereus (strain B4264) GN=trmD PE=3 SV=1 gi\|229129117, gi... - gi\|229129117\|ref\|ZP_04258090.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus BDRD-Cer4], ... TRMD_BACCR - tRNA (guanine-N(1)-)-methyltransferase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / N... gi\|229111312, gi... - gi\|229111312\|ref\|ZP_04240865.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus Rock1-15], g... gi\|228702140, gi... - gi\|229081096\|ref\|ZP_04213606.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus Rock4-2], gi... gi\|229071339, gi... - gi\|229071339\|ref\|ZP_04204562.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus F65185], gi\|... gi\|229192010, gi... - gi\|229192010\|ref\|ZP_04318980.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus ATCC 10876],... gi\|228631389, gi... - gi\|229152040\|ref\|ZP_04280235.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus m1550], gi\|2... gi\|228637045, gi... - gi\|229146412\|ref\|ZP_04274783.1\| tRNA (guanine-N(1)-)-methyltransferase [Bacillus cereus BDRD-ST24], ...	423.0	[0..1]	[243..1]
gi\|90438671, gi\|... - gi\|90580369\|ref\|ZP_01236176.1\| tRNA (guanine-N(1)-)-methyltransferase [Vibrio angustum S14], gi\|9043...	422.0	[0..1]	[244..1]
gi\|251810670, gi... - gi\|251810670\|ref\|ZP_04825143.1\| tRNA (guanine-N1)-mehtyltransferase [Staphylococcus epidermidis BCM-... TRMD_STAEP - (Q8CQL4) tRNA (Guanine-N(1)-)-methyltransferase (EC 2.1.1.31) (M1G-methyltransferase) (tRNA [GM37] m... TRMD_STAES - tRNA (guanine-N(1)-)-methyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=trmD PE=...	421.0	[0..1]	[244..1]
gi\|89075047, gi\|... - gi\|89075047\|ref\|ZP_01161488.1\| tRNA (guanine-N(1)-)-methyltransferase [Photobacterium sp. SKA34], gi...	421.0	[0..1]	[244..1]
gi\|91228775, gi\|... - gi\|91228775\|ref\|ZP_01262685.1\| tRNA (guanine-N(1)-)-methyltransferase [Vibrio alginolyticus 12G01], ...	420.0	[0..1]	[244..1]
TRMD_STAEQ - tRNA (guanine-N(1)-)-methyltransferase OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) GN=... gi\|242234031, gi... - gi\|242242523\|ref\|ZP_04796968.1\| tRNA (guanine-N1)-methyltransferase [Staphylococcus epidermidis W231...	420.0	[0..1]	[244..1]
TRMD_MANSM - tRNA (guanine-N(1)-)-methyltransferase OS=Mannheimia succiniciproducens (strain MBEL55E) GN=trmD PE=...	420.0	[0..1]	[241..1]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFDILTLFP AMFDGPLTES IIRRAVERGF VDISLHNIRD YATDRHRVVD DAPYGGGDGM  60
   61 VMKVEPLAAC IEAVKAERPA ARVILTTPRG RRFDHDAARE LAGYEELIIV CGRYEGIDER 120
  121 VRDLFVDDEF SIGDFVLTGG ELAAMVMIDA VIRFIPGVLG SPGSAEYDSF ADGLLEYPQY 180
  181 TRPVEFRGVQ VPGVLLSGNH AEISRWRRQK ALELTRRVRP DLLHKAELSS SDRDCLAMLE 240
  241 REGEP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	115.0
Match:	1uajA
Description:	tRNA(m1G37)-methyltransferase TrmD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.77771076540343	bayes_pls_golite062009
methyltransferase activity	4.0901595540349	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.01958090893547	bayes_pls_golite062009
tRNA methyltransferase activity	3.35439517507384	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	3.10060782124076	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.87460031907348	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.59156540645412	bayes_pls_golite062009
rRNA methyltransferase activity	1.86192852581774	bayes_pls_golite062009
transferase activity	1.84002196534744	bayes_pls_golite062009
catalytic activity	1.16774040077235	bayes_pls_golite062009
N-methyltransferase activity	0.0655574594365502	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: