YRC Public Data Repository - Protein Structure Prediction

Protein:	LOLB_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	210 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LOLB_COXBU.

Description	E-value	Query Range	Subject Range
gi\|227836573, gi... - gi\|227886369\|ref\|ZP_04004174.1\| outer membrane lipoprotein LolB [Escherichia coli 83972], gi\|2278365... gi\|26247532, gi\|... - gi\|26247532\|ref\|NP_753572.1\| outer membrane lipoprotein LolB [Escherichia coli CFT073], gi\|26107933\|...	242.0	[0..15]	[209..29]
gi\|75255055 - gi\|75255055\|ref\|ZP_00726960.1\| COG3017: Outer membrane lipoprotein involved in outer membrane biogen...	242.0	[0..15]	[209..24]
gi\|115512551, gi... - gi\|117623427\|ref\|YP_852340.1\| outer membrane lipoprotein LolB [Escherichia coli APEC O1], gi\|1155125... gi\|91210430, gi\|... - gi\|91210430\|ref\|YP_540416.1\| outer membrane lipoprotein LolB [Escherichia coli UTI89], gi\|91072004\|g... gi\|226899929, gi... - gi\|237705172\|ref\|ZP_04535653.1\| outer membrane lipoprotein LolB [Escherichia sp. 3_2_53FAA], gi\|2268...	241.0	[0..15]	[209..29]
LOLB_PSEPK - Outer-membrane lipoprotein LolB OS=Pseudomonas putida (strain KT2440) GN=lolB PE=3 SV=1	240.0	[0..12]	[210..1]
LOLB_PSEP1 - Outer-membrane lipoprotein LolB OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=lolB PE=3 SV=1 tr\|E4RHR1\|E4RHR1... - Outer-membrane lipoprotein LolB OS=Pseudomonas putida (strain BIRD-1) GN=lolB PE=3 SV=1 tr\|I7C4X6\|I7C4X6... - Outer-membrane lipoprotein LolB OS=Pseudomonas putida (strain DOT-T1E) GN=lolB PE=3 SV=1	239.0	[0..12]	[210..1]
LOLB_PSEU2 - Outer-membrane lipoprotein LolB OS=Pseudomonas syringae pv. syringae (strain B728a) GN=lolB PE=3 SV=...	239.0	[0..12]	[210..1]
gi\|208732396, gi... - gi\|208815748\|ref\|ZP_03256927.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC404... LOLB_ECO5E - Outer-membrane lipoprotein LolB OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=lolB PE=3 SV=1 LOLB_ECOSE - Outer-membrane lipoprotein LolB OS=Escherichia coli (strain SE11) GN=lolB PE=3 SV=1 gi\|217318405, gi... - gi\|217327978\|ref\|ZP_03444060.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. TW145... LOLB_ECO8A - Outer-membrane lipoprotein LolB OS=Escherichia coli O8 (strain IAI1) GN=lolB PE=3 SV=1 LOLB_ECO57 - Outer-membrane lipoprotein LolB OS=Escherichia coli O157:H7 GN=lolB PE=3 SV=1 LOLB_ECO55 - Outer-membrane lipoprotein LolB OS=Escherichia coli (strain 55989 / EAEC) GN=lolB PE=3 SV=1 LOLB_ECOLU - Outer-membrane lipoprotein LolB OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=lolB PE=3... LOLB_ECOLI - Outer-membrane lipoprotein lolB precursor - Escherichia coli gi\|188015065, gi... - gi\|188015065\|gb\|EDU53187.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC4113], ... gi\|168771098, gi... - gi\|189360072\|gb\|EDU78491.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC4486], ... gi\|168776898, gi... - gi\|187767803\|gb\|EDU31647.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC4196], ... gi\|168782565, gi... - gi\|188999980\|gb\|EDU68966.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC4076], ... gi\|168787713, gi... - gi\|189372540\|gb\|EDU90956.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC869], g... gi\|24051513, gi\|... - gi\|24112608\|ref\|NP_707118.1\| outer membrane lipoprotein LolB [Shigella flexneri 2a str. 301], gi\|240... LOLB_ECODH - Outer-membrane lipoprotein LolB OS=Escherichia coli (strain K12 / DH10B) GN=lolB PE=3 SV=1 gi\|30040981, gi\|... - gi\|30062733\|ref\|NP_836904.1\| outer membrane lipoprotein LolB [Shigella flexneri 2a str. 2457T], gi\|3... gi\|195939097 - gi\|195939097\|ref\|ZP_03084479.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC402... EG11293 - lipoprotein localization factor / OM lipoprotein required for localization of lipoproteins; essentia... gi\|208728444, gi... - gi\|208808643\|ref\|ZP_03250980.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC420... gi\|194425836, gi... - gi\|75212647\|ref\|ZP_00712645.1\| COG3017: Outer membrane lipoprotein involved in outer membrane biogen... gi\|188494781, gi... - gi\|75511755\|ref\|ZP_00734384.1\| COG3017: Outer membrane lipoprotein involved in outer membrane biogen... LOLB_SHIBS - Outer-membrane lipoprotein LolB OS=Shigella boydii serotype 4 (strain Sb227) GN=lolB PE=3 SV=1 LOLB_SHIFL - Outer-membrane lipoprotein LolB OS=Shigella flexneri GN=lolB PE=3 SV=1 gi\|254792679, gi... - gi\|254792679\|ref\|YP_003077516.1\| chaperone for lipoproteins [Escherichia coli O157:H7 str. TW14359],... gi\|254161291, gi... - gi\|254161291\|ref\|YP_003044399.1\| outer membrane lipoprotein LolB precursor [Escherichia coli B str. ... gi\|254288099, gi... - gi\|254288099\|ref\|YP_003053847.1\| outer membrane lipoprotein LolB precursor [Escherichia coli BL21(DE... gi\|251784715, gi... - gi\|251784715\|ref\|YP_002999019.1\| hypothetical protein B21_01194 [Escherichia coli BL21], gi\|24237698... gi\|194437033, gi... - gi\|83587353\|ref\|ZP_00925981.1\| COG3017: Outer membrane lipoprotein involved in outer membrane biogen... LOLB_ECOBW - Outer-membrane lipoprotein LolB OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=lolB PE=3 SV=1 LOLB_ECO24 - Outer-membrane lipoprotein LolB OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=lolB PE=3 SV... gi\|124528408, gi... - gi\|124528408\|ref\|ZP_01699718.1\| outer membrane lipoprotein LolB [Escherichia coli B], gi\|124500640\|g... LOLB_ECOHS - Outer-membrane lipoprotein LolB OS=Escherichia coli O9:H4 (strain HS) GN=lolB PE=3 SV=1 gi\|1651599, gi\|8... - gi\|89108054\|ref\|AP_001834.1\| chaperone for lipoproteins [Escherichia coli str. K-12 substr. W3110], ... gi\|15830968, gi\|... - gi\|15830968\|ref\|NP_309741.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. Sakai], ... LOLB_SHIF8 - Outer-membrane lipoprotein LolB OS=Shigella flexneri serotype 5b (strain 8401) GN=lolB PE=3 SV=1 LOLB_ECOLC - Outer-membrane lipoprotein LolB OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=lolB P... EG11293 - lipoprotein localization factor / OM lipoprotein required for localization of lipoproteins; essentia... gi\|15801438, gi\|... - gi\|15801438\|ref\|NP_287455.1\| outer membrane lipoprotein LolB [Escherichia coli O157:H7 EDL933], gi\|1...	239.0	[0..15]	[209..7]
LOLB_SHIDS - Outer-membrane lipoprotein LolB OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=lolB PE=3 SV=1	239.0	[0..15]	[209..7]
LOLB_SALTI - Outer-membrane lipoprotein lolB OS=Salmonella typhi GN=lolB PE=3 SV=1 gi\|213426493 - gi\|213426493\|ref\|ZP_03359243.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica... gi\|213583755 - gi\|213583755\|ref\|ZP_03365581.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica... gi\|213609488 - gi\|213609488\|ref\|ZP_03369314.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica... gi\|214000991 - gi\|214000991\|ref\|ZP_03411726.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica... gi\|29137197, gi\|... - gi\|29141570\|ref\|NP_804912.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica se... gi\|16760671 - gi\|16760671\|ref\|NP_456288.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica se... gi\|213029196 - gi\|213029196\|ref\|ZP_03343643.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica... LOLB_SALTI - Outer-membrane lipoprotein LolB OS=Salmonella typhi GN=lolB PE=3 SV=1 gi\|213051788 - gi\|213051788\|ref\|ZP_03344666.1\| outer membrane lipoprotein LolB [Salmonella enterica subsp. enterica...	238.0	[0..15]	[209..7]
LOLB_PSEPF - Outer-membrane lipoprotein LolB OS=Pseudomonas fluorescens (strain Pf0-1) GN=lolB PE=3 SV=1	238.0	[0..12]	[210..1]

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Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLISNNEER SLRVRYCIAI ALSALLISGC TTLRLPNQST SVYHQQTWAQ RYYDLSRISQ  60
   61 WNIDGAFSIQ QPGKTIIAAY DWQQKGMNYR IRIHSSLDIY SVNISGRPGM VTLWRSPRQH 120
  121 YTASTPEQLM QQQLGWQLPL SNLYYWIRGI PAPGAYQADF DTYTHLIALQ QSGWHIRFSQ 180
  181 YTTVGSVDLP RTLQLSNGSL AVKIVVKHWQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.522879
Match:	1iwmA
Description:	Outer membrane lipoprotein receptor LolB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	2.94733677676109	bayes_pls_golite062009
protein transmembrane transporter activity	2.80163572604854	bayes_pls_golite062009
transporter activity	1.94557075462337	bayes_pls_golite062009
transmembrane transporter activity	1.8285077384404	bayes_pls_golite062009
substrate-specific transporter activity	1.57976971135135	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.4723961195197	bayes_pls_golite062009
protein binding	1.38954552030231	bayes_pls_golite062009
binding	1.0696248685847	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: