YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29654995, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	200 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29654995, gi|....

Description	E-value	Query Range	Subject Range
gi\|148510426, gi... - gi\|82737452\|ref\|ZP_00900301.1\| antioxidant, AhpC/Tsa family [Pseudomonas putida F1], gi\|82715427\|gb\|... gi\|26987820, gi\|... - gi\|26987820\|ref\|NP_743245.1\| anti-oxidant AhpCTSA family protein [Pseudomonas putida KT2440], gi\|249... tr\|I7B5X8\|I7B5X8... - Anti-oxidant AhpCTSA family protein OS=Pseudomonas putida (strain DOT-T1E) GN=tsaA PE=4 SV=1 tr\|E4R731\|E4R731... - Anti-oxidant AhpCTSA family protein OS=Pseudomonas putida (strain BIRD-1) GN=PPUBIRD1_1134 PE=4 SV=1	234.0	[0..1]	[200..1]
gi\|84319755, gi\|... - gi\|84319755\|ref\|ZP_00968145.1\| COG0450: Peroxiredoxin [Pseudomonas aeruginosa C3719], gi\|254236453\|r... gi\|194553174, gi... - gi\|84325803\|ref\|ZP_00973835.1\| COG0450: Peroxiredoxin [Pseudomonas aeruginosa 2192], gi\|254242189\|re... gi\|107103041 - gi\|107103041\|ref\|ZP_01366959.1\| hypothetical protein PaerPA_01004110 [Pseudomonas aeruginosa PACS2] gi\|9949678, gi\|1... - gi\|9949678\|gb\|AAG06917.1\|AE004773_6 probable peroxidase [Pseudomonas aeruginosa PAO1], gi\|15598725\|r... gi\|11351707 - pir\|\|G83204 probable peroxidase PA3529 [imported] - Pseudomonas aeruginosa (strain PAO1) gi\|115586749, gi... - gi\|46164288\|ref\|ZP_00205030.1\| COG0450: Peroxiredoxin [Pseudomonas aeruginosa UCBPP-PA14], gi\|116051... gi\|218770467, gi... - gi\|218890244\|ref\|YP_002439108.1\| putative peroxidase [Pseudomonas aeruginosa LESB58], gi\|218770467\|e... gi\|152986134, gi... - gi\|152986134\|ref\|YP_001347002.1\| putative peroxidase [Pseudomonas aeruginosa PA7], gi\|150961292\|gb\|A...	233.0	[0..1]	[200..1]
gi\|95109401 - gi\|95109401\|emb\|CAK14101.1\| putative peroxiredoxin (alkyl hydroperoxide reductase C) [Pseudomonas en... gi\|95109401, gi\|... - gi\|95109401\|emb\|CAK14101.1\| putative peroxiredoxin (alkyl hydroperoxide reductase C) [Pseudomonas en...	233.0	[0..1]	[200..1]
PRDX2_CRIGR - Peroxiredoxin-2 OS=Cricetulus griseus GN=PRDX2 PE=2 SV=3	233.0	[0..5]	[196..8]
gi\|62901916 - gi\|62901916\|gb\|AAY18909.1\| thioredoxin peroxidase 1-like [synthetic construct]	233.0	[0..3]	[196..30]
gi\|51980440 - gb\|AAH82149.1\| Unknown (protein for MGC:98395) [Xenopus laevis] PRDX2_MOUSE - Peroxiredoxin-2 OS=Mus musculus GN=Prdx2 PE=1 SV=3	232.0	[0..3]	[196..6]
gi\|60818622, gi\|... - gi\|61362999\|gb\|AAX42317.1\| peroxiredoxin 2 [synthetic construct], gi\|60818622\|gb\|AAX36471.1\| peroxir... PRDX2_MACFA - Peroxiredoxin-2 OS=Macaca fascicularis GN=PRDX2 PE=2 SV=3 gi\|114675617 - gi\|114675617\|ref\|XP_524127.2\| PREDICTED: peroxiredoxin 2 [Pan troglodytes] gi\|109123563, gi... - gi\|109123563\|ref\|XP_001109216.1\| PREDICTED: peroxiredoxin 2 isoform 5 [Macaca mulatta], gi\|109123561... PRDX2 - peroxiredoxin 2	232.0	[0..3]	[196..6]
gi\|89081026, gi\|... - gi\|89094680\|ref\|ZP_01167616.1\| antioxidant, AhpC/Tsa family protein [Oceanospirillum sp. MED92], gi\|...	232.0	[0..1]	[200..1]

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Predicted Domain #1

Region A:
Residues: [1-200]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVLVGREAP DFTVPAVLAN GDIVENFNLA EAIQNKYGLV FFYPLDFTFV CPSELIALDK  60
   61 AIADFQKRRV EVIGVSIDSQ FTHNAWRNTP VEKGGIGPVR YPLASDVTHS ICRSYGVEHV 120
  121 AGVALRGAFL IDKQGIVRSQ IVNDLPLGRS IPELLRLVDA LQFTEEHGEV CPANWKKGDP 180
  181 AMQASPDGVA KYLAENADNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.30103
Match:	1qmvA
Description:	Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alkyl hydroperoxide reductase activity	4.29610283853788	bayes_pls_golite062009
antioxidant activity	3.8464796631544	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
selenium binding	2.92496040718744	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
transcription regulator activity	2.30799114442278	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.23310780102446	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
transferase activity	1.26687471229876	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
protein binding	1.18479617596618	bayes_pls_golite062009
molecular transducer activity	1.11518182894524	bayes_pls_golite062009
signal transducer activity	1.11518182894524	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
peptide binding	0.374493676068876	bayes_pls_golite062009
	0.359224524631956	bayes_pls_golite062009
NADH dehydrogenase activity	0.23291471505999	bayes_pls_golite062009
copper ion binding	0.178842772364502	bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity	0.16328723676608	bayes_pls_golite062009
NADH dehydrogenase (quinone) activity	0.0434052164026002	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: