YRC Public Data Repository - Protein Structure Prediction

Protein:	KDSA_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	280 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KDSA_COXBU.

Description	E-value	Query Range	Subject Range
KDSA_METCA - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Methylococcus capsulatus GN=kdsA PE=3 SV=2 KDSA_METCA - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Methylococcus capsulatus (strain ATCC 33009 / NCIMB 111...	310.0	[0..5]	[275..13]
gi\|95112163 - gi\|95112163\|emb\|CAK16890.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Pseudomonas entomophila L48] KDSA_PSEE4 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Pseudomonas entomophila (strain L48) GN=kdsA PE=3 SV=1	309.0	[0..2]	[278..5]
KDSA_PELCD - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN...	309.0	[0..4]	[270..6]
KDSA1_PSEPK - 2-dehydro-3-deoxyphosphooctonate aldolase 1 OS=Pseudomonas putida (strain KT2440) GN=kdsA1 PE=3 SV=1 tr\|E4RFP8\|E4RFP8... - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Pseudomonas putida (strain BIRD-1) GN=kdsA_2 PE=3 SV=1 gi\|82715780, gi\|... - gi\|82737181\|ref\|ZP_00900033.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Pseudomonas putida F1], gi...	308.0	[0..2]	[278..5]
KDSA_HAHCH - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Hahella chejuensis (strain KCTC 2396) GN=kdsA PE=3 SV=1	308.0	[0..3]	[278..6]
gi\|11268172 - gi\|11268172\|pir\|\|D82700 2-dehydro-3-deoxyphosphooctonate aldolase XF1289 [imported] - Xylella fastid... gi\|9106278, gi\|1... - gi\|9106278\|gb\|AAF84098.1\|AE003962_8 2-dehydro-3-deoxyphosphooctonate aldolase [Xylella fastidiosa 9a...	307.0	[0..2]	[278..19]
gi\|28198452, gi\|... - ref\|NP_778766.1\| 2-dehydro-3-deoxyphosphooctonate aldolase [Xylella fastidiosa Temecula1], gi\|28056...	306.0	[0..2]	[278..12]
KDSA_HISS2 - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Histophilus somni (strain 2336) GN=kdsA PE=3 SV=1	305.0	[0..2]	[278..5]
KDSA_PSEPF - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Pseudomonas fluorescens (strain Pf0-1) GN=kdsA PE=3 SV=...	305.0	[0..2]	[278..5]
KDSA_LEGPL - 2-dehydro-3-deoxyphosphooctonate aldolase OS=Legionella pneumophila (strain Lens) GN=kdsA PE=3 SV=1	305.0	[0..3]	[271..1]

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Predicted Domain #1

Region A:
Residues: [1-280]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLMQIADFEI GLNNPLFLIA GPCVIESEAL VMDVAGELKS ITQQLDMPFI FKASFDKANR  60
   61 SSHLSYRGPG IEKGLTILEK VKKTLEVPII TDVHEDTPLQ EVAAVVDVLQ TPAFLCRQSN 120
  121 FIRSVAACGK PVNIKKGQFL APWEMKQVVA KAWATGNKKI MVCERGYSFG YNNLISDMRA 180
  181 LAILRETACP VIFDATHSVQ LPGGHGTNSG GQREFVPVLA RAATAAGIAG IFMETHPDPD 240
  241 RALSDGPNSW PLAKMQPLLE TLKELDKVVK NAGFLEQSSE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.522879
Match:	1o60A
Description:	Crystal structure of KDO-8-phosphate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-deoxy-8-phosphooctulonate synthase activity	4.43037733440316	bayes_pls_golite062009
3-deoxy-7-phosphoheptulonate synthase activity	2.72022882819661	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
fructose-bisphosphate aldolase activity	0.840107349031025	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.643395146148785	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.490222900376021	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
aldehyde-lyase activity	0.351872954170322	bayes_pls_golite062009
transaldolase activity	0.337067552042715	bayes_pls_golite062009
oxo-acid-lyase activity	0.0484922693826344	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: