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View Structure Prediction Details

Protein: TPIS_COXBU
Organism: Coxiella burnetii RSA 493
Length: 255 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPIS_COXBU.

Description E-value Query
Range
Subject
Range
gi|109505678 - gi|109505678|ref|XP_001064421.1| PREDICTED: similar to triosephosphate isomerase [Rattus norvegicus]
335.0 [0..2] [250..4]
gi|45825129 - gi|45825129|gb|AAS77472.1| AT02695p [Drosophila melanogaster]
335.0 [0..1] [250..102]
TPI1 - triosephosphate isomerase 1
TPIS_PANTR - Triosephosphate isomerase OS=Pan troglodytes GN=TPI1 PE=2 SV=2
gi|123993147, gi... - gi|124000137|gb|ABM87577.1| triosephosphate isomerase 1 [synthetic construct], gi|123993147|gb|ABM84...
334.0 [0..2] [250..4]
gi|223374 - gi|223374|prf||0801190A isomerase,triosephosphate
TPIS_RABIT - Triosephosphate isomerase OS=Oryctolagus cuniculus GN=TPI1 PE=1 SV=1
334.0 [0..2] [250..3]

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Predicted Domain #1
Region A:
Residues: [1-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRRPLVAGN WKMHGSRESV GQLLRALKHG CERLETAELA VFPPFVFLQQ CEEALMRTQI  60
   61 SWGAQDVSEF ERGAYTGEVS AAMLRDFHCR YVIVGHSERR QRHGETNEQV AAKVRAALRC 120
  121 GIRPIICVGE TEKQRNANQT LSVIKEQLAV VLQMNDNLAS LEGMVVAYEP IWAIGTGKNA 180
  181 TPSQAEEVHA ALRDQLHRQD ATLAESTRLL YGGSVKPDNA AALFEMPNID GALVGGASLE 240
  241 AEQFLKIGQQ CNQSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.69897
Match: 1wyiA
Description: human triosephosphate isomerase of new crystal form
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
triose-phosphate isomerase activity 5.94525596131351 bayes_pls_golite062009
intramolecular oxidoreductase activity 4.11751506069887 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses 3.62219160185043 bayes_pls_golite062009
isomerase activity 2.06271139232842 bayes_pls_golite062009
binding 1.80264931081179 bayes_pls_golite062009
catalytic activity 1.7524198174984 bayes_pls_golite062009
protein binding 0.33788557654084 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle