YRC Public Data Repository - Protein Structure Prediction

Protein:	RLME_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RLME_COXBU.

Description	E-value	Query Range	Subject Range
gi\|90580530, gi\|... - gi\|90580530\|ref\|ZP_01236335.1\| 23S rRNA methylase [Vibrio angustum S14], gi\|90438188\|gb\|EAS63374.1\| ... gi\|89072568, gi\|... - gi\|89072568\|ref\|ZP_01159140.1\| 23S rRNA methylase [Photobacterium sp. SKA34], gi\|89051672\|gb\|EAR5712...	190.0	[0..2]	[206..8]
RLME_COXBR - Ribosomal RNA large subunit methyltransferase E OS=Coxiella burnetii (strain RSA 331 / Henzerling II...	189.0	[0..1]	[212..1]
gi\|89080519, gi\|... - gi\|89095222\|ref\|ZP_01168145.1\| cell division protein FtsJ [Oceanospirillum sp. MED92], gi\|89080519\|g...	188.0	[0..3]	[207..6]
gi\|90326515, gi\|... - gi\|90412478\|ref\|ZP_01220481.1\| 23S rRNA methylase [Photobacterium profundum 3TCK], gi\|90326515\|gb\|EA...	187.0	[0..2]	[206..8]
gi\|254230590, gi... - gi\|75853710\|ref\|ZP_00761488.1\| COG0293: 23S rRNA methylase [Vibrio sp. Ex25], gi\|254230590\|ref\|ZP_04...	187.0	[0..2]	[207..8]
RLME_VIBPA - Ribosomal RNA large subunit methyltransferase E OS=Vibrio parahaemolyticus serotype O3:K6 (strain RI... RLME_VIBPA, RRMJ... - Ribosomal RNA large subunit methyltransferase J OS=Vibrio parahaemolyticus GN=rrmJ PE=3 SV=1, Riboso...	186.0	[0..2]	[207..8]
RLME_VIBF1 - Ribosomal RNA large subunit methyltransferase E OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=r...	186.0	[0..2]	[207..8]
RLME_RHILO - Ribosomal RNA large subunit methyltransferase E OS=Rhizobium loti (strain MAFF303099) GN=rlmE PE=3 S... RLME_RHILO, RRMJ... - Ribosomal RNA large subunit methyltransferase J OS=Rhizobium loti GN=rrmJ PE=3 SV=1, Ribosomal RNA l...	186.0	[0..3]	[208..29]
RLME_PHOPR - Ribosomal RNA large subunit methyltransferase E OS=Photobacterium profundum (strain SS9) GN=rlmE PE=... RRMJ_PHOPR, RLME... - Ribosomal RNA large subunit methyltransferase J OS=Photobacterium profundum GN=rrmJ PE=3 SV=1, Ribos...	186.0	[0..2]	[206..8]
RLME_SODGM - Ribosomal RNA large subunit methyltransferase E OS=Sodalis glossinidius (strain morsitans) GN=rlmE P...	186.0	[0..2]	[206..8]

Back

Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHSKRWLEE HEKDPYVKRA KKEGYPSRAA YKLLEIHQKY KLFKPSMNVI DLGAAPGGWS  60
   61 QVAKDLVGPK GVVIAIDLLP MQSMLDVIFI QGDFNEPEIF NQLEAIVAKK TLTGQVDLVI 120
  121 SDMAPNISGI KNVDQSRSLH LVELAWDCAQ KLLARGGTFL VKVFQGPGVD RFLINLRPYF 180
  181 NQVKFLKPSA SRSRSSEIYI LAGEFLGYNQ RV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.0
Match:	1eizA
Description:	RNA methyltransferase FtsJ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
N-methyltransferase activity	3.67177992319602	bayes_pls_golite062009
protein methyltransferase activity	3.5512266163483	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
histone methyltransferase activity	2.49492581548369	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	2.06652984530965	bayes_pls_golite062009
arginine N-methyltransferase activity	2.06652984530965	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
DNA-methyltransferase activity	1.63765148226572	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.63076727020333	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	1.26493190370687	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
tRNA methyltransferase activity	1.12859857407629	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.720411427168235	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.606920378432989	bayes_pls_golite062009
transcription regulator activity	0.316272167949639	bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity	0.299393192819978	bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity	0.299393192819978	bayes_pls_golite062009
DNA binding	0.26945982114479	bayes_pls_golite062009
O-methyltransferase activity	0.250946859465502	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	0.234572322347698	bayes_pls_golite062009
nucleic acid binding	0.0339414270453529	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: