YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29654078, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	192 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29654078, gi|....

Description	E-value	Query Range	Subject Range
gi\|75759648, gi\|... - gi\|75759648\|ref\|ZP_00739732.1\| HPR(SER) KINASE / PHOSPHATASE [Bacillus thuringiensis serovar israel...	258.0	[0..1]	[190..166]
gi\|47569263, gi\|... - gi\|47569263\|ref\|ZP_00239948.1\| Hpr(ser) kinase/phosphatase [Bacillus cereus G9241], gi\|47554034\|gb\|E...	258.0	[0..1]	[190..168]
HPRK_LACGA - HPr kinase/phosphorylase OS=Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1131 / NCIMB ... gi\|23003221 - gi\|23003221\|ref\|ZP_00046888.1\| COG1493: Serine kinase of the HPr protein, regulates carbohydrate met... gi\|226820650 - gi\|226820650\|ref\|ZP_03809769.1\| HPr kinase/phosphorylase [Lactobacillus gasseri MV-22] gi\|238854080, gi... - gi\|238854080\|ref\|ZP_04644430.1\| HPr(Ser) kinase/phosphatase [Lactobacillus gasseri 202-4], gi\|238833...	258.0	[0..1]	[192..126]
gi\|42740244, gi\|... - gi\|42784313\|ref\|NP_981560.1\| HPr kinase/phosphorylase [Bacillus cereus ATCC 10987], gi\|42740244\|gb\|A...	257.0	[0..1]	[190..166]
HPRK_LISMO - HPr kinase/phosphorylase OS=Listeria monocytogenes GN=hprK PE=3 SV=1 gi\|47015536, gi\|... - gi\|47096075\|ref\|ZP_00233676.1\| HPr(Ser) kinase/phosphatase [Listeria monocytogenes str. 1/2a F6854],... gi\|224503276 - gi\|224503276\|ref\|ZP_03671583.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL R2-561] gi\|47018857, gi\|... - gi\|47092769\|ref\|ZP_00230554.1\| HPr(Ser) kinase/phosphatase [Listeria monocytogenes str. 4b H7858], g... gi\|224499840 - gi\|224499840\|ref\|ZP_03668189.1\| HPr kinase/phosphorylase [Listeria monocytogenes Finland 1988] HPRK_LISMF - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=hprK PE=3 SV=1 HPRK_LISMO - HPr kinase/phosphorylase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=hpr... gi\|126942452, gi... - gi\|254900379\|ref\|ZP_05260303.1\| HPr kinase/phosphorylase [Listeria monocytogenes J0161], gi\|15318494... gi\|153197211, gi... - gi\|254831094\|ref\|ZP_05235749.1\| HPr kinase/phosphorylase [Listeria monocytogenes 10403S], gi\|1531972... gi\|254913382, gi... - gi\|254913382\|ref\|ZP_05263394.1\| HPr kinase/phosphorylase [Listeria monocytogenes J2818], gi\|15319214... gi\|153168591, gi... - gi\|254872173\|ref\|ZP_05244883.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL N1-017], gi\|153... gi\|153175735, gi... - gi\|254828058\|ref\|ZP_05232745.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL N3-165], gi\|153... gi\|254937763, gi... - gi\|254937763\|ref\|ZP_05269460.1\| HPr kinase/phosphorylase [Listeria monocytogenes F6900], gi\|15318057... HPRK_LISMH - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=hprK PE=3 SV=1 gi\|153204054, gi... - gi\|254932276\|ref\|ZP_05265635.1\| HPr kinase/phosphorylase [Listeria monocytogenes HPB2262], gi\|153204... HPRK_LISMC - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=hprK PE=3 SV=1 gi\|254853515 - gi\|254853515\|ref\|ZP_05242863.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL R2-503] gi\|254879191 - gi\|254879191\|ref\|ZP_05251901.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J2-071] gi\|254992085 - gi\|254992085\|ref\|ZP_05274275.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J2-064] gi\|255027005 - gi\|255027005\|ref\|ZP_05298991.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J2-003] HPRK_LISMC - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=hprK PE=3 SV=1 gi\|255521862 - gi\|255521862\|ref\|ZP_05389099.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J1-175]	257.0	[0..1]	[192..124]
HPRK_LACJO - HPr kinase/phosphorylase OS=Lactobacillus johnsonii GN=hprK PE=3 SV=1 HPRK_LACJO - HPr kinase/phosphorylase OS=Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533) GN=hprK PE...	256.0	[0..1]	[192..126]
HPRK_LISIN - HPr kinase/phosphorylase OS=Listeria innocua GN=hprK PE=3 SV=1 HPRK_LISIN - HPr kinase/phosphorylase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=hprK PE=3 SV=1	256.0	[0..1]	[192..124]
gi\|254997674 - gi\|254997674\|dbj\|BAH88275.1\| HPr(serine) kinase/phosphatase [Streptococcus mutans NN2025] HPRK_STRMU - HPr kinase/phosphorylase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) GN=hprK PE=... HPRK_STRMU - HPr kinase/phosphorylase OS=Streptococcus mutans GN=hprK PE=3 SV=1	256.0	[0..1]	[192..123]
gi\|228930162, gi... - gi\|228930162\|ref\|ZP_04093171.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar pondicherie... gi\|228917766, gi... - gi\|228917766\|ref\|ZP_04081306.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar pulsiensis ... gi\|228948879, gi... - gi\|228948879\|ref\|ZP_04111154.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar monterrey B... gi\|228936446, gi... - gi\|228936446\|ref\|ZP_04099244.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar andalousien... gi\|228596075, gi... - gi\|229187371\|ref\|ZP_04314514.1\| HPr kinase/phosphorylase [Bacillus cereus BGSC 6E1], gi\|228596075\|gb... gi\|228658762, gi... - gi\|229124667\|ref\|ZP_04253848.1\| HPr kinase/phosphorylase [Bacillus cereus 95/8201], gi\|228658762\|gb\|... gi\|65317134 - gi\|65317134\|ref\|ZP_00390093.1\| COG1493: Serine kinase of the HPr protein, regulates carbohydrate met...	255.0	[0..1]	[190..148]
gi\|227535584, gi... - gi\|227535584\|ref\|ZP_03965633.1\| HPr kinase [Lactobacillus paracasei subsp. paracasei ATCC 25302], gi... HPRK_LACCA - HPr kinase/phosphorylase OS=Lactobacillus casei GN=hprK PE=1 SV=1 HPRK_LACC3 - HPr kinase/phosphorylase OS=Lactobacillus casei (strain ATCC 334) GN=hprK PE=3 SV=1 gi\|224453415, gi... - gi\|239631201\|ref\|ZP_04674232.1\| HPr kinase/phosphorylase kinase/phosphorylase [Lactobacillus paracas... HPRK_LACCB - HPr kinase/phosphorylase OS=Lactobacillus casei (strain BL23) GN=hprK PE=3 SV=1 gi\|6688477 - gi\|6688477\|emb\|CAB65151.1\| HprK protein [Lactobacillus casei subsp. casei ATCC 393]	254.0	[0..1]	[191..125]

Back

Predicted Domain #1

Region A:
Residues: [1-192]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLHQSPGET PGPLKQTWHA NFLVIDKMGV LITGEANIGK SELSLALIDR GHQLVCDDVI  60
   61 DLKQENNQLI GSCPSVANGY ILITGIGIID VPKLFGLDAV VNQHEVHLSI SLVKPEKMPL 120
  121 LDDPLNPLYR TEIILGINVP KILFPIHPGR NLPLLIETLV RNHRLKMEGY DSSHHFHEHF 180
  181 RKARDNYDSK KN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.0
Match:	1jb1A
Description:	HPr kinase HprK C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.96595957357027	bayes_pls_golite062009
phosphoenolpyruvate carboxykinase activity	0.895807668315489	bayes_pls_golite062009
carbon-carbon lyase activity	0.626079896377643	bayes_pls_golite062009
lyase activity	0.600389586904626	bayes_pls_golite062009
carboxy-lyase activity	0.593189334075365	bayes_pls_golite062009
binding	0.456582751079595	bayes_pls_golite062009
phosphoenolpyruvate carboxykinase (ATP) activity	0.0272102212862302	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: