YRC Public Data Repository - Protein Structure Prediction

Protein:	UBIC_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	185 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBIC_COXBU.

Description	E-value	Query Range	Subject Range
gi\|165923906, gi... - gi\|165923906\|ref\|ZP_02219738.1\| putative chorismate--pyruvate lyase [Coxiella burnetii RSA 334], gi\|... gi\|212011820, gi... - gi\|212213410\|ref\|YP_002304346.1\| chorismate--pyruvate lyase [Coxiella burnetii CbuG_Q212], gi\|212011... gi\|154705740, gi... - gi\|94492523\|ref\|ZP_01299730.1\| hypothetical protein CburD_01000101 [Coxiella burnetii Dugway 7E9-12]... gi\|212013722, gi... - gi\|212219460\|ref\|YP_002306247.1\| chorismate--pyruvate lyase [Coxiella burnetii CbuK_Q154], gi\|212013... gi\|153209102, gi... - gi\|153209102\|ref\|ZP_01947245.1\| putative chorismate--pyruvate lyase [Coxiella burnetii 'MSU Goat Q17...	194.0	[0..1]	[185..1]
gi\|84355379 - gi\|84355379\|ref\|ZP_00980264.1\| COG3161: 4-hydroxybenzoate synthetase (chorismate lyase) [Burkholderi...	186.0	[0..4]	[185..11]
UBIC_BURCM - Probable chorismate pyruvate-lyase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=ubiC PE...	183.0	[0..4]	[185..11]
gi\|67155518, gi\|... - gi\|67155518\|ref\|ZP_00417146.1\| Chorismate lyase [Azotobacter vinelandii AvOP], ref\|ZP_00092215.1\| CO... gi\|67087319, gi\|... - gi\|67155518\|ref\|ZP_00417146.1\| Chorismate lyase [Azotobacter vinelandii AvOP], gi\|67087319\|gb\|EAM067...	183.0	[0..6]	[185..8]
UBIC_PSEAB - Probable chorismate pyruvate-lyase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=ubiC PE=3 SV=1	183.0	[0..1]	[184..1]
UBIC_BURCA - Probable chorismate pyruvate-lyase OS=Burkholderia cenocepacia (strain AU 1054) GN=ubiC PE=3 SV=1 UBIC_BURCH - Probable chorismate pyruvate-lyase OS=Burkholderia cenocepacia (strain HI2424) GN=ubiC PE=3 SV=1	181.0	[0..4]	[185..7]
UBIC2_PSEPF - Probable chorismate pyruvate-lyase 2 OS=Pseudomonas fluorescens (strain Pf0-1) GN=ubiC2 PE=3 SV=1	181.0	[0..7]	[185..9]
UBIC_PSEU2 - Probable chorismate pyruvate-lyase OS=Pseudomonas syringae pv. syringae (strain B728a) GN=ubiC PE=3 ...	181.0	[0..6]	[181..12]
gi\|124894387, gi... - gi\|84362464\|ref\|ZP_00987085.1\| COG3161: 4-hydroxybenzoate synthetase (chorismate lyase) [Burkholderi...	181.0	[0..12]	[185..12]
gi\|134139689, gi... - gi\|67545042\|ref\|ZP_00422967.1\| Chorismate lyase [Burkholderia vietnamiensis G4], gi\|67533797\|gb\|EAM3...	179.0	[0..12]	[185..12]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKQLFWAPQ NEIPSTLWTA NERSWLTHPG SLTQRLRKTT DGQIQHHLLR EVFDAPVDEE  60
   61 TQLLGISQPE LALIREIEWR YFESLWVAGR VVIPKKTLER EGSPLNHIGE RSLGDILFAN 120
  121 AKFTRGDLEF RQITADHPYY FYVKEIANGS CIWARRSLFY FERDPLLVSE IFSPALFLES 180
  181 SVSND

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.0
Match:	1g1bA
Description:	Chorismate lyase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
chorismate lyase activity	2.05519151646174	bayes_pls_golite062009
transcription regulator activity	1.57377397378644	bayes_pls_golite062009
transcription factor activity	0.69320946586875	bayes_pls_golite062009
nucleic acid binding	0.57419587564833	bayes_pls_golite062009
DNA binding	0.56992408578543	bayes_pls_golite062009
catalytic activity	0.43947186099223	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: