YRC Public Data Repository - Protein Structure Prediction

Protein:	APT_ENTFA
Organism:	Enterococcus faecalis V583
Length:	170 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APT_ENTFA.

Description	E-value	Query Range	Subject Range
APT_CARHZ - Adenine phosphoribosyltransferase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 60...	170.0	[0..1]	[170..1]
APT1_WHEAT - Adenine phosphoribosyltransferase 1 OS=Triticum aestivum GN=APT1 PE=2 SV=1	167.0	[0..3]	[169..10]
APT3_ARATH - Adenine phosphoribosyltransferase 3 OS=Arabidopsis thaliana GN=APT3 PE=1 SV=1	166.0	[0..3]	[170..15]
gi\|222523585, gi... - gi\|222523585\|ref\|YP_002568055.1\| adenine phosphoribosyltransferase [Chloroflexus sp. Y-400-fl], gi\|2... APT_CHLAA - Adenine phosphoribosyltransferase OS=Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl...	166.0	[0..2]	[170..5]
gi\|15157388, gi\|... - gi\|15889512\|ref\|NP_355193.1\| adenine phosphoribosyltransferase [Agrobacterium tumefaciens str. C58],... gi\|25286869 - gi\|25286869\|pir\|\|A97628 adenine phosphoribosyltransferase (AF109172) [imported] - Agrobacterium tume...	166.0	[0..2]	[170..25]
gi\|9711921 - gi\|9711921\|dbj\|BAB08003.1\| Adenine phosphoribosyltransferase [Hordeum vulgare subsp. vulgare]	166.0	[0..3]	[169..10]
APT_CLOP1 - Adenine phosphoribosyltransferase OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290... APT_CLOPS - Adenine phosphoribosyltransferase OS=Clostridium perfringens (strain SM101 / Type A) GN=apt PE=3 SV=... APT_CLOPE - Adenine phosphoribosyltransferase OS=Clostridium perfringens GN=apt PE=3 SV=1 gi\|169298314, gi... - gi\|169343754\|ref\|ZP_02864753.1\| adenine phosphoribosyltransferase [Clostridium perfringens C str. JG... gi\|170714343, gi... - gi\|170714343\|gb\|EDT26525.1\| adenine phosphoribosyltransferase [Clostridium perfringens CPE str. F496... gi\|170713170, gi... - gi\|170713170\|gb\|EDT25352.1\| adenine phosphoribosyltransferase [Clostridium perfringens B str. ATCC 3... gi\|168204878, gi... - gi\|170663704\|gb\|EDT16387.1\| adenine phosphoribosyltransferase [Clostridium perfringens E str. JGS198... APT_CLOPE - Adenine phosphoribosyltransferase OS=Clostridium perfringens (strain 13 / Type A) GN=apt PE=3 SV=1 gi\|182624396, gi... - gi\|182624396\|ref\|ZP_02952180.1\| adenine phosphoribosyltransferase [Clostridium perfringens D str. JG...	166.0	[0..1]	[170..1]
APT_DESHD - Adenine phosphoribosyltransferase OS=Desulfitobacterium hafniense (strain DCB-2 / DSM 10664) GN=apt ...	165.0	[0..1]	[170..1]
APT_GEOKA - Adenine phosphoribosyltransferase OS=Geobacillus kaustophilus (strain HTA426) GN=apt PE=3 SV=1 APT_GEOKA - Adenine phosphoribosyltransferase OS=Geobacillus kaustophilus GN=apt PE=3 SV=1	165.0	[0..1]	[170..1]

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Predicted Domain #1

Region A:
Residues: [1-170]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLRDYIASI PDYPEKGIVF RDISPLMANG DAYREATKQI VDYAKEKRID MVVGPEARGF  60
   61 IVGCPVAYEL GVGFAPVRKK GKLPRETIEV TYDLEYGSDT LTLHKDAITP GQRVLICDDL 120
  121 LATGGTIKAT IELVEQLGGI VVGCAFLIEL MDLHGRDKID GYDIVTLMEY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.154902
Match:	1oreA
Description:	Human Adenine Phosphoribosyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	4.07252508868782	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	3.97944228585882	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	3.89356447922614	bayes_pls_golite062009
transferase activity	3.88709784255536	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.6596316647688	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.45489477082258	bayes_pls_golite062009
purine binding	1.3774977535406	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
transcription regulator activity	1.09798789282825	bayes_pls_golite062009
nucleic acid binding	1.07284130528063	bayes_pls_golite062009
DNA binding	0.854593555814443	bayes_pls_golite062009
adenine binding	0.817887117933035	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.691442295634288	bayes_pls_golite062009
transcription factor activity	0.339219342075596	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: