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View Structure Prediction Details

Protein: HGNC:9393|MIM:17...
Organism: SPECIES UNKNOWN
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HGNC:9393|MIM:17....

Description E-value Query
Range
Subject
Range
gi|54303904 - gi|54303904|gb|AAV33302.1| aging-associated gene 6 protein [Homo sapiens]
607.0 [0..1] [672..1]
gi|60826237 - gi|60826237|gb|AAX36750.1| protein kinase C alpha [synthetic construct]
606.0 [0..1] [672..1]
KPCA_RAT - Protein kinase C alpha type OS=Rattus norvegicus GN=Prkca PE=1 SV=3
gi|56914 - gi|56914|emb|CAA30266.1| unnamed protein product [Rattus rattus]
603.0 [0..1] [672..1]
gi|66717, gi|499... - gi|74151073|dbj|BAE27664.1| unnamed protein product [Mus musculus], gi|66792589|gb|AAH96493.1| Prkca...
gi|117616652 - gi|117616652|gb|ABK42344.1| protein kinase C alpha [synthetic construct]
602.0 [0..1] [672..1]
KPCA_BOVIN - Protein kinase C alpha type OS=Bos taurus GN=PRKCA PE=1 SV=3
601.0 [0..1] [672..1]
KPCA_RABIT - Protein kinase C alpha type OS=Oryctolagus cuniculus GN=PRKCA PE=2 SV=3
600.0 [0..1] [672..1]
gi|60098665, gi|... - gi|61098322|ref|NP_001012822.1| protein kinase C, alpha [Gallus gallus], gi|60098665|emb|CAH65163.1|...
595.0 [0..1] [671..1]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVFPGNDS TASQDVANRF ARKGALRQKN VHEVKDHKFI ARFFKQPTFC SHCTDFIWGF  60
   61 GKQGFQCQVC CFVVHKRCHE FVTFSCP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.69897
Match: 1tbnA
Description: NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [88-186]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GADKGPDTDD PRSKHKFKIH TYGSPTFCDH CGSLLYGLIH QGMKCDTCDM NVHKQCVINV  60
   61 PSLCGMDHTE KRGRIYLKAE VADEKLHVTV RDAKNLIPM

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.5
Match: 1tbnA
Description: NMR STRUCTURE OF A PROTEIN KINASE C-G PHORBOL-BINDING DOMAIN, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [187-232]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPNGLSDPYV KLKLIPDPKN ESKQKTKTIR STLNPQWNES FTFKLK

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 6.0
Match: PF00168.21
Description: No description for PF00168.21 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [233-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSDKDRRLSV EIWDWDRTTR NDFMGSLSFG VSELMKMPAS GWYKLLNQEE GEYYNVPIPE  60
   61 GDEEGNMELR QKFEKAKLGP AGNKVISPSE DRKQPSNNLD RVKLTDFNFL MVLGKGSFGK 120
  121 VMLADRKGTE ELYAIKILKK DVVIQDDDVE CTMVEKRVLA LLDKPPFLTQ LHSCFQTVDR 180
  181 LYFVMEYVNG GDLMYHIQQV GKFKEPQAVF YAAEISIGLF FLHKRGIIYR DLKLDNVMLD 240
  241 SEGHIKIADF GMCKEHMMDG VTTRTFCGTP DYIAPEIIAY QPYGKSVDWW AYGVLLYEML 300
  301 AGQPPFDGED EDELFQSIME HNVSYPKSLS KEAVSICKGL MTKHPAKRLG CGPEGERDVR 360
  361 EHAFFRRIDW EKLENRE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.0
Match: 1k9aA
Description: Carboxyl-terminal src kinase (csk)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [610-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQPPFKPKVC GKGAENFDKF FTRGQPVLTP PDQLVIANID QSDFEGFSYV NPQFVHPILQ  60
   61 SAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.045757
Match: 2i0eA
Description: No description for 2i0eA was found.

YRC Informatics Platform - Version 3.0
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