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View Structure Prediction Details

Protein: HGNC:13414|Ensem...
Organism: SPECIES UNKNOWN
Length: 142 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HGNC:13414|Ensem....

Description E-value Query
Range
Subject
Range
gi|76676926 - gi|76676926|ref|XP_582666.2| PREDICTED: similar to Group IIE secretory phospholipase A2 precursor (P...
1.0E-47 [11..142] [304..435]
PA2A8_DABPA - Acidic phospholipase A2 VP8 OS=Daboia palaestinae PE=3 SV=1
PA28_VIPPA - Phospholipase A2 homolog VP8 OS=Vipera palaestinae PE=3 SV=1
3.0E-45 [6..142] [3..137]
gi|50874500 - gi|50874500|emb|CAE47239.1| ammodytin I2(C) variant [Vipera ammodytes meridionalis]
3.0E-45 [6..142] [3..137]
PA2BB_GLOHA - Basic phospholipase A2 B OS=Gloydius halys PE=1 SV=2
6.0E-45 [7..142] [4..138]
gi|50874508 - gi|50874508|emb|CAE47243.1| ammodytin I2(C) variant [Vipera ammodytes montandoni]
8.0E-45 [6..142] [3..137]
gi|45934756, gi|... - gi|45934756|gb|AAS79430.1| phospholipase A2 [Sistrurus catenatus tergeminus], gi|166012678|gb|ABY779...
9.0E-45 [7..142] [4..138]
gi|50874484, gi|... - gi|50874488|emb|CAE47233.1| ammodytin I2(A') isoform [Vipera ammodytes ammodytes], gi|50874484|emb|C...
9.0E-45 [6..142] [3..137]
PA2B2_BOTJR - Basic phospholipase A2 bothropstoxin-2 OS=Bothrops jararacussu PE=1 SV=1
1.0E-44 [7..142] [4..138]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSPHVLVFL CLLVALVTGN LVQFGVMIEK MTGKSALQYN DYGCYCGIGG SHWPVDQTDW  60
   61 CCHAHDCCYG RLEKLGCEPK LEKYLFSVSE RGIFCAGRTT CQRLTCECDK RAALCFRRNL 120
  121 GTYNRKYAHY PNKLCTGPTP PC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 1b4wA
Description: Snake phospholipase A2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipase A2 activity 5.6430968678228 bayes_pls_golite062009
phospholipase activity 5.38445724291842 bayes_pls_golite062009
calcium-dependent phospholipase A2 activity 4.05813159633475 bayes_pls_golite062009
lipase activity 3.51338748073942 bayes_pls_golite062009
cell surface binding 3.03976629465117 bayes_pls_golite062009
carboxylesterase activity 2.68079964970429 bayes_pls_golite062009
receptor binding 2.23831898285432 bayes_pls_golite062009
binding 1.6033670102211 bayes_pls_golite062009
protein binding 1.47445022237761 bayes_pls_golite062009
hydrolase activity 1.32355620269997 bayes_pls_golite062009
catalytic activity 0.975181414554529 bayes_pls_golite062009
glycosaminoglycan binding 0.453108206649759 bayes_pls_golite062009
heparin binding 0.43572775235244 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.374809125250581 bayes_pls_golite062009

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