YRC Public Data Repository - Protein Structure Prediction

Protein:	HGNC:2847\|MIM:60...
Organism:	SPECIES UNKNOWN
Length:	773 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HGNC:2847|MIM:60....

Description	E-value	Query Range	Subject Range
gi\|117646832 - gi\|117646832\|emb\|CAL37531.1\| hypothetical protein [synthetic construct] DGCR8_MOUSE - Microprocessor complex subunit DGCR8 OS=Mus musculus GN=Dgcr8 PE=1 SV=2	0.0	[1..773]	[1..773]
gi\|114685157 - gi\|114685157\|ref\|XP_001167234.1\| PREDICTED: DiGeorge syndrome critical region gene 8 isoform 2 [Pan ...	0.0	[1..773]	[1..783]
gi\|109493564, gi... - gi\|157786750\|ref\|NP_001099335.1\| DiGeorge syndrome critical region gene 8 [Rattus norvegicus], gi\|14...	0.0	[1..773]	[1..773]
gi\|73995913 - gi\|73995913\|ref\|XP_543542.2\| PREDICTED: similar to DiGeorge syndrome critical region gene 8 [Canis f...	0.0	[20..708]	[1..689]
gi\|76672808 - gi\|76672808\|ref\|XP_881196.1\| PREDICTED: similar to DGCR8 protein (DiGeorge syndrome critical region ...	0.0	[1..773]	[1..763]
gi\|50756249 - gi\|50756249\|ref\|XP_415079.1\| PREDICTED: similar to DiGeorge syndrome critical region gene 8 [Gallus ...	0.0	[1..773]	[1..775]

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Predicted Domain #1

Region A:
Residues: [1-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METDESPSPL PCGPAGEAVM ESRARPFQAL PREQSPPPPL QTSSGAEVMD VGSGGDGQSE  60
   61 LPAEDPFNFY GASLLSKGSF SKGRLLIDPN CSGHSPRTAR HAPAVRKFSP DLKLLKDVKI 120
  121 SVSFTESCRS KDRKVLYTGA ERDVRAECGL LLSPVSGDVH ACPFGGSVGD GVGIGGESAD 180
  181 KKDEENELDQ EKRVEYAVLD ELEDFTDNLE LDEEGAGGFT AKAIVQRDRV DEEALNF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [238-346]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYEDDFDNDV DALLEEGLCA PKKRRTEEKY GGDSDHPSDG ETSVQPMMTK IKTVLKSRGR  60
   61 PPTEPLPDGW IMTFHNSGVP VYLHRESRVV TWSRPYFLGT GSIRKHDPP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [347-435]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSSIPCLHYK KMKDNEEREQ SSDLTPSGDV SPVKPLSRSA ELEFPLDEPD SMGADPGPPD  60
   61 EKDPLGAEAA PGALGQVKAK VEVCKDESV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [436-773]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLEEFRSYLE KRFDFEQVTV KKFRTWAERR QFNREMKRKQ AESERPILPA NQKLITLSVQ  60
   61 DAPTKKEFVI NPNGKSEVCI LHEYMQRVLK VRPVYNFFEC ENPSEPFGAS VTIDGVTYGS 120
  121 GTASSKKLAK NKAARATLEI LIPDFVKQTS EEKPKDSEEL EYFNHISIED SRVYELTSKA 180
  181 GLLSPYQILH ECLKRNHGMG DTSIKFEVVP GKNQKSEYVM ACGKHTVRGW CKNKRVGKQL 240
  241 ASQKILQLLH PHVKNWGSLL RMYGRESSKM VKQETSDKSV IELQQYAKKN KPNLHILSKL 300
  301 QEEMKRLAEE REETRKKPKM SIVASAQPGG EPLCTVDV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.154902
Match:	2yt4A
Description:	No description for 2yt4A was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits