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View Structure Prediction Details

Protein: HGNC:2847|MIM:60...
Organism: SPECIES UNKNOWN
Length: 773 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HGNC:2847|MIM:60....

Description E-value Query
Range
Subject
Range
gi|117646832 - gi|117646832|emb|CAL37531.1| hypothetical protein [synthetic construct]
DGCR8_MOUSE - Microprocessor complex subunit DGCR8 OS=Mus musculus GN=Dgcr8 PE=1 SV=2
0.0 [1..773] [1..773]
gi|114685157 - gi|114685157|ref|XP_001167234.1| PREDICTED: DiGeorge syndrome critical region gene 8 isoform 2 [Pan ...
0.0 [1..773] [1..783]
gi|109493564, gi... - gi|157786750|ref|NP_001099335.1| DiGeorge syndrome critical region gene 8 [Rattus norvegicus], gi|14...
0.0 [1..773] [1..773]
gi|73995913 - gi|73995913|ref|XP_543542.2| PREDICTED: similar to DiGeorge syndrome critical region gene 8 [Canis f...
0.0 [20..708] [1..689]
gi|76672808 - gi|76672808|ref|XP_881196.1| PREDICTED: similar to DGCR8 protein (DiGeorge syndrome critical region ...
0.0 [1..773] [1..763]
gi|50756249 - gi|50756249|ref|XP_415079.1| PREDICTED: similar to DiGeorge syndrome critical region gene 8 [Gallus ...
0.0 [1..773] [1..775]

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Predicted Domain #1
Region A:
Residues: [1-237]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METDESPSPL PCGPAGEAVM ESRARPFQAL PREQSPPPPL QTSSGAEVMD VGSGGDGQSE  60
   61 LPAEDPFNFY GASLLSKGSF SKGRLLIDPN CSGHSPRTAR HAPAVRKFSP DLKLLKDVKI 120
  121 SVSFTESCRS KDRKVLYTGA ERDVRAECGL LLSPVSGDVH ACPFGGSVGD GVGIGGESAD 180
  181 KKDEENELDQ EKRVEYAVLD ELEDFTDNLE LDEEGAGGFT AKAIVQRDRV DEEALNF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [238-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYEDDFDNDV DALLEEGLCA PKKRRTEEKY GGDSDHPSDG ETSVQPMMTK IKTVLKSRGR  60
   61 PPTEPLPDGW IMTFHNSGVP VYLHRESRVV TWSRPYFLGT GSIRKHDPP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.327 0.200 double-stranded RNA binding a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.281 0.063 double-stranded RNA binding d.32.1 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase
View Download 0.356 0.044 double-stranded RNA binding c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.345 0.030 double-stranded RNA binding d.129.1 TATA-box binding protein-like
View Download 0.367 0.009 double-stranded RNA binding a.24.17 Group V grass pollen allergen

Predicted Domain #3
Region A:
Residues: [347-435]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSSIPCLHYK KMKDNEEREQ SSDLTPSGDV SPVKPLSRSA ELEFPLDEPD SMGADPGPPD  60
   61 EKDPLGAEAA PGALGQVKAK VEVCKDESV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.393 0.047 double-stranded RNA binding a.4.12 TrpR-like
View Download 0.263 0.023 double-stranded RNA binding a.60.9 lambda integrase-like, N-terminal domain
View Download 0.316 0.019 double-stranded RNA binding a.118.14 FliG

Predicted Domain #4
Region A:
Residues: [436-773]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLEEFRSYLE KRFDFEQVTV KKFRTWAERR QFNREMKRKQ AESERPILPA NQKLITLSVQ  60
   61 DAPTKKEFVI NPNGKSEVCI LHEYMQRVLK VRPVYNFFEC ENPSEPFGAS VTIDGVTYGS 120
  121 GTASSKKLAK NKAARATLEI LIPDFVKQTS EEKPKDSEEL EYFNHISIED SRVYELTSKA 180
  181 GLLSPYQILH ECLKRNHGMG DTSIKFEVVP GKNQKSEYVM ACGKHTVRGW CKNKRVGKQL 240
  241 ASQKILQLLH PHVKNWGSLL RMYGRESSKM VKQETSDKSV IELQQYAKKN KPNLHILSKL 300
  301 QEEMKRLAEE REETRKKPKM SIVASAQPGG EPLCTVDV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.154902
Match: 2yt4A
Description: No description for 2yt4A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle